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This case is unique as the patient was in circulatory shock with MODS from rhabdomyolysis on arrival and had not suffered a cardiac arrest. We believe this to be the first reported case of full recovery from such an extreme metabolic disturbance in this context, and discuss the relevance of profound acidosis to early clinical decision-making.<\/jats:p>","DOI":"10.1177\/1751143719870102","type":"journal-article","created":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T07:46:02Z","timestamp":1567669562000},"page":"78-82","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Recovery from profound acidosis (pH 6.685) in multi-organ dysfunction syndrome"],"prefix":"10.1177","volume":"22","author":[{"given":"Eryl A","family":"Davies","sequence":"first","affiliation":[{"name":"Critical Care Unit, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Saleh","sequence":"additional","affiliation":[{"name":"Critical Care Unit, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Bannard-Smith","sequence":"additional","affiliation":[{"name":"Critical Care Unit, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,9,5]]},"reference":[{"key":"bibr1-1751143719870102","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511641947.021"},{"key":"bibr2-1751143719870102","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1972.32.1.59"},{"key":"bibr3-1751143719870102","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199708000-00035"},{"key":"bibr4-1751143719870102","volume-title":"ABL800 FLEX Reference manual","author":"Radiometer Medical ApS","year":"2008"},{"key":"bibr5-1751143719870102","volume-title":"Clinical and biochemical aspects of lactic acidosis","author":"Cohen RD","year":"1976"},{"key":"bibr6-1751143719870102","unstructured":"Higgins C. Temperature correction of blood gas and pH measurement \u2013 an unresolved controversy, https:\/\/acutecaretesting.org\/en\/articles\/temperature-correction-of-blood-gas-and-ph-measurement-an-unresolved-controversy (2016, accessed 10 March 2018)."},{"key":"bibr7-1751143719870102","doi-asserted-by":"publisher","DOI":"10.1136\/emj.19.2.169"},{"key":"bibr8-1751143719870102","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199302183280717"},{"key":"bibr9-1751143719870102","doi-asserted-by":"crossref","unstructured":"Mitchell CD, Isaacs D, and Larcher VF. Complete recovery after profound acidosis (pH 6.48).\n                      Arch Dis Child\n                      1984; 59: 908\u2013909.","DOI":"10.1136\/adc.59.9.908-b"},{"key":"bibr10-1751143719870102","doi-asserted-by":"crossref","unstructured":"Khan MI, Miller MT, and Bartlett M. 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