{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:41:26Z","timestamp":1777729286997,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2021,3,15]],"date-time":"2021-03-15T00:00:00Z","timestamp":1615766400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Intensive Care Society"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Whilst the management of Coronavirus disease-2019 (COVID-19) has evolved in response to the emerging data, treating such patients remains a challenge, and many treatments lack robust clinical evidence. We conducted a survey to evaluate Intensive Care Unit (ICU) management of COVID-19 patients with acute hypoxic respiratory failure and compared the results with data from a similar survey focusing on Acute Respiratory Distress Syndrome (ARDS) that was conducted in 2013.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The questionnaire was refined from a previous survey of ARDS-related clinical practice using an online electronic survey engine (Survey Monkey\u00ae) and all UK intensivists were encouraged to participate. The survey was conducted between 16\/05\/2020 and 17\/06\/2020.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were 137 responses from 89 UK centres. Non-invasive ventilation was commonly used in the form of CPAP. The primary ventilation strategy was the ARDSnet protocol, with 63% deviating from its PEEP recommendations. Similar to our previous ARDS survey, most allowed permissive targets for hypoxia (94%), hypercapnia (55%) and pH (94%). The routine use of antibiotics was common, and corticosteroids were frequently used, usually in the context of a clinical trial (45%). Late tracheostomy (&gt;7 days) was preferred (92%). Routine follow-up was offered by 66% with few centres providing routine dedicated rehabilitation programmes following discharge. Compared to the ARDS survey, there is an increased use of neuromuscular agents, APRV ventilation and improved provision of rehabilitation services.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Similar to our previous ARDS survey, this survey highlights variations in the management strategies used for patients with acute hypoxic respiratory failure due to COVID-19.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17511437211002352","type":"journal-article","created":{"date-parts":[[2021,3,15]],"date-time":"2021-03-15T16:59:02Z","timestamp":1615827542000},"page":"285-292","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Intensive care physicians\u2019 perceptions of the diagnosis &amp; management of patients with acute hypoxic respiratory failure associated with COVID-19: A UK based survey"],"prefix":"10.1177","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0165-3359","authenticated-orcid":false,"given":"Ahilanandan","family":"Dushianthan","sequence":"first","affiliation":[{"name":"Critical Care Research Group, Southampton National Institute of Health Research Biomedical Research Centre, University Hospital Southampton\/University of Southampton, Southampton, UK"},{"name":"Integrative Physiology and Critical Illness Group, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6257-207X","authenticated-orcid":false,"given":"Andrew F","family":"Cumpstey","sequence":"additional","affiliation":[{"name":"Critical Care Research Group, Southampton National Institute of Health Research Biomedical Research Centre, University Hospital Southampton\/University of Southampton, Southampton, UK"},{"name":"Integrative Physiology and Critical Illness Group, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Critical Care Research Group, Southampton National Institute of Health Research Biomedical Research Centre, University Hospital Southampton\/University of Southampton, Southampton, UK"},{"name":"Integrative Physiology and Critical Illness Group, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Thomas","sequence":"additional","affiliation":[{"name":"Critical Care Research Group, Southampton National Institute of Health Research Biomedical Research Centre, University Hospital Southampton\/University of Southampton, Southampton, UK"},{"name":"Integrative Physiology and Critical Illness Group, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramani S","family":"Moonesinghe","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Perioperative Medicine, University College Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Summers","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugh","family":"Montgomery","sequence":"additional","affiliation":[{"name":"Centre for Human Health and Performance, Department of Medicine, University College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael PW","family":"Grocott","sequence":"additional","affiliation":[{"name":"Critical Care Research Group, Southampton National Institute of Health Research Biomedical Research Centre, University Hospital Southampton\/University of Southampton, Southampton, UK"},{"name":"Integrative Physiology and Critical Illness Group, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK"},{"name":"Department of Anesthesiology, Duke University School of Medicine, Durham, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,3,15]]},"reference":[{"key":"bibr1-17511437211002352","unstructured":"WHO Timeline - COVID-19, www.who.int\/news-room\/detail\/27-04-2020-who-timeline\u2013-covid-19 (accessed 8 May 2020)."},{"key":"bibr2-17511437211002352","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30566-3"},{"key":"bibr3-17511437211002352","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.4031"},{"key":"bibr4-17511437211002352","unstructured":"GOV.UK Coronavirus (COVID-19 in the UK), https:\/\/coronavirus.data.gov.uk\/details\/healthcare (accessed 22 December 2020)."},{"key":"bibr5-17511437211002352","unstructured":"These data arise from the ICNARC Case Mix Programme Database. The case mix programme is the national clinical audit of patient outcomes from adult critical care coordinated by the Intensive Care National Audit & Research Centre (ICNARC), www.icnarc.org\/Our-Audit\/Audits\/Cmp\/Reports (accessed 22 December 2020)."},{"key":"bibr6-17511437211002352","unstructured":"National Guidance \u2013 ICM Anaesthesia COVID-19. Clinical guide for the management of critical care adults with COVID-19 during the coronavirus pandemic, https:\/\/icmanaesthesiacovid-19.org\/clinical-guide-for-the-management-of-critical-care-for-adults-with-covid-19-during-the-coronavirus-pandemic. (accessed 28 October 2020)."},{"key":"bibr7-17511437211002352","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-020-06033-2"},{"key":"bibr8-17511437211002352","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2020.06.013"},{"key":"bibr9-17511437211002352","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202008-3212OC"},{"key":"bibr10-17511437211002352","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2253-14-87"},{"key":"bibr11-17511437211002352","unstructured":"These data arise from the ICNARC Case Mix Programme Database, CMP Participating Units, www.icnarc.org\/Our-Audit\/Audits\/Cmp\/About\/Participation (accessed 14 September 2020)."},{"key":"bibr12-17511437211002352","unstructured":"These data arise from the Scottish Intensive Care Society Audit Group, SICSAG Participating Units, www.sicsag.scot.nhs.uk\/About\/Participants.html (accessed 14 September 2020)."},{"key":"bibr13-17511437211002352","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2021436"},{"key":"bibr14-17511437211002352","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.17022"}],"container-title":["Journal of the Intensive Care Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17511437211002352","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/17511437211002352","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17511437211002352","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:54:38Z","timestamp":1777460078000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/17511437211002352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,15]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["10.1177\/17511437211002352"],"URL":"https:\/\/doi.org\/10.1177\/17511437211002352","relation":{},"ISSN":["1751-1437"],"issn-type":[{"value":"1751-1437","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3,15]]}}}