{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T02:34:46Z","timestamp":1781922886313,"version":"3.54.5"},"reference-count":33,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T00:00:00Z","timestamp":1631750400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Intensive Care Society"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Right ventricular (RV) function is increasingly being recognised as an important factor influencing outcomes in ST elevation myocardial infarction (STEMI) complicated by cardiogenic shock (CS). In this study, we investigated RV echocardiographic parameters\u2019 association with 28-day mortality in patients admitted to intensive care with STEMI complicated by CS with reduced left ventricle ejection fraction (LVEF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>We performed a retrospective analysis of patients admitted to intensive care unit (ICU) in a single tertiary cardiac centre over a 34-month period with STEMI complicated by CS and LVEF &lt; 40%. Clinical and echocardiographic data were collected and correlated with 28-day mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>One-hundred patients were included with a mean age of 62.6 \u00b112.7 years and 78% were male. Mortality at 28 days was 37%. Respectively, 85%, 40% and 25% of patients required mechanical ventilation, mechanical circulatory support and renal replacement therapy. Tricuspid annulus peak systolic velocity (RV S\u2019) was significantly higher in survivors (12 \u00b1 3.3 v 10 \u00b1 3.5\u00a0cm\/s, p = 0.03) and was an independent predictor of mortality (odds ratio 1.2, 95% confidence interval 1.1\u20131.4, p = 0.04). RV S\u2019 of 10.5\u00a0cm\/s exhibited best sensitivity and specificity (64% and 65%, respectively; p = 0.02) for mortality. The Kaplan\u2013Meier curve demonstrated 85% risk of 28-day mortality for RV S\u2019 &lt; 10.5\u00a0cm\/s v 53% for RV S\u2019 &gt; 10.5\u00a0cm\/s ( p = 0.02).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>RV function is associated 28-day mortality in patients admitted to ICU with STEMI complicated by CS with reduced LVEF. RV S\u2019 predicted mortality with good sensitivity and specificity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17511437211037927","type":"journal-article","created":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T02:06:14Z","timestamp":1631844374000},"page":"439-446","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Right ventricular function is associated with 28-day mortality in myocardial infarction complicated by cardiogenic shock: A retrospective observational study"],"prefix":"10.1177","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5630-3065","authenticated-orcid":false,"given":"Hazem","family":"Lashin","sequence":"first","affiliation":[{"name":"Adult Critical Care Unit, Barts Heart Centre, St Bartholomew\u2019s Hospital, West Smithfield, London, UK"},{"name":"William Harvey Research Institute, Barts and the London school of medicine and dentistry, Queen Mary University of London, Charterhouse square, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olusegun","family":"Olusanya","sequence":"additional","affiliation":[{"name":"Adult Critical Care Unit, Barts Heart Centre, St Bartholomew\u2019s Hospital, West Smithfield, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeev","family":"Bhattacharyya","sequence":"additional","affiliation":[{"name":"William Harvey Research Institute, Barts and the London school of medicine and dentistry, Queen Mary University of London, Charterhouse square, London, UK"},{"name":"Cardiology Department Barts Heart Centre, St Bartholomew\u2019s Hospital, West Smithfield, London, 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