{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:06:59Z","timestamp":1777853219315,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2020,1,24]],"date-time":"2020-01-24T00:00:00Z","timestamp":1579824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Hand Surg Eur Vol"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:p>The aim of this study was to determine whether recurrent Dupuytren\u2019s disease after collagenase Clostridium histolyticum treatment differs histologically from recurrence in those treated with fasciectomy. We carried out a prospective cohort study of patients with Dupuytren\u2019s disease who underwent fasciectomy to treat disease recurrence after previous treatment with collagenase Clostridium histolyticum or fasciectomy. The pathologists and statistician were blinded to the previous treatment. Longitudinal biopsy sections were stained with haematoxylin-eosin and the nodular zones were examined. Fifteen patients were studied: nine previously treated with collagenase Clostridium histolyticum and six previously treated with fasciectomy. There were no histological differences between the samples from the two groups of patients. Dupuytren\u2019s disease recurrences after fasciectomy and collagenase Clostridium histolyticum are histologically indistinguishable.<\/jats:p>","DOI":"10.1177\/1753193419900483","type":"journal-article","created":{"date-parts":[[2020,1,24]],"date-time":"2020-01-24T23:28:25Z","timestamp":1579908505000},"page":"508-512","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Recurrent Dupuytren\u2019s disease after fasciectomy and collagenase injection are histologically indistinguishable"],"prefix":"10.1177","volume":"45","author":[{"given":"Rafael","family":"Sanjuan-Cervero","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery and Traumatology, Hospital de Denia, Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco J.","family":"Carrera-Hueso","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Hospital Dr. Moliner, Serra, Valencia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Vaquero-Perez","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital de Denia, Alicante, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Montaner-Alonso","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery and Traumatology, Hospital Universitario Dr. Peset, Valencia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,1,24]]},"reference":[{"key":"bibr1-1753193419900483","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2016.03.003"},{"key":"bibr2-1753193419900483","unstructured":"Dako EGFR pharmDx\u2122 Interpretation Manual \u2013 Agilent. https:\/\/www.agilent.com\/cs\/library\/usermanuals\/public\/08052_egfr_pharmdx_interpretation_manual.pdf. 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