{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T01:00:31Z","timestamp":1787792431877,"version":"build-2784847793"},"reference-count":29,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T00:00:00Z","timestamp":1631750400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Hand Surg Eur Vol"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:p>In this prospective cohort study, the health-related quality of life (HRQoL) from a societal perspective of carpal tunnel syndrome (CTS) patients was determined and compared with other diseases. In addition, the effect of carpal tunnel release (CTR) was analysed 6\u00a0weeks postoperatively with regard to mean EQ-5D index value improvement, side-effects of surgery and cost per quality adjusted life year (QALY) gained. We found a baseline mean EQ-5D index value of 0.75 (SD: 0.23), comparable with values seen in other disease like breast cancer, diabetes and asthma. Furthermore, we found that CTR improved HRQoL substantially 6\u00a0weeks postoperatively (mean\u2009+\u20090.12, SD: 0.22) and significantly reduced symptom reporting (mean \u221252%, SD: 53) with a cost per QALY gained of \u20ac396.05. In conclusion, CTS has a comparable impact on quality of life as compared with other diseases, and CTR has the potential to substantially improve patient\u2019s HRQoL at a fairly modest cost.<\/jats:p>\n                  <jats:p>Level of evidence: III<\/jats:p>","DOI":"10.1177\/17531934211045634","type":"journal-article","created":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T04:23:34Z","timestamp":1631766214000},"page":"347-352","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["The effect of carpal tunnel release on health-related quality of life of 2346 patients over a 5-year period"],"prefix":"10.1177","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3175-9653","authenticated-orcid":false,"given":"Justin D.","family":"Postma","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery, Martini Hospital, Groningen, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0306-1565","authenticated-orcid":false,"given":"Marius A.","family":"Kemler","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Martini Hospital, Groningen, Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,9,16]]},"reference":[{"key":"bibr1-17531934211045634","doi-asserted-by":"publisher","DOI":"10.1053\/jhsu.2002.35083"},{"key":"bibr2-17531934211045634","first-page":"1668","volume":"97","author":"Atroshi I","year":"2000","journal-title":"Lakartidningen"},{"key":"bibr3-17531934211045634","doi-asserted-by":"publisher","DOI":"10.1023\/A:1013171831202"},{"key":"bibr4-17531934211045634","doi-asserted-by":"publisher","DOI":"10.1177\/0272989X0002000409"},{"key":"bibr5-17531934211045634","doi-asserted-by":"publisher","DOI":"10.4236\/abcr.2018.72011"},{"key":"bibr6-17531934211045634","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511996214"},{"key":"bibr7-17531934211045634","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199711000-00002"},{"key":"bibr8-17531934211045634","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-57010-5"},{"key":"bibr9-17531934211045634","unstructured":"EuroQol. 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