{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:03:35Z","timestamp":1777853015839,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,10,13]],"date-time":"2024-10-13T00:00:00Z","timestamp":1728777600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,10,13]],"date-time":"2024-10-13T00:00:00Z","timestamp":1728777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Hand Surg Eur Vol"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p>\n                    The purpose of this study was to assess the effect of dexmedetomidine as a local anaesthetic adjuvant on flap blood flow and patient satisfaction regarding postoperative analgesia anterolateral thigh free flap transfer for hand trauma. A total of 66 patients were randomized into two groups. One group was treated with intermittent 1.0\u2009\u00b5g\/mL dexmedetomidine\u2009+\u20090.125% ropivacaine bolus at 8\u2009mL\/2\u2009h and the other with intermittent 0.2% ropivacaine bolus at 8\u2009mL\/2\u2009h, administered via continuous infraclavicular brachial plexus block. Dexmedetomidine had no significant effect on the flap blood supply and had a good safety profile. Moreover, 1.0\u2009\u00b5g\/mL dexmedetomidine\u2009+\u20090.125% ropivacaine provided similar satisfactory postoperative analgesia as 0.2% ropivacaine (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&gt;\u20090.05), reduced hand numbness and motor block, and improved patient satisfaction (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&lt;\u20090.05). All the flaps in the dexmedetomidine\u2009+\u2009ropivacaine group and 30 of 31 flaps in the ropivacaine group survived. The addition of dexmedetomidine to the local anaesthetic infusion appears to be a safe method of improving postoperative symptoms.\n                  <\/jats:p>\n                  <jats:sec>\n                    <jats:title>Level of evidence:<\/jats:title>\n                    <jats:p>I<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17531934241281649","type":"journal-article","created":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T02:39:01Z","timestamp":1728873541000},"page":"523-530","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of dexmedetomidine combined with ropivacaine block on flap blood flow and patient satisfaction after flap transfer for hand trauma: a randomized controlled trial"],"prefix":"10.1177","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1270-1309","authenticated-orcid":false,"given":"Jinsong","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Ningbo No. 6 Hospital, Ningbo, Zhejiang, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xionghui","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Ningbo No. 6 Hospital, Ningbo, Zhejiang, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhou","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Ningbo No. 6 Hospital, Ningbo, Zhejiang, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peijun","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Ningbo No. 6 Hospital, Ningbo, Zhejiang, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yeying","family":"Ge","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Ningbo No. 6 Hospital, Ningbo, Zhejiang, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Hand Surgery, Ningbo No. 6 Hospital, Ningbo, Zhejiang, PR China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,10,13]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000000983"},{"key":"e_1_3_4_3_1","first-page":"7005","article-title":"Can anterolateral thigh flap be a rescuer in lower extremity injuries?","volume":"27","author":"Atilgan N","year":"2023","unstructured":"Atilgan N, Ipek B, Duman N, Orhan O, Yilmaz M. Can anterolateral thigh flap be a rescuer in lower extremity injuries? Eur Rev Med Pharmacol Sci. 2023, 27: 7005\u201311.","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000001006"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e318221fcc9"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-019-0843-2"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000002014"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2016.11.011"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000001581"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2021.637547"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200011000-00030"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/2010224"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.3344\/kjp.2016.29.1.29"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aep195"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e3181d6929d"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(00)00513-7"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1621726"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/8858312"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.4103\/0259-1162.176404"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aew411"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2008.01.014"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.122.001399"}],"container-title":["Journal of Hand Surgery (European Volume)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17531934241281649","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/17531934241281649","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17531934241281649","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:46:54Z","timestamp":1777502814000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/17531934241281649"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,13]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1177\/17531934241281649"],"URL":"https:\/\/doi.org\/10.1177\/17531934241281649","relation":{},"ISSN":["1753-1934","2043-6289"],"issn-type":[{"value":"1753-1934","type":"print"},{"value":"2043-6289","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,13]]}}}