{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T15:50:10Z","timestamp":1791993010207,"version":"4.4.0"},"reference-count":42,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ther Adv Respir Dis"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Although the 6-min walk test (6MWT) is the gold standard for assessing exercise-induced impairment of gas exchange, it cannot easily be performed in a clinical office environment. The aim of this study was to compare the 1-min sit-to-stand test (1STST) with the 6MWT for the ability to assess exercise-induced oxygen desaturation in patients with interstitial lung diseases (ILDs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      A total of 107 patients were enrolled and classified into three groups: sarcoidosis, fibrotic idiopathic interstitial pneumonia (f-IIP), and other forms of ILD. The 6MWT and 1STST were performed on the same day, and pulmonary function tests, pulse oxygen saturation (SpO\n                      <jats:sub>2<\/jats:sub>\n                      ), and dyspnea and fatigue (modified Borg scale) were assessed. SpO\n                      <jats:sub>2<\/jats:sub>\n                      desaturation was evaluated by intraclass correlation coefficient (ICC), Bland\u2013Altman analysis, and kappa (\u03ba) coefficient in the whole population and the patient subgroups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The SpO\n                      <jats:sub>2<\/jats:sub>\n                      nadir during the 1STST and 6MWT showed good consistency [mean \u00b1 standard deviation: 92.5% \u00b1 5% and 90% \u00b1 7%, respectively; ICC 0.77, 95% confidence interval (CI) 0.71\u20130.83] and correlated strongly ( r = 0.9, p &lt; 0.0001). The frequency of patients with oxygen desaturation \u2a7e4% was also consistent for the two exercise tests ( \u03ba = 0.68, 95% CI 0.54\u20130.82). The number of repetitions in the 1STST correlated with the 6MWT distance ( r = 0.5, p &lt; 0.0001), but the dyspnea scores were higher during the 1STST than the 6MWT ( p &lt; 0.0001). These findings did not differ for the three patient subgroups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The 1STST can measure exercise-induced desaturation in ILD patients and could be used as an alternative test to the 6MWT in office practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1753466618793028","type":"journal-article","created":{"date-parts":[[2018,8,9]],"date-time":"2018-08-09T09:40:19Z","timestamp":1533807619000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":96,"title":["The 1-minute sit-to-stand test to detect exercise-induced oxygen desaturation in patients with interstitial lung disease"],"prefix":"10.1177","volume":"12","author":[{"given":"Justine","family":"Briand","sequence":"first","affiliation":[{"name":"CHU Lille, Service de Pneumologie et Immuno-Allergologie, Centre de Comp\u00e9tence des Maladies Pulmonaires Rares, F-59000 Lille, France University of Lille, F-59000 Lille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Behal","sequence":"additional","affiliation":[{"name":"University of Lille, F-59000 Lille, France CHU Lille, EA 2694, Sant\u00e9 Publique: Epid\u00e9miologie et Qualit\u00e9 des Soins, Unit\u00e9 de Biostatistiques, F-59000 Lille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Chenivesse","sequence":"additional","affiliation":[{"name":"CHU Lille, Service de Pneumologie et Immuno-Allergologie, Centre de Comp\u00e9tence des Maladies Pulmonaires Rares, F-59000 Lille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidwine","family":"W\u00e9meau-Stervinou","sequence":"additional","affiliation":[{"name":"CHU Lille, Service de Pneumologie et Immuno-Allergologie, Centre de 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