{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T07:58:23Z","timestamp":1770278303572,"version":"3.49.0"},"reference-count":20,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"New Key Subjects of Jiading District, Shanghai Municipality","award":["2017-ZD-03"],"award-info":[{"award-number":["2017-ZD-03"]}]},{"name":"Science and Technology Commission of Minhang District, Shanghai Municipality","award":["2019MHZ114"],"award-info":[{"award-number":["2019MHZ114"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ther Adv Respir Dis"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec><jats:title>Background:<\/jats:title><jats:p> Increased immunoglobulin E (IgE) is associated with lower respiratory tract infections. The study aimed to evaluate the association between IgE and the rate of bronchopneumonia-related readmission within 12 months in children. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> A total of 1099 children aged over 1 year with bronchopneumonia, from 1 January 2015 to 31 December 2016, were enrolled. Unplanned readmissions within 12 months after discharge were observed. Multivariate regression analysis was used to identify independent risk factors for rehospitalization. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> The rate of rehospitalization was 11.4% (125\/1099). Compared to the nonreadmission children, IgE levels, the proportion of children with asthma and hospitalization duration were significantly higher in the readmission children ( p &lt; 0.05). Compared to the children with normal IgE (\u2264 165 IU\/ml) levels, the risk of rehospitalization was significantly higher in children with abnormal IgE [odds ratio (OR) 1.781, 95% confidence interval (CI) 1.209\u20132.624, p = 0.004]. Children with IgE level more than three times the upper limit had even higher risks of readmission (OR 2.037, 95%CI 1.172\u20133.540, p = 0.012). Meanwhile, the risk of readmission in children with abnormal IgE combined with or without bronchial asthma was significantly higher (OR 2.548 and 1.918, 95% CI 1.490\u20134.358 and 1.218\u20133.020, p = 0.001 and 0.005, respectively). <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions:<\/jats:title><jats:p> Children aged over 1 year with bronchopneumonia who had higher IgE levels are at increased risk for rehospitalization within the first 12 months of the index hospitalization and IgE level may be used as a predictor of rehospitalization in children with bronchopneumonia. <\/jats:p><\/jats:sec>","DOI":"10.1177\/1753466619879832","type":"journal-article","created":{"date-parts":[[2019,10,7]],"date-time":"2019-10-07T06:30:10Z","timestamp":1570429810000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["High immunoglobulin E level is associated with increased readmission in children with bronchopneumonia"],"prefix":"10.1177","volume":"13","author":[{"given":"Cun","family":"You","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Minhang Branch, Zhongshan Hospital, Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guo","family":"Ran","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Wu","sequence":"additional","affiliation":[{"name":"Emergency Department, Jiading District Central Hospital Affiliated Shanghai University of Medicine and Health Sciences, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Wang","sequence":"additional","affiliation":[{"name":"Jiuting Town Community Healthcare Center of Songjiang District, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Tian","sequence":"additional","affiliation":[{"name":"Jiuting Town Community Healthcare Center of Songjiang District, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiabao","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, Minhang Branch, Zhongshan Hospital, Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zezhong","family":"Yao","sequence":"additional","affiliation":[{"name":"Department of pediatrics, Minhang Branch, Zhongshan Hospital, Fudan University, No.170, Xinsong Rd, Minhang, Shanghai 201199, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8908-5618","authenticated-orcid":false,"given":"Fei","family":"Wang","sequence":"additional","affiliation":[{"name":"Emergency Department, Jiading District Central Hospital Affiliated Shanghai University of Medicine & Health Sciences, No.1, Chengbei Rd, Jiading, Shanghai 201800, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,10,6]]},"reference":[{"key":"bibr1-1753466619879832","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0011721"},{"key":"bibr2-1753466619879832","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000001464"},{"key":"bibr3-1753466619879832","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-019-03552-9"},{"key":"bibr4-1753466619879832","doi-asserted-by":"publisher","DOI":"10.1159\/000488050"},{"key":"bibr5-1753466619879832","first-page":"192","volume":"116","author":"Robledo Aceves M","year":"2018","journal-title":"Arch Argent 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