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Many diseases, such as metabolic diseases, cancer, neurodegenerative diseases, and lung diseases, have been confirmed to be associated with elevated or impaired levels of autophagy. At present, studies have found that autophagy participates in the regulation of chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis, pulmonary hypertension, acute lung injury, lung cancer, and other pulmonary diseases. Using recent literature on the signal transduction mechanisms of autophagy and the effects of autophagy signalling on lung diseases, this review intends to clarify the mechanisms of lung disease to guide the treatment of related diseases. <\/jats:p><jats:p> The reviews of this paper are available via the supplemental material section. <\/jats:p>","DOI":"10.1177\/1753466619890538","type":"journal-article","created":{"date-parts":[[2019,11,27]],"date-time":"2019-11-27T08:19:17Z","timestamp":1574842757000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":80,"title":["Autophagy and pulmonary disease"],"prefix":"10.1177","volume":"13","author":[{"given":"Shi-xia","family":"Liao","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, Affiliated Hospital of ZunYi Medical College, Guizhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng-peng","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Osteopathy, Affiliated Hospital of ZunYi Medical College, Guizhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-hui","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Affiliated Hospital of ZunYi Medical College, Guizhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi-min","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Affiliated Hospital of ZunYi Medical College, Guizhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan-ying","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Affiliated Hospital of ZunYi Medical College, Guizhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2649-6951","authenticated-orcid":false,"given":"Yao","family":"Ou-Yang","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Affiliated Hospital of ZunYi Medical College, 201 Daliang Road, Zunyi City, Guizhou 563003, P.R. 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