{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T09:01:02Z","timestamp":1776934862263,"version":"3.51.2"},"reference-count":38,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ther Adv Respir Dis"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      Bronchoscopic lung volume reduction (BLVR)\n                      <jats:italic toggle=\"yes\">via<\/jats:italic>\n                      valve implantation can be achieved by targeting severely hyperinflated and emphysematously destructed lung areas in patients with chronic obstructive lung disease. Lack of collateral ventilation (CV) is important for good outcomes with BLVR. CV can be measured using the catheter-based Chartis system. The aim of this study was to evaluate the correlation between total exhaled volume drained from the target lobe measured by Chartis and clinical outcomes after BLVR in CV-negative patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      From January 2016 to March 2019, 60 patients were included in this retrospective single-center analysis. Drained volume (TVol) measured by Chartis was recorded and compared with lung function and physical performance parameters. Outcome variables included the percentage change in lung function [forced expiratory volume in 1\u2009s (FEV\n                      <jats:sub>1<\/jats:sub>\n                      ), residual volume (RV), and inspiratory vital capacity (IVC)]. Secondary outcomes were the degree of target lobe volume reduction (TLVR), change in 6-min walk distance (6MWD), and change in chronic obstructive pulmonary disease (COPD) assessment test (CAT) score.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Drained volume correlated significantly with post-BLVR change in FEV\n                      <jats:sub>1<\/jats:sub>\n                      (\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      \u2009=\u20090.663), IVC (\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      \u2009=\u20090.611), RV (\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      \u2009=\u2009\u22120.368), and TLVR (\n                      <jats:italic toggle=\"yes\">r<\/jats:italic>\n                      \u2009=\u20090.635) (all\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.05). In\n                      <jats:italic toggle=\"yes\">a priori<\/jats:italic>\n                      -defined patient subgroups based on drained volume [&lt;100\u2009ml (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200919), 100\u2212400\u2009ml (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200933), and &gt;400\u2009ml (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u20098)]; mean changes in FEV\n                      <jats:sub>1<\/jats:sub>\n                      were 2.6%, 17.4%, and 51.3%; in RV were \u22123.9%, \u221210.6%, and \u221223.8%; in IVC were \u22124.0%, 10.6%, and 62.4%; and in TLVR were 525\u2009ml (39%), 1375\u2009ml (73%) and 1760\u2009ml (100%), respectively. There were no significant correlations between absolute and percentage changes in 6MWD and the CAT score. Lung volume reduction was diagnosed in 32 (53%) cases.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Drained volume measured by the Chartis system correlated with functional improvement in CV-negative patients undergoing BLVR.<\/jats:p>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">The reviews of this paper are available via the supplemental material section.<\/jats:italic>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1753466620932507","type":"journal-article","created":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T22:48:20Z","timestamp":1593730100000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Predictive value of Chartis measurement for lung function improvements in bronchoscopic lung volume reduction"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5841-8181","authenticated-orcid":false,"given":"Johannes","family":"Wienker","sequence":"first","affiliation":[{"name":"Department of Pneumology, Division of Interventional Pneumology, University Medicine Essen-Ruhrlandklinik, T\u00fcschener Weg 40, Essen, NRW 45239, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00fcdiger","family":"Karpf-Wissel","sequence":"additional","affiliation":[{"name":"Department of Pneumology, University Medicine Essen-Ruhrlandklinik, Essen, Nordrhein-Westfalen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faustina","family":"Funke","sequence":"additional","affiliation":[{"name":"Department of Pneumology, University Medicine Essen-Ruhrlandklinik, Essen, Nordrhein-Westfalen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Taube","sequence":"additional","affiliation":[{"name":"Department of Pneumology, University Medicine Essen-Ruhrlandklinik, Essen, Nordrhein-Westfalen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"W\u00e4lscher","sequence":"additional","affiliation":[{"name":"Department of Pneumology, University Medicine Essen-Ruhrlandklinik, Essen, Nordrhein-Westfalen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane","family":"Winantea","sequence":"additional","affiliation":[{"name":"Department of Pneumology, University Medicine Essen-Ruhrlandklinik, Essen, Nordrhein-Westfalen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Maier","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Nordrhein-Westfalen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khaled","family":"Mardanzai","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, University Medicine Essen-Ruhrlandklinik, Essen, Nordrhein-Westfalen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaid","family":"Darwiche","sequence":"additional","affiliation":[{"name":"Department of Pneumology, University Medicine Essen-Ruhrlandklinik, Essen, Nordrhein-Westfalen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,7,2]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/resp.12660"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201707-1327OC"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60001-0"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201607-1383OC"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1507807"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2018.02.69"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/1753466619866101."},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000453588"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivy340."},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000446288"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1159\/000500407"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/resp.12253"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201407-1205OC"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00015312"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0900928"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1159\/000448849"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1159\/000479379"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1159\/000360641"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1081\/COPD-200053377"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00219111"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2009.10.017"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(14)70001-3"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2013-203743"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.6261"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/resp.12819"},{"key":"e_1_3_3_27_2","first-page":"04","article-title":"Correlation between six minute walk test and spirometry in chronic pulmonary disease","volume":"9","author":"Agrawal MB","year":"2015","unstructured":"Agrawal MB, Awad NT. Correlation between six minute walk test and spirometry in chronic pulmonary disease. J Clin Diagn Res 2015; 9: OC01\u201304.","journal-title":"J Clin Diagn Res"},{"key":"e_1_3_3_28_2","first-page":"3053","article-title":"Relationship between 6-minute walk test and pulmonary function test in stable chronic obstructive pulmonary disease with different severities","volume":"125","author":"Chen H","year":"2012","unstructured":"Chen H, Liang BM, Tang YJ, et al. Relationship between 6-minute walk test and pulmonary function test in stable chronic obstructive pulmonary disease with different severities. Chin Med J 2012; 125: 3053\u20133058.","journal-title":"Chin Med J"},{"key":"e_1_3_3_29_2","article-title":"Six minute walk test: a tool for predicting mortality in chronic pulmonary diseases","volume":"11","author":"Karanth MS","year":"2017","unstructured":"Karanth MS, Awad NT. Six minute walk test: a tool for predicting mortality in chronic pulmonary diseases. J Clin Diagn Res 2017; 11: OC34\u2013OC38.","journal-title":"J Clin Diagn Res"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1097\/LBR.0000000000000527"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1159\/000452629"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1159\/000448761"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.91075.2008"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1097\/LBR.0b013e3181a40a3e"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1159\/000319441"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1159\/000442886"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01973-2015"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1159\/000490733"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S103807"}],"container-title":["Therapeutic Advances in Respiratory Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1753466620932507","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1753466620932507","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1753466620932507","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T01:09:11Z","timestamp":1767661751000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1753466620932507"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":38,"alternative-id":["10.1177\/1753466620932507"],"URL":"https:\/\/doi.org\/10.1177\/1753466620932507","relation":{},"ISSN":["1753-4666","1753-4666"],"issn-type":[{"value":"1753-4666","type":"print"},{"value":"1753-4666","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1]]},"article-number":"1753466620932507"}}