{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T04:06:23Z","timestamp":1772165183308,"version":"3.50.1"},"reference-count":66,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ther Adv Respir Dis"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background and objective:<\/jats:title>\n                    <jats:p>This study was performed to investigate the effect of expressive art therapy (EAT) on the health status of patients with chronic obstructive pulmonary disease (COPD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      This community-based cluster randomized controlled trial involved patients with COPD from 16 communities in China. Participants received either EAT plus usual care (UC) or UC only. General practitioners were trained in EAT before the intervention. The primary outcomes were depression and anxiety symptoms, measured with the Hospital Anxiety and Depression Scale (HADS) and expressed as the HADS score for depression or anxiety (HADS-D or HADS-A, respectively). The secondary outcomes were the quality of life and dyspnoea, measured with the COPD assessment test (CAT). Dyspnoea was assessed using the modified Medical Research Council (mMRC) dyspnoea scale. Lung function was expressed as the forced expiratory volume in 1\u2009s as a percentage of the predicted value [FEV\n                      <jats:sub>1<\/jats:sub>\n                      (% pred)]. Outcome data were collected from all participants at baseline, 2 and 6\u2009months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      In total, 360 participants with COPD and comorbid depression were included in the analysis with the control group of 181 receiving UC only and the intervention group of 179 receiving EAT plus UC. The EAT group showed significantly greater improvement in the HADS-D and HADS-A scores than the UC group at 2\u2009months ( p\u2009&lt;\u20090.0001 and p\u2009&lt;\u20090.001, respectively) and 6\u2009months ( p\u2009&lt;\u20090.001 for both). The CAT and mMRC scores were significantly lower in the EAT group than in the UC group at 2 and 6\u2009months ( p\u2009&lt;\u20090.001 for all). The FEV\n                      <jats:sub>1<\/jats:sub>\n                      (% pred) was significantly higher in the EAT group than in the UC group at 6\u2009months ( p\u2009&lt;\u20090.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>General practitioners can deliver EAT interventions. EAT can effectively reduce anxiety and depression symptoms and dyspnoea, improve quality of life and improve the pulmonary function of patients with COPD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17534666221111876","type":"journal-article","created":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T03:30:50Z","timestamp":1658201450000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Effects of expressive art therapy on health status of patients with chronic obstructive pulmonary disease: a community-based cluster randomized controlled trial"],"prefix":"10.1177","volume":"16","author":[{"given":"Xiaowei","family":"Zuo","sequence":"first","affiliation":[{"name":"Department of Psychiatry, The Affiliated Xuzhou Oriental Hospital of Xuzhou Medical University, Xuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peian","family":"Lou","sequence":"additional","affiliation":[{"name":"Department of Control and Prevention of Chronic Non-Communicable Diseases, Xuzhou Center for Disease Control and Prevention, Xuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanan","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bi","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianghua","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, The Affiliated Xuzhou Oriental Hospital of Xuzhou Medical University, Xuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peipei","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Control and Prevention of Chronic Non-Communicable Diseases, Xuzhou Center for Disease Control and Prevention, Xuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zongmei","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Control and Prevention of Chronic Non-Communicable Diseases, Xuzhou Center for Disease Control and Prevention, Xuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuan","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Control and Prevention of Chronic Non-Communicable Diseases, Xuzhou Center for Disease Control and Prevention, Xuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ting","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Control and Prevention of Chronic Non-Communicable Diseases, Xuzhou Center for Disease Control and Prevention, Xuzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6097-4067","authenticated-orcid":false,"given":"Pan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Control and Prevention of Chronic Non-Communicable Diseases, Xuzhou Center for Disease Control and Prevention, 142 West Erhuan Road, Xuzhou 221006, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,7,19]]},"reference":[{"key":"bibr1-17534666221111876","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31222-9"},{"key":"bibr2-17534666221111876","doi-asserted-by":"publisher","DOI":"10.1016\/j.arbres.2017.02.001"},{"key":"bibr3-17534666221111876","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32335-3"},{"key":"bibr4-17534666221111876","unstructured":"WHO. 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