{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T04:06:24Z","timestamp":1772165184229,"version":"3.50.1"},"reference-count":21,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ther Adv Respir Dis"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>\n                    Bronchial lipoma is a rare benign tumor of the lung, which is often misdiagnosed due to concomitant pulmonary diseases. In addition, the coexistence of endobronchial lipoma and lung cancer is extremely unusual. To date, no related computed tomography (CT) images have been reported. The patient was a 53-year-old man, who was admitted to our hospital with cough, yellow phlegm, and fever for 1\u2009week. The CT image showed an irregular mass in the medial segment of the right middle lobe (B\n                    <jats:sup>4a<\/jats:sup>\n                    ) with surrounding ground glass opacity, and another solid nodule in the right lower lobe (B\n                    <jats:sup>6b<\/jats:sup>\n                    ). Unfortunately, after 2\u2009weeks of anti-inflammatory treatment, the bronchial invasion of the B\n                    <jats:sup>4a<\/jats:sup>\n                    nodule did not decrease significantly, so further bronchoscopy was carried out and tumor resection was performed using endoscopic mucosal resection with a ligation device (EMR-L). During the follow-up 4\u2009months, it was found that the B\n                    <jats:sup>6b<\/jats:sup>\n                    nodule was marked enlargement and then removed. The lesions of the B\n                    <jats:sup>4a<\/jats:sup>\n                    and B\n                    <jats:sup>6b<\/jats:sup>\n                    were confirmed as endobronchial lipoma and squamous cell carcinoma (T1aN0M0) by histopathology and immunohistochemical staining, respectively, and no postoperative radiotherapy or chemotherapy was performed. Regrettably, after 29\u2009months of follow-up, we observed recurrence and slow enlargement of the lipoma in its original location, progressive emphysema in both lungs, and solitary chest wall metastasis from the B\n                    <jats:sup>6b<\/jats:sup>\n                    squamous cell carcinoma that had been resected. Therefore, endobronchial endoscopy resection should be carefully selected for larger endobronchial lipoma. If it is accompanied by early squamous cell carcinoma (T1aN0M0), we still recommend active postoperative chemoradiotherapy.\n                  <\/jats:p>","DOI":"10.1177\/17534666231208575","type":"journal-article","created":{"date-parts":[[2023,10,27]],"date-time":"2023-10-27T04:53:21Z","timestamp":1698382401000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["An unexpected encounter and outcome between endobronchial lipoma and carcinoma: a case report and literature review"],"prefix":"10.1177","volume":"17","author":[{"given":"Yang","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Radiology, Tongde Hospital of Zhejiang Province, Hangzhou, China"},{"name":"Department of Radiology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tongde Hospital of Zhejiang Province, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Songkuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiology, Tongde Hospital of Zhejiang Province, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangzhao","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Tongde Hospital of Zhejiang Province, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guoqun","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Radiology, Tongde Hospital of Zhejiang Province, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyu","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tongde Hospital of Zhejiang Province, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1194-9046","authenticated-orcid":false,"given":"Jian","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Tongde Hospital of Zhejiang Province, Hangzhou 310012, China"},{"name":"Number 234, Road Gucui, Hangzhou, Zhejiang Province, 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