{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T04:06:27Z","timestamp":1772165187609,"version":"3.50.1"},"reference-count":15,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ther Adv Respir Dis"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Self-expandable metallic stents (SEMS) are increasingly used in the management of both malignant and nonmalignant airway stenosis. There are multiple stents available in the market; however, the current literature on the efficacy and safety of newly available 3rd generation SEMS (Bonastent) is extremely limited and only has data from single center studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To report the efficacy and early (&lt;7\u2009days) and late (\u2a7e7\u2009days) complications in patients with central airway obstruction (CAO) treated with Bonastent placement at two institutions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>We performed a retrospective analysis of data of consecutive patients who underwent therapeutic bronchoscopy and Bonastent placement at two tertiary care university hospitals between January 2019 and November 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Bonastent deployment was performed in the operating room. Stents were deployed using rigid or flexible bronchoscopy under direct visualization with a flexible bronchoscope and in conjunction with fluoroscopic guidance. We then analyzed the effectiveness, short-term, and long-term complications of Bonastent placement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 107 Bonastents\u00ae were placed in 96 patients. The most common etiology of CAO was malignancy, 92.7% ( n\u2009=\u200989), followed by excessive dynamic airway collapse (EDAC) and post-intubation tracheal stenosis. Seventy-three patients (76%) had improvement in symptoms or imaging within 7\u2009days of stent placement, including successful liberation from mechanical ventilation in a patient with CAO. Early complications occurred in seven patients (two-airway bleeding, two-mucus plugging that improved with airway clearance, two-stent migrations, and one-cough). Late complications occurred in 23 patients (1-stent migration requiring revision bronchoscopy and replacement of airway stent, 11-mucus plugging, 6-granulation tissue, 2-pneumonia, 1-cough, 1-tumor ingrowth\/stent fracture, 1-airway emergency due to excessive granulation tissue obstructing the distal end of the stent and had a failed cricothyroidotomy leading to death). Overall, the early complication rate was 7.3% (7\/96) and late complication rate was 23.9% (23\/96).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our study is the first multicenter study that found a good safety profile with a low complication rate after tracheobronchial Bonastent placement with improvement in symptoms soon after stent placement.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17534666241260235","type":"journal-article","created":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T07:10:51Z","timestamp":1726816251000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["A multicenter observational study assessing the safety, feasibility, and complications of Bonastent in central airway obstruction"],"prefix":"10.1177","volume":"18","author":[{"given":"Nagendra Y.","family":"Madisi","sequence":"first","affiliation":[{"name":"Department of Medicine, Pulmonary & Critical Care Medicine, Albany Medical Center, 16 New Scotland Avenue, Albany, NY 12208, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0270-689X","authenticated-orcid":false,"given":"Sana","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Medicine, Pulmonary & Critical Care Medicine, Albany Medical Center, Albany, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Greenberg","sequence":"additional","affiliation":[{"name":"Department of Medicine, Pulmonary & Critical Care Medicine, Albany Medical Center, Albany, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gowthami","family":"Kobbari","sequence":"additional","affiliation":[{"name":"Department of Medicine, Pulmonary & Critical Care Medicine, Albany Medical Center, Albany, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad","family":"Salick","sequence":"additional","affiliation":[{"name":"Department of Medicine, Pulmonary & Critical Care Medicine, Albany Medical Center, Albany, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anoosh","family":"Parimi","sequence":"additional","affiliation":[{"name":"Department of Medicine, Internal Medicine, Albany Medical Center, Albany, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziad","family":"Boujaoude","sequence":"additional","affiliation":[{"name":"Department of Medicine, Interventional Pulmonology, Cooper University Hospital, Camden, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wissam","family":"Abouzgheib","sequence":"additional","affiliation":[{"name":"Department of Medicine, Interventional Pulmonology, Cooper University Hospital, Camden, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,9,20]]},"reference":[{"key":"bibr1-17534666241260235","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2016.02.001"},{"key":"bibr2-17534666241260235","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2017.07.27"},{"key":"bibr3-17534666241260235","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-2366"},{"key":"bibr4-17534666241260235","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14-1526"},{"key":"bibr5-17534666241260235","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14-1530"},{"key":"bibr6-17534666241260235","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2018.12.001"},{"key":"bibr7-17534666241260235","unstructured":"Thoracent Incorporated. Thoracent Bonastent tracheobronchial and esophageal stents, https:\/\/thoracent.com (2018, accessed 21 July 2023)."},{"key":"bibr8-17534666241260235","doi-asserted-by":"publisher","DOI":"10.1159\/000506815"},{"key":"bibr9-17534666241260235","doi-asserted-by":"publisher","DOI":"10.1097\/LBR.0000000000000567"},{"key":"bibr10-17534666241260235","doi-asserted-by":"publisher","DOI":"10.1097\/LBR.0000000000000603"},{"key":"bibr11-17534666241260235","doi-asserted-by":"publisher","DOI":"10.21037\/jtd-21-2003"},{"key":"bibr12-17534666241260235","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2007.11.008"},{"key":"bibr13-17534666241260235","doi-asserted-by":"publisher","DOI":"10.21037\/shc.2019.11.02"},{"issue":"6","key":"bibr14-17534666241260235","first-page":"430","volume":"93","author":"Fortin M","year":"2017","journal-title":"Espiration"},{"key":"bibr15-17534666241260235","doi-asserted-by":"publisher","DOI":"10.1007\/s002709900343"}],"container-title":["Therapeutic Advances in Respiratory Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17534666241260235","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/17534666241260235","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17534666241260235","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T02:41:27Z","timestamp":1738032087000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/17534666241260235"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":15,"alternative-id":["10.1177\/17534666241260235"],"URL":"https:\/\/doi.org\/10.1177\/17534666241260235","relation":{"has-review":[{"id-type":"doi","id":"10.1177\/17534666241260235\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/17534666241260235\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/17534666241260235\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/17534666241260235\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/17534666241260235\/v2\/decision1","asserted-by":"object"}]},"ISSN":["1753-4666","1753-4666"],"issn-type":[{"value":"1753-4666","type":"print"},{"value":"1753-4666","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"article-number":"17534666241260235"}}