{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T10:31:12Z","timestamp":1791973872324,"version":"4.4.0"},"reference-count":35,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"MSD Spain"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ther Adv Respir Dis"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Chronic cough (CC) has a negative effect on patients\u2019 quality of life and everyday activities. Emotional reactions are an important aspect of how patients deal with illness, and CC can lead to feelings of uncertainty, loss of control, helplessness, self-consciousness, embarrassment, worry, fear, frustration, irritability, and anger.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To assess the emotions related to bouts of cough in patients with refractory or unexplained chronic cough (RCC\/UCC), using a validated questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>This was a multicenter, non-interventional study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Patients with RCC\/UCC were recruited from hospital outpatient clinics in Spain. The impact of RCC\/UCC on patients\u2019 emotions was assessed using the self-reported Discrete Emotions Questionnaire (DEQ), which assesses eight distinct situationally induced state emotions, scored on a Likert scale from 1 to 7, with higher scores indicating that the emotion is experienced to a greater degree.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The survey was completed by 190 patients (148 women, 42 men; mean age 58.0\u2009years) of whom 120 had RCC and 70 had UCC (mean cough duration 6.3\u2009years). Highest mean (SD) scores were seen for the anger subscale (3.6 (1.7)) and anxiety subscale (3.3 (1.6), followed by the disgust (2.6 (1.5)), fear (2.6 (1.7)), and sadness (2.5 (1.5)) subscales. The same pattern was seen in subgroups by gender and by diagnosis (RCC or UCC). There were no significant differences in mean scores for any subscale between patients with RCC and those with UCC. Cough severity and the presence of cough-related stress urinary incontinence (SUI) were independently associated with negative emotion subscale scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Among patients with RCC\/UCC, bouts of cough triggered negative emotions such as anger, anxiety, disgust, fear, and sadness, as evaluated using a validated questionnaire. Results were similar for RCC and UCC. Increasing cough severity and the presence of SUI were independently associated with higher (worse) scores for negative emotions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17534666251374853","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T05:20:05Z","timestamp":1758691205000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Emotions in patients with refractory or unexplained chronic cough: a multicenter, non-interventional study"],"prefix":"10.1177","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7749-2838","authenticated-orcid":false,"given":"Ebymar","family":"Arismendi","sequence":"first","affiliation":[{"name":"Servicio de Neumolog\u00eda, Hospital Cl\u00ednic de Barcelona, Barcelona, IDIBAPS, Universitat de Barcelona, Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Raras (CIBERES), Instituto de Salud Carlos III de Madrid, all in Spain"},{"name":"Hospital Cl\u00ednic de Barcelona Carrer de Villarroel, 170, L\u2019Eixample, Barcelona 08036, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Puente-Maestu","sequence":"additional","affiliation":[{"name":"Servicio de Neumolog\u00eda, Hospital Universitario Gregorio Mara\u00f1\u00f3n, Facultad de Medicina de la UCM, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Domingo","sequence":"additional","affiliation":[{"name":"Servicio de Neumolog\u00eda, Hospital Parc Taul\u00ed, Sabadell, Barcelona, Spain"},{"name":"Departamento de Medicina, Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio","family":"D\u00e1vila","sequence":"additional","affiliation":[{"name":"Servicio de Alergolog\u00eda, Hospital Universitario de Salamanca, Departamento de Ciencias Biom\u00e9dicas y del 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