{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T04:06:30Z","timestamp":1772165190041,"version":"3.50.1"},"reference-count":26,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100012232","name":"National Key Clinical Specialty Discipline Construction Program of China","doi-asserted-by":"publisher","award":["grant 2011\u2013873"],"award-info":[{"award-number":["grant 2011\u2013873"]}],"id":[{"id":"10.13039\/501100012232","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ther Adv Respir Dis"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Subglottic cysts (SGCs) are a rare disease with a high misdiagnosis rate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>We aim to improve the diagnostic and management ability of pediatricians for SGCs by analyzing the clinical characteristics of confirmed cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Observational, retrospective cohort study<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We enrolled children diagnosed with SGCs admitted to the Children\u2019s Hospital of Chongqing Medical University between January 2010 and December 2022. Clinical characteristics data were collected and analyzed retrospectively. Patients were regularly followed up for 1 year post-treatment or discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Eleven children were included in this retrospective study. There were nine (9\/11, 81.8%) males and two (2\/11, 18.2%) females, and the median age was 15 months. Eight (72.7%) were premature. Seven (63.6%) patients had a history of intubation. The common manifestations were stridor (72.7%), wet cough (72.7%), shortness of breath (72.7%), and dyspnea (54.5%). The average diagnosis time was 7 months. The most common comorbidity was laryngopharyngeal reflux disease (LPRD, 45.5%), followed by laryngomalacia (27.3%), bronchopulmonary dysplasia (27.3%), bronchial stenosis (18.2%), and adenoid hypertrophy ( 18.2%). The obstruction degree of SGCs was \u201c3\u201d (51%\u201375% occlusion) or higher in eight (72.7%) patients. Two (18.2%) patients experienced recurrence after initial cyst aspiration and subsequently underwent successful laryngoscopy marsupialization. Ultimately, eight (72.7%) patients achieved complete recovery after endoscopic marsupialization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>SGCs should be considered in the differential diagnosis of children, especially those with a history of prematurity and\/or perinatal intubation, who present with stridor, wet cough, and respiratory distress. Endoscopic evaluation is crucial for both definitive diagnosis and guiding effective treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17534666251410167","type":"journal-article","created":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T06:36:00Z","timestamp":1767594960000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Subglottic cysts as an uncommon cause of upper airway obstruction: a 12-year retrospective study"],"prefix":"10.1177","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7200-4604","authenticated-orcid":false,"given":"Guangli","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, Children\u2019s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chongjie","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Children\u2019s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, No. 136 Zhongshan 2nd Rd, Yuzhong District, Chongqing 400010, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyin","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Children\u2019s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Children\u2019s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanyuan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Children\u2019s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengtao","family":"Suo","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Children\u2019s Hospital of Chongqing Medical University, Chongqing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Children\u2019s Hospital of Chongqing Medical University, Chongqing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruixue","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Children\u2019s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohong","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Children\u2019s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhengxiu","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Children\u2019s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, No. 136 Zhongshan 2nd Rd, Yuzhong District, Chongqing 400010, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,1,4]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2022-253750"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2020.110523"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-020-06321-z"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(02)00406-8"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.21053\/ceo.2023.00031"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.17116\/otorino20228803190"},{"key":"e_1_3_4_8_2","first-page":"1127","article-title":"A case of subglottic cyst through the cricothyroid membrane to the neck","volume":"57","author":"Zhou H","year":"2022","unstructured":"Zhou H, Li Q, Shi Q. A case of subglottic cyst through the cricothyroid membrane to the neck. Clin J Otorhinolaryngol Head Neck Surg 2022; 57: 1127\u20131129.","journal-title":"Clin J Otorhinolaryngol Head Neck Surg"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2024-261204"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/01455613241275317"},{"key":"e_1_3_4_11_2","first-page":"972","article-title":"Acquired subglottic cysts in infants with ultra-low birth weight: a case report","volume":"55","author":"Zhao XY","year":"2020","unstructured":"Zhao XY, Teng YS, Li ZN, et al. Acquired subglottic cysts in infants with ultra-low birth weight: a case report. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020; 55: 972\u2013974.","journal-title":"Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"e_1_3_4_12_2","first-page":"43","article-title":"Efficacy of endoscopic removal in the treatment of subglottic ductal cysts","volume":"33","author":"Jim\u00e9nez G\u00f3mez J","year":"2020","unstructured":"Jim\u00e9nez G\u00f3mez J, G\u00f3mez Cervantes JM, Encinas Hern\u00e1ndez JL, et al. Efficacy of endoscopic removal in the treatment of subglottic ductal cysts. Cir Pediatr 2020; 33: 43\u201346.","journal-title":"Cir Pediatr"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2006.11.014"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61602-X"},{"issue":"6","key":"e_1_3_4_15_2","first-page":"408","article-title":"Experts\u2019 consensus on the diagnosis and treatment of benign central airway stenosis via bronchoscopic interventional therapy","volume":"40","author":"The respiratory society of the Chineses Medical Association","year":"2017","unstructured":"The respiratory society of the Chineses Medical Association. Experts\u2019 consensus on the diagnosis and treatment of benign central airway stenosis via bronchoscopic interventional therapy. Clin J Tuberc Respir Dis 2017; 40(6): 408\u2013418.","journal-title":"Clin J Tuberc Respir Dis"},{"key":"e_1_3_4_16_2","first-page":"134","article-title":"Five cases of subglottic cysts","volume":"36","author":"Shuaishuai L","year":"2021","unstructured":"Shuaishuai L, Chao W, Yuan L, et al. Five cases of subglottic cysts. Clin J Appl Clin Pediatr 2021; 36: 134\u2013136.","journal-title":"Clin J Appl Clin Pediatr"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-021-07142-4"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2011.11.012"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2012.01.023"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2021.103280"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1972.02110170024003"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5876(87)90026-7"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(68)80434-2"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2010.12.005"},{"key":"e_1_3_4_25_2","first-page":"1149","article-title":"Experts consensus on diagnosis and treatment of laryngopharyngeal reflux disease (2022, revision)","volume":"57","author":"Subspecialty group of Laryngopharyngology, editorial board of Chinese journal of otorhinolaryngology head and neck surgery","year":"2022","unstructured":"Subspecialty group of Laryngopharyngology, editorial board of Chinese journal of otorhinolaryngology head and neck surgery. Experts consensus on diagnosis and treatment of laryngopharyngeal reflux disease (2022, revision). Clin J Otorhinolaryngol Head Neck Surg 2022; 57: 1149\u20131172.","journal-title":"Clin J Otorhinolaryngol Head Neck Surg"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27932"},{"key":"e_1_3_4_27_2","first-page":"1121","article-title":"Experts\u2019 consensus respiratory intervention and multidisciplinary collaboration for the diagnosis and treatment of pediatric central airway stenosis in China","volume":"36","author":"Experts group of pediatric respiratory endoscopy, talent exchange service center of national health commission endoscopy committee, pediatrics section of Chinese medical doctor association","year":"2021","unstructured":"Experts group of pediatric respiratory endoscopy, talent exchange service center of national health commission endoscopy committee, pediatrics section of Chinese medical doctor association. Experts\u2019 consensus respiratory intervention and multidisciplinary collaboration for the diagnosis and treatment of pediatric central airway stenosis in China. Clin J Appl Clin Pediatr 2021; 36: 1121\u20131137.","journal-title":"Clin J Appl Clin Pediatr"}],"container-title":["Therapeutic Advances in Respiratory Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17534666251410167","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/17534666251410167","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17534666251410167","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T17:30:11Z","timestamp":1769362211000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/17534666251410167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":26,"alternative-id":["10.1177\/17534666251410167"],"URL":"https:\/\/doi.org\/10.1177\/17534666251410167","relation":{"has-review":[{"id-type":"doi","id":"10.1177\/17534666251410167\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/17534666251410167\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/17534666251410167\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/17534666251410167\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/17534666251410167\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/17534666251410167\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/17534666251410167\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/17534666251410167\/v2\/decision1","asserted-by":"object"}]},"ISSN":["1753-4666","1753-4666"],"issn-type":[{"value":"1753-4666","type":"print"},{"value":"1753-4666","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"article-number":"17534666251410167"}}