{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T05:46:21Z","timestamp":1775713581689,"version":"3.50.1"},"reference-count":33,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2014,9,25]],"date-time":"2014-09-25T00:00:00Z","timestamp":1411603200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Obstet Med"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p> Neurological diseases remain the second most common cause of maternal mortality from indirect causes, according to the last United Kingdom confidential enquiry into maternal death. The maternal mortality rate from epilepsy is reported as 0.61 per 100,000 maternities. The aim of this study was to analyse the trends and causes of maternal death from epilepsy in the UK over the last 30 years. Information on sub-standard care associated with fatalities was also consolidated to inform guidance and clinical care by obstetricians and physicians caring for pregnant women with epilepsy. <\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p> A retrospective review of 10 triennial confidential enquiry into maternal death reports (1979\u20132008) was performed, encompassing 21,514,457 maternities. Late and coincidental deaths were not included in the analyses. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> Between 1979 and 2008, there were 92 maternal deaths from epilepsy. The proportion of total maternal deaths from epilepsy over 30 years is 3.7% (95% CI 3.0\u20134.5), which showed an increasing trend. Sudden unexpected death in epilepsy remains the single greatest cause of maternal death from epilepsy followed by aspiration of gastric contents during seizures and drowning during bathing. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p> All women with epilepsy should be looked after by specialist combined obstetric and medical or neurological teams in pregnancy to improve maternal and fetal outcomes. <\/jats:p><\/jats:sec>","DOI":"10.1177\/1753495x14553257","type":"journal-article","created":{"date-parts":[[2014,9,26]],"date-time":"2014-09-26T05:41:00Z","timestamp":1411710060000},"page":"160-164","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":22,"title":["Trends in maternal deaths from epilepsy in the United Kingdom: a 30-year retrospective review"],"prefix":"10.1177","volume":"7","author":[{"given":"Dipanwita","family":"Kapoor","sequence":"first","affiliation":[{"name":"Department of Obstetrics, Nottingham University Hospitals NHS Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne","family":"Wallace","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Nottingham University Hospitals NHS Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,9,25]]},"reference":[{"key":"bibr1-1753495X14553257","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2010.02847.x"},{"key":"bibr2-1753495X14553257","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.5.1270"},{"key":"bibr3-1753495X14553257","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1997.tb06130.x"},{"key":"bibr4-1753495X14553257","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(08)70202-3"},{"key":"bibr5-1753495X14553257","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(06)70448-3"},{"key":"bibr6-1753495X14553257","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1995.tb01061.x"},{"key":"bibr7-1753495X14553257","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.56.4.514"},{"key":"bibr8-1753495X14553257","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1997.tb01076.x"},{"key":"bibr9-1753495X14553257","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1996.tb00529.x"},{"key":"bibr10-1753495X14553257","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.2000.tb00208.x"},{"key":"bibr11-1753495X14553257","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1177\/014107689208501007","volume":"85","author":"Lip GYH","year":"1992","journal-title":"J R Soc Med"},{"key":"bibr12-1753495X14553257","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.67.4.439"},{"key":"bibr13-1753495X14553257","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2003.029132"},{"key":"bibr14-1753495X14553257","volume-title":"Report on confidential enquiries into maternal deaths in England and Wales 1979\u20131981","author":"Department of Health and Social Security","year":"1986"},{"key":"bibr15-1753495X14553257","volume-title":"Report on confidential enquiries into maternal deaths in England and Wales 1982\u20131984","author":"Department of Health and Social Security","year":"1989"},{"key":"bibr16-1753495X14553257","volume-title":"Report on confidential enquiries into maternal deaths in the United Kingdom, 1985\u20131987","author":"Department of Health","year":"1991"},{"key":"bibr17-1753495X14553257","volume-title":"Report on confidential enquiries into maternal deaths in the United Kingdom 1988\u20131990","author":"Department of Health","year":"1994"},{"key":"bibr18-1753495X14553257","volume-title":"Report on confidential enquiries into maternal deaths in the United Kingdom 1991\u20131993","author":"Department of Health","year":"1996"},{"key":"bibr19-1753495X14553257","volume-title":"Why mothers die. Report on confidential enquiries into maternal deaths in the United Kingdom 1994\u20131996","author":"Department of Health","year":"1998"},{"key":"bibr20-1753495X14553257","unstructured":"Lewis G, James D, et al. Why mothers die 1997\u20131999. In: Lewis G (ed.) The confidential enquiries into maternal deaths in the United Kingdom. London, UK: RCOG Press, 2001."},{"key":"bibr21-1753495X14553257","volume-title":"Why mothers die 2000\u20132002. In: Lewis G (ed.) The sixth report of the confidential enquiries into maternal deaths in the United Kingdom","author":"Lewis G","year":"2004"},{"key":"bibr22-1753495X14553257","volume-title":"Saving mothers\u2019 lives: reviewing maternal deaths to make motherhood safer \u2013 2003\u20132005. 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