{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T20:58:49Z","timestamp":1779310729047,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2016,6,21]],"date-time":"2016-06-21T00:00:00Z","timestamp":1466467200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Obstet Med"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> First-trimester care of maternal thyroid dysfunction has previously been shown to be poor. This study evaluates early management of thyroid dysfunction in pregnancy in Australia. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> Patients reviewed by the Obstetric Medicine team for thyroid dysfunction from 1 January 2012 to 30 June 2013 were included. Data were collected on gestation at referral from the patient\u2019s general practitioner to the antenatal clinic, information provided in the referral letter, thyroid function tests and thyroid medications. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> Eighty-five women were included in the study. At the time of general practitioner referral to antenatal services, 19% of women with preexisting thyroid disease had no thyroid function tested. Forty-three percent had an abnormal thyroid-stimulating hormone defined as being outside the laboratory-specific pregnancy reference range if available, or outside the level of 0.1\u20132.5\u2009mIu\/L in the first trimester, 0.2\u20133.0\u2009mIu\/L in the second trimester and 0.3\u20133.0\u2009mIu\/L in the third trimester. Only 21% of women increased their thyroxine dose prior to their first antenatal clinic review. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p> This study highlights that a significant proportion of women with known thyroid disease either have untested thyroid function in the first trimester or a thyroid-stimulating hormone outside of levels recommended by guidelines. <\/jats:p><\/jats:sec>","DOI":"10.1177\/1753495x16629773","type":"journal-article","created":{"date-parts":[[2016,4,15]],"date-time":"2016-04-15T00:43:49Z","timestamp":1460681029000},"page":"126-129","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Management of thyroid disease in pregnancy \u2013 Room for improvement in the first trimester"],"prefix":"10.1177","volume":"9","author":[{"given":"Helen","family":"Robinson","sequence":"first","affiliation":[{"name":"School of Medicine, Faculty of Medicine and Biomedical Sciences, University of Queensland, Queensland, Australia"},{"name":"Department of Internal Medicine and Aged Care, Royal Brisbane and Women\u2019s Hospital, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Robinson","sequence":"additional","affiliation":[{"name":"School of Medicine, Faculty of Medicine and Biomedical Sciences, University of Queensland, Queensland, Australia"},{"name":"Department of Rheumatology, Royal Brisbane and Women\u2019s Hospital Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"D\u2019Emden","sequence":"additional","affiliation":[{"name":"School of Medicine, Faculty of Medicine and Biomedical Sciences, University of Queensland, Queensland, Australia"},{"name":"Department of Endocrinology, Royal Brisbane and Women\u2019s Hospital, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kassam","family":"Mahomed","sequence":"additional","affiliation":[{"name":"School of Medicine, Faculty of Medicine and Biomedical Sciences, University of Queensland, Queensland, Australia"},{"name":"Department of Obstetrics and Gynaecology, Ipswich Hospital, Queensland, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,6,21]]},"reference":[{"key":"bibr1-1753495X16629773","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2011.0087"},{"key":"bibr2-1753495X16629773","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-2803"},{"key":"bibr3-1753495X16629773","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-07-0249"},{"key":"bibr4-1753495X16629773","first-page":"407","volume":"36","author":"Altomare M","year":"2013","journal-title":"J Endocrinol Invest"},{"key":"bibr5-1753495X16629773","first-page":"946","volume":"84","author":"Millar 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