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Early recognition and intervention is crucial in its management particularly with the recent availability of eculizumab, a humanized monoclonal antibody to complement component C5, which has demonstrated drastic improvement in prognosis. The issue, however, is arriving at a timely diagnosis given the considerable amount of overlap in the clinical and biochemical manifestation of P-aHUS, HELLP syndrome (haemolysis, elevated liver enzyme and low platelet count) and other hypertensive disorders of pregnancy. We present a case report and literature review that highlights the clinical conundrum of arriving at the diagnosis. We also highlight the importance of early management of P-aHUS with eculizumab and its impact on improving morbidity. <\/jats:p>","DOI":"10.1177\/1753495x17704563","type":"journal-article","created":{"date-parts":[[2017,5,18]],"date-time":"2017-05-18T12:10:09Z","timestamp":1495109409000},"page":"28-31","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Pregnancy-induced atypical haemolytic uremic syndrome: A new era with eculizumab"],"prefix":"10.1177","volume":"11","author":[{"given":"Renuka","family":"Shanmugalingam","sequence":"first","affiliation":[{"name":"Department of Renal Medicine, Liverpool Hospital, NSW, Australia"},{"name":"School of Medicine, Western Sydney University, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danny","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Haematology, Liverpool Hospital, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Makris","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine, Liverpool Hospital, NSW, Australia"},{"name":"School of Medicine, Western Sydney University, NSW, Australia"},{"name":"University of New South Wales, NSW, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,5,18]]},"reference":[{"key":"bibr1-1753495X17704563","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0902814"},{"key":"bibr2-1753495X17704563","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1182\/asheducation.V2012.1.617.3798924","volume":"2012","author":"Nester CM","year":"2012","journal-title":"Hematol Am Soc Hematol Educ Program"},{"key":"bibr3-1753495X17704563","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2009070706"},{"key":"bibr4-1753495X17704563","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1579539"},{"key":"bibr5-1753495X17704563","doi-asserted-by":"publisher","DOI":"10.1258\/om.2011.100059"},{"key":"bibr6-1753495X17704563","unstructured":"Mackaness CFF. 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