{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T05:39:05Z","timestamp":1771306745427,"version":"3.50.1"},"reference-count":25,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,7,26]],"date-time":"2018-07-26T00:00:00Z","timestamp":1532563200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Obstet Med"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:p> There is a paucity of data on pregnancy outcome in women living with a single kidney from all causes. Current thinking is extrapolated from living kidney donors, a group biased by strict selection criteria. We present a cohort of 26 women with a solitary functioning kidney; 11 women had an acquired single kidney of whom only 1 was a living donor and 15 had a congenital single kidney. Median time living with a single kidney was 28 years. None booked with hypertension or proteinuria. Urinary tract infection complicated 50% of pregnancies. Worryingly, 35% developed pre-eclampsia, gestational proteinuria or gestational hypertension. We propose pre-conceptual counselling, education on how to protect their single kidney, pre eclampsia prophylaxis with low-dose aspirin and close monitoring for urinary tract infection, hypertension and proteinuria with lower thresholds for pharmaceutical management. We have devised a Patient Information leaflet \u2013 \u2018Living with a single kidney, pregnancy and beyond\u2019. <\/jats:p>","DOI":"10.1177\/1753495x18784081","type":"journal-article","created":{"date-parts":[[2018,7,27]],"date-time":"2018-07-27T06:37:36Z","timestamp":1532673456000},"page":"22-26","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Pregnancy in women known to be living with a single kidney"],"prefix":"10.1177","volume":"12","author":[{"given":"Samantha EJ","family":"Steele","sequence":"first","affiliation":[{"name":"Department of Obstetrics, West Middlesex University Hospital, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jayne E","family":"Terry","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, St Mary\u2019s Hospital, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise M","family":"Page","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, West Middlesex University Hospital, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna C","family":"Girling","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, West Middlesex University Hospital, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,7,26]]},"reference":[{"key":"bibr1-1753495X18784081","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5001819"},{"key":"bibr2-1753495X18784081","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-145-3-200608010-00006"},{"key":"bibr3-1753495X18784081","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2013.460"},{"key":"bibr4-1753495X18784081","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-198512000-00015"},{"key":"bibr5-1753495X18784081","first-page":"308","volume":"25","author":"Jones JW","year":"1993","journal-title":"Transplant Proc"},{"key":"bibr6-1753495X18784081","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199612270-00044"},{"key":"bibr7-1753495X18784081","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2008.02427.x"},{"key":"bibr8-1753495X18784081","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02548.x"},{"key":"bibr9-1753495X18784081","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1408932"},{"key":"bibr10-1753495X18784081","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2017.02.367"},{"key":"bibr11-1753495X18784081","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gft012"},{"key":"bibr12-1753495X18784081","unstructured":"www.kidneyresearchuk.org\/health-information\/living-with-one-kidney (accessed 9 June 2018)"},{"key":"bibr13-1753495X18784081","volume-title":"Hypertension in pregnancy: diagnosis and management. 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