{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T22:41:48Z","timestamp":1787784108627,"version":"build-2784847793"},"reference-count":34,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2018,11,7]],"date-time":"2018-11-07T00:00:00Z","timestamp":1541548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Obstet Med"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> Insulin delivery options for pregnant women with type 1 diabetes mellitus are either continuous subcutaneous insulin infusion or multiple daily injections. The aim of this paper is to compare pregnancy outcomes in women with type 1 diabetes mellitus using continuous subcutaneous insulin infusion or multiple daily injections in pregnancy. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> Retrospective single-centre cohort study of 298 pregnancies booked between 2006 and 2016. Descriptive analysis was performed for HbA1c values. Logistic regression models were created to compare selected maternal and neonatal outcomes. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> Continuous subcutaneous insulin infusion was associated with increased risk of large-for-gestational age (aOR 2.00, 95% CI 1.20\u20133.34) and preterm neonates (aOR 1.80, 95% CI 1.04\u20133.03). Continuous subcutaneous insulin infusion had no association with increased risk of adverse pregnancy outcomes. No difference in HbA1c values existed between groups. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p> Using continuous subcutaneous insulin infusion for type 1 diabetes mellitus through pregnancy is associated with increased risk of large-for-gestational age and preterm neonates, without increased risk of associated adverse maternal or neonatal outcomes. <\/jats:p><\/jats:sec>","DOI":"10.1177\/1753495x18797769","type":"journal-article","created":{"date-parts":[[2018,11,7]],"date-time":"2018-11-07T11:10:49Z","timestamp":1541589049000},"page":"136-142","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Pregnancy outcomes among women with type 1 diabetes mellitus using continuous subcutaneous insulin infusion versus multiple daily injections: A retrospective cohort study"],"prefix":"10.1177","volume":"12","author":[{"given":"Benjamin RS","family":"Dixon","sequence":"first","affiliation":[{"name":"Department of Maternity Services & Pregnancy Research Centre, The Royal Women\u2019s Hospital, Parkville, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Nankervis","sequence":"additional","affiliation":[{"name":"Department of Maternity Services & Pregnancy Research Centre, The Royal Women\u2019s Hospital, Parkville, Australia"},{"name":"Department of Diabetes and Endocrinology, Royal Melbourne Hospital, Parkville, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie CN","family":"Hopkins","sequence":"additional","affiliation":[{"name":"Department of Maternity Services & Pregnancy Research Centre, The Royal Women\u2019s Hospital, Parkville, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J","family":"Cade","sequence":"additional","affiliation":[{"name":"Department of Maternity Services & Pregnancy Research Centre, The Royal Women\u2019s Hospital, Parkville, Australia"},{"name":"Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,11,7]]},"reference":[{"key":"bibr1-1753495X18797769","unstructured":"National Institute for Health and Care Excellence (2016) Diabetes in pregnancy (QS109). 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