{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:08:06Z","timestamp":1777381686875,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T00:00:00Z","timestamp":1573171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Obstet Med"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> Iron deficiency anaemia in pregnancy is common and is a major cause of maternal and neonatal morbidity worldwide. Serum ferritin is the current gold standard test for identifying iron depletion, with a cut-off value of 30\u2009\u00b5g\/L. Recent studies in low- and middle-income countries have identified mean cell haemoglobin concentration as a surrogate marker for the prediction of iron depletion. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> We studied values from 786 antenatal blood results from 2018 in Oxford, UK, and correlated the red cell indices with serum ferritin measurements. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> Haemoglobin, mean cell volume, mean cell haemoglobin and mean cell haemoglobin concentration have low specificity and sensitivity for the identification of iron depletion. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p> We found that haemoglobin, mean cell volume, mean cell haemoglobin and mean cell haemoglobin concentration do not have sufficient predictive value in this population to be used as a screening test for non-anaemic iron depletion. <\/jats:p><\/jats:sec>","DOI":"10.1177\/1753495x19878617","type":"journal-article","created":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T16:49:47Z","timestamp":1573231787000},"page":"23-25","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Utility of erythrocyte indices in identifying iron depletion in pregnancy"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9816-8589","authenticated-orcid":false,"given":"Sona M","family":"Vora","sequence":"first","affiliation":[{"name":"Department of Haematology, Oxford University Hospitals NHS Trust, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianfranco","family":"Messina","sequence":"additional","affiliation":[{"name":"University of Oxford, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sue","family":"Pavord","sequence":"additional","affiliation":[{"name":"Department of Haematology, Oxford University Hospitals NHS Trust, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,11,8]]},"reference":[{"key":"bibr1-1753495X19878617","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(18)30078-0"},{"key":"bibr2-1753495X19878617","volume-title":"Iron deficiency anaemia: assessment, prevention, and control \u2013 a guide for programme managers","author":"World Health Organization","year":"2001"},{"key":"bibr3-1753495X19878617","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2011.09012.x"},{"key":"bibr4-1753495X19878617","author":"WHO.","journal-title":"Vitam Miner Nutr Inf Syst"},{"key":"bibr5-1753495X19878617","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1993.tb03225.x"},{"key":"bibr6-1753495X19878617","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1998.01035.x"},{"key":"bibr7-1753495X19878617","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2018.11.009"},{"key":"bibr8-1753495X19878617","doi-asserted-by":"publisher","DOI":"10.1186\/s12878-018-0131-2"},{"key":"bibr9-1753495X19878617","doi-asserted-by":"publisher","DOI":"10.3329\/bmrcb.v37i3.9122"},{"key":"bibr10-1753495X19878617","doi-asserted-by":"crossref","unstructured":"Tiwari M, Kotwal J, Kotwal A, et al. \nCorrelation of haemoglobin and red cell indices with serum ferritin in Indian women in second and third trimester of pregnancy. 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