{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T01:09:33Z","timestamp":1789175373321,"version":"build-2803163510"},"reference-count":7,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T00:00:00Z","timestamp":1594684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Obstet Med"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p> Acute splenic sequestration crisis, characterized by abrupt fall in hemoglobin, splenomegaly, hypovolemia, and often thrombocytopenia, occurs infrequently in adults with sickle cell disease and extremely rarely during pregnancy. <\/jats:p><\/jats:sec><jats:sec><jats:title>Case<\/jats:title><jats:p> A 25-year-old woman with HbSC presented at 33 weeks\u2019 gestation with vaso-occlusive pain. Sudden worsening of abdominal pain and non-reassuring fetal surveillance on day 3 of admission led to emergent delivery. Acute splenic sequestration crisis was the diagnosis of exclusion based on clinical presentation and intra-operative hemoglobin of 37\u2009g\/L. Five- and 10-minute Apgar scores were 4. Neonatal brain magnetic resonance imaging revealed significant diffuse white matter abnormalities. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p> Acute splenic sequestration crisis in pregnancy must be considered in the differential diagnosis for this patient population as it can evolve rapidly and lead to maternal and fetal compromise. <\/jats:p><\/jats:sec>","DOI":"10.1177\/1753495x20936902","type":"journal-article","created":{"date-parts":[[2020,7,15]],"date-time":"2020-07-15T06:34:56Z","timestamp":1594794896000},"page":"113-115","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Adverse outcome of acute splenic sequestration crisis in pregnancy"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3466-7570","authenticated-orcid":false,"given":"Ann Kinga","family":"Malinowski","sequence":"first","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynaecology, Mount Sinai Hospital, Toronto, Canada"},{"name":"Department of Medicine, University of Toronto, Toronto, Canada"},{"name":"Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Parrish","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynaecology, Mount Sinai Hospital, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohan","family":"D\u2019Souza","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynaecology, Mount Sinai Hospital, Toronto, Canada"},{"name":"Department of Medicine, University of Toronto, Toronto, Canada"},{"name":"Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin HM","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Toronto, Toronto, Canada"},{"name":"Division of Haematology, Department of Medicine, University Health Network, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Ward","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Toronto, Toronto, Canada"},{"name":"Division of Haematology, Department of Medicine, University Health Network, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine","family":"Shehata","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Toronto, Toronto, Canada"},{"name":"Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Canada"},{"name":"Division of Haematology, Department of Medicine, Mount Sinai Hospital, Toronto, Canada"},{"name":"Division of Medical Oncology and Haematology, Department of Medicine, University Health Network, Toronto, Canada"},{"name":"Department of Laboratory Medicine and Pathobiology, Mount Sinai Hospital, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,7,14]]},"reference":[{"key":"bibr1-1753495X20936902","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12950"},{"key":"bibr2-1753495X20936902","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1002\/ajh.21550","volume":"85","author":"Ballas SK","year":"2010","journal-title":"Am J 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