{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T10:40:02Z","timestamp":1778236802040,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2020,12,8]],"date-time":"2020-12-08T00:00:00Z","timestamp":1607385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Obstet Med"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:p> Cirrhosis is a multisystemic condition in which pregnancy is uncommon; however, the combination may lead to a higher incidence of spontaneous fetal loss and complications such as progressive jaundice, ascites and variceal bleeding. Here we present a 21-year-old woman who presented at 14 weeks\u2019 gestation with new jaundice and a two-month history of melena consistent with pre-existing cirrhosis of unclear aetiology. She delivered a healthy male infant at 34\u2009weeks and five\u2009days of gestation vaginally with good haemostasis. In the literature, maternal mortality rates have been reported in up to 61% of these women, however, this risk is likely lower now with modern endoscopic therapies and improved access to blood products. There is limited information about labour and delivery in cirrhosis, although the best outcomes to date have been described in well-compensated women. <\/jats:p>","DOI":"10.1177\/1753495x20972828","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T18:22:53Z","timestamp":1607624573000},"page":"56-58","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Primary sclerosing cholangitis: A new case of cirrhosis in pregnancy"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8168-3947","authenticated-orcid":false,"given":"Vidya","family":"Sujana Kumar","sequence":"first","affiliation":[{"name":"Department of Medicine, Scarborough Health Network, Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karim","family":"Qumosani","sequence":"additional","affiliation":[{"name":"Department of Medicine, Schulich School of Medicine and Dentistry, Western University, Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taryn","family":"Taylor","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Schulich School of Medicine and Dentistry, Western University, Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongmei","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Medicine, Schulich School of Medicine and Dentistry, Western University, Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,12,8]]},"reference":[{"key":"bibr1-1753495X20972828","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60383-9"},{"key":"bibr2-1753495X20972828","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002055"},{"key":"bibr3-1753495X20972828","doi-asserted-by":"publisher","DOI":"10.1002\/lt.21572"},{"key":"bibr4-1753495X20972828","doi-asserted-by":"publisher","DOI":"10.1016\/j.cld.2018.12.013"},{"key":"bibr5-1753495X20972828","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2006.06.017"},{"key":"bibr6-1753495X20972828","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2015.11.030"},{"key":"bibr7-1753495X20972828","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/5819819"},{"key":"bibr8-1753495X20972828","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2011.03.036"},{"key":"bibr9-1753495X20972828","first-page":"356560","volume":"2013","author":"Kimmich N","year":"2013","journal-title":"Case Rep Obstet Gynecol"},{"key":"bibr10-1753495X20972828","volume":"21","author":"Robertson M","year":"2017","journal-title":"Ann Clin Case Rep"},{"key":"bibr11-1753495X20972828","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-015-1053-z"},{"key":"bibr12-1753495X20972828","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2009.02153.x"},{"key":"bibr13-1753495X20972828","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1704559"},{"key":"bibr14-1753495X20972828","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0676.1996.tb00754.x"},{"key":"bibr15-1753495X20972828","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2010.228924"},{"key":"bibr16-1753495X20972828","doi-asserted-by":"publisher","DOI":"10.4081\/cp.2011.e55"},{"key":"bibr17-1753495X20972828","doi-asserted-by":"publisher","DOI":"10.1016\/S2210-7401(12)70017-7"}],"container-title":["Obstetric Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1753495X20972828","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1753495X20972828","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1753495X20972828","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T10:03:41Z","timestamp":1740996221000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1753495X20972828"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,8]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["10.1177\/1753495X20972828"],"URL":"https:\/\/doi.org\/10.1177\/1753495x20972828","relation":{},"ISSN":["1753-495X","1753-4968"],"issn-type":[{"value":"1753-495X","type":"print"},{"value":"1753-4968","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,8]]}}}