{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T05:08:10Z","timestamp":1793336890312,"version":"4.5.0"},"reference-count":47,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2021,5,11]],"date-time":"2021-05-11T00:00:00Z","timestamp":1620691200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["R01HD 078515"],"award-info":[{"award-number":["R01HD 078515"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01HL130702"],"award-info":[{"award-number":["R01HL130702"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Brown Medical School Summer Research Assistantship"},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["P20 GM103652"],"award-info":[{"award-number":["P20 GM103652"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Obstet Med"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To examine whether change in neutrophil\u2013lymphocyte ratio, a marker of systemic inflammation, differs by childhood adversity and prenatal depression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Prenatal complete blood count data were used to calculate neutrophil\u2013lymphocyte ratio in first and third trimesters. The Adverse Childhood Experiences scale measured childhood adversity, and the Patient Health Questionnaire-9 measured depression. This is a secondary analysis of a study of predictors of risk for sleep-disordered breathing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Participants were 98 pregnant women, mean age 30 years ( SD\u2009=\u20095), mean body mass index of 35\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ( SD\u2009=\u20097), 61% identified as white, and 28% identified as Hispanic. Women who reported childhood sexual abuse history displayed greater increase in neutrophil\u2013lymphocyte ratio over pregnancy relative to women without childhood sexual abuse. Change in neutrophil\u2013lymphocyte ratio across pregnancy did not differ by prenatal depression.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Experiences of sexual abuse in childhood may impact markers of systemic inflammation in pregnancy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1753495x211011910","type":"journal-article","created":{"date-parts":[[2021,5,12]],"date-time":"2021-05-12T02:35:44Z","timestamp":1620786944000},"page":"25-30","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Childhood adversity, prenatal depression, and maternal inflammation across pregnancy"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8765-7846","authenticated-orcid":false,"given":"Margaret 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