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Critical illness and respiratory failure are relatively uncommon occurrences during pregnancy, and there are limited high-quality data to direct management. This paper reviews the current literature on COVID-19 management as it relates to pregnancy, and provides an overview of critical care support in these patients. COVID-19 drug therapy is similar to that used in the non-pregnant patient, including anti-inflammatory therapy with steroids and IL-6 inhibitors, although safety data are limited for antiviral drugs such as remdesivir and monoclonal antibodies. As both pregnancy and COVID-19 are thrombogenic, thromboprophylaxis is essential. Endotracheal intubation is a higher risk during pregnancy, but mechanical ventilation should follow usual principles. ICU management should be directed at optimizing maternal well-being, which in turn will benefit the fetus. <\/jats:p>","DOI":"10.1177\/1753495x211051246","type":"journal-article","created":{"date-parts":[[2021,11,2]],"date-time":"2021-11-02T08:39:41Z","timestamp":1635842381000},"page":"220-224","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["COVID-19 critical illness in pregnancy"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6930-0306","authenticated-orcid":false,"given":"Stephen E","family":"Lapinsky","sequence":"first","affiliation":[{"name":"Faculty of Medicine, University of Toronto, Canada"},{"name":"Intensive Care Unit, Mount Sinai Hospital, Canada"},{"name":"Interdepartmental Division of Critical Care Medicine, University of Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maha","family":"Al Mandhari","sequence":"additional","affiliation":[{"name":"Interdepartmental Division of Critical Care Medicine, University of Toronto, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,11,2]]},"reference":[{"key":"bibr1-1753495X211051246","unstructured":"Money D. 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