{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T06:05:36Z","timestamp":1741068336536,"version":"3.38.0"},"reference-count":13,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T00:00:00Z","timestamp":1671408000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Obstet Med"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:p> Maternal Graves\u2019 autoantibodies are well known to cause fetal and neonatal thyroid disturbances. Despite radioiodine therapy, Graves\u2019 autoantibodies are known to persist, which can cross the placenta and cause hyperthyroidism in the fetus. We present the case of a 26-year-old woman in her first pregnancy, clinically and biochemically euthyroid with history of treated Graves\u2019 disease, where the fetus showed signs of hyperthyroidism on antenatal scans. This was confirmed by amniotic fluid testing as fetal blood sampling was not feasible and successfully treated with maternal carbimazole whilst continuing thyroxine for the mother (block-replacement). We discuss the challenges in the diagnosis of fetal hyperthyroidism and treatment whilst maternal thyroid status is maintained on thyroxine. <\/jats:p>","DOI":"10.1177\/1753495x221146340","type":"journal-article","created":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T07:26:26Z","timestamp":1671521186000},"page":"108-111","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Management of fetal hyperthyroidism caused by persistent autoimmune antibodies in a case of previously treated maternal Graves\u2019 disease"],"prefix":"10.1177","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8587-8581","authenticated-orcid":false,"given":"Susmita Reddy","family":"Karri","sequence":"first","affiliation":[{"name":"Department of Endocrinology, Townsville University Hospital, Douglas, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priya Susan","family":"Roy","sequence":"additional","affiliation":[{"name":"Genetic Pathology, Pathology Queensland, Brisbane, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nirjhar","family":"Nandi","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Cairns Hospital, Cairns, Australia"},{"name":"James Cook University, Cairns, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasant","family":"Shenoy","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Townsville University Hospital, Douglas, Australia"},{"name":"James Cook University, Townsville, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Watson","sequence":"additional","affiliation":[{"name":"James Cook University, Townsville, Australia"},{"name":"Department of Maternal and Fetal Medicine, Townsville University Hospital, Douglas, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,12,19]]},"reference":[{"key":"bibr1-1753495X221146340","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2016.0457"},{"key":"bibr2-1753495X221146340","doi-asserted-by":"publisher","DOI":"10.1159\/000453065"},{"key":"bibr3-1753495X221146340","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2017.00137"},{"key":"bibr4-1753495X221146340","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-1878"},{"key":"bibr5-1753495X221146340","volume":"2015","author":"Correia MF","year":"2015","journal-title":"BMJ Case Rep"},{"key":"bibr6-1753495X221146340","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-07-0450"},{"key":"bibr7-1753495X221146340","doi-asserted-by":"publisher","DOI":"10.1007\/BF03346581"},{"key":"bibr8-1753495X221146340","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2016.0457"},{"key":"bibr9-1753495X221146340","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-2555"},{"key":"bibr10-1753495X221146340","doi-asserted-by":"publisher","DOI":"10.1258\/om.2011.110074"},{"key":"bibr11-1753495X221146340","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-030522"},{"key":"bibr12-1753495X221146340","doi-asserted-by":"publisher","DOI":"10.1186\/s40842-018-0054-7"},{"key":"bibr13-1753495X221146340","first-page":"3099","volume":"82","author":"Mortimer RH","year":"1997","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Obstetric Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1753495X221146340","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1753495X221146340","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1753495X221146340","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T00:50:58Z","timestamp":1741049458000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1753495X221146340"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,19]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1177\/1753495X221146340"],"URL":"https:\/\/doi.org\/10.1177\/1753495x221146340","relation":{},"ISSN":["1753-495X","1753-4968"],"issn-type":[{"type":"print","value":"1753-495X"},{"type":"electronic","value":"1753-4968"}],"subject":[],"published":{"date-parts":[[2022,12,19]]}}}