{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T01:18:16Z","timestamp":1784942296171,"version":"3.55.0"},"reference-count":13,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T00:00:00Z","timestamp":1716163200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Obstet Med"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:p>\n                    Primary membranous nephropathy remains a rare but challenging condition to manage in pregnancy. We present a case of an unplanned pregnancy in a 35-year-old woman with PLA\n                    <jats:sub>2<\/jats:sub>\n                    R-antibody positive membranous nephropathy, who had demonstrated serological response to rituximab given three months prior to pregnancy (PLA\n                    <jats:sub>2<\/jats:sub>\n                    R 115\u2009IUmL reducing to 2\u2009IU\/mL, normal &lt;13.9\u2009IU\/mL)). Throughout pregnancy, serial measurements of proteinuria and PLA\n                    <jats:sub>2<\/jats:sub>\n                    R-antibodies were used to understand disease activity and inform the decision to escalate treatment. Delivery of a healthy male infant occurred at 34 weeks, due to threatened pre-eclampsia and reduced fetal growth. There was evidence of trans-placental transfer of antibodies (15.2\u2009IU\/mL \u2013 normal &lt;13.9\u2009IU\/mL) but no associated nephrotic syndrome in the infant. This case highlights the potential of PLA\n                    <jats:sub>2<\/jats:sub>\n                    R antibody as a diagnostic and monitoring tool during pregnancy, and adds to a small body of literature around the consequences of fetal\u2013maternal transfer of the PLA\n                    <jats:sub>2<\/jats:sub>\n                    R antibody.\n                  <\/jats:p>","DOI":"10.1177\/1753495x241255555","type":"journal-article","created":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T06:46:26Z","timestamp":1716187586000},"page":"70-72","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The utility of phospholipase A\n                    <sub>2<\/sub>\n                    receptor antibody in pregnancy: A case report"],"prefix":"10.1177","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4539-0957","authenticated-orcid":false,"given":"Alessandra","family":"Orsillo","sequence":"first","affiliation":[{"name":"Central Northern Adelaide Renal and Transplantation Service, Adelaide, South Australia"},{"name":"The University of Adelaide, Adelaide, South Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishanta","family":"Tangirala","sequence":"additional","affiliation":[{"name":"Central Northern Adelaide Renal and Transplantation Service, Adelaide, South Australia"},{"name":"The University of Adelaide, Adelaide, South Australia"},{"name":"Women's and Children's Hospital Foundation, North Adelaide, South Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shilpanjali","family":"Jesudason","sequence":"additional","affiliation":[{"name":"Central Northern Adelaide Renal and Transplantation Service, Adelaide, South Australia"},{"name":"The University of Adelaide, Adelaide, South Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,5,20]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfq665"},{"key":"e_1_3_2_3_2","volume-title":"Comprehensive clinical nephrology","author":"Floege J","year":"2010","unstructured":"Floege J, Johnson RJ, Feehally J (eds). Front matter. In: Comprehensive clinical nephrology. 4th ed. Philadelphia: Mosby, 2010 [cited 2023 Aug 3], pp.i\u2013iii. https:\/\/www.sciencedirect.com\/science\/article\/pii\/B9780323058766001118"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1159\/000505175"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0810457"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2015.10.031"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13730-018-0304-7"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/985646"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1530\/ror.0.0040081"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2019.11.011"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-07-295444"},{"key":"e_1_3_2_12_2","article-title":"Pregnancy outcomes following maternal treatment with rituximab prior to or during pregnancy: a case series","volume":"5","author":"Perrotta K","year":"2021","unstructured":"Perrotta K, Kiernan E, Bandoli G, et al. Pregnancy outcomes following maternal treatment with rituximab prior to or during pregnancy: a case series. Rheumatol Adv Pract 2021; 5: rkaa074.","journal-title":"Rheumatol Adv Pract"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000000734"},{"key":"e_1_3_2_14_2","unstructured":"Australian public assessment report for Rituximab. 2021."}],"container-title":["Obstetric Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1753495X241255555","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1753495X241255555","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1753495X241255555","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T14:17:42Z","timestamp":1775571462000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1753495X241255555"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,20]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1177\/1753495X241255555"],"URL":"https:\/\/doi.org\/10.1177\/1753495x241255555","relation":{},"ISSN":["1753-495X","1753-4968"],"issn-type":[{"value":"1753-495X","type":"print"},{"value":"1753-4968","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,20]]}}}