{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:32:27Z","timestamp":1790785947617,"version":"4.1.0"},"reference-count":39,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,6,2]],"date-time":"2024-06-02T00:00:00Z","timestamp":1717286400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Obstet Med"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:p>Microvascular, placental, haematological and lipid studies suggest striking similarities between preeclampsia\/eclampsia and atherosclerosis.<\/jats:p>\n          <jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>To determine the lipid profile and atherogenic indices in preeclamptic\/eclamptic patients and compare with normal pregnant women.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methodology<\/jats:title>\n            <jats:p>Comparative cross-sectional study conducted in North Central Nigeria. The study population was preeclamptic\/eclamptic patients and normal pregnant women. A total of 192 women, comprising 96 pregnant women with preeclampsia\/eclampsia and an equal number of normotensive controls were recruited consecutively by purposive sampling. Lipid profiles were estimated and atherogenic indices were calculated.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Result<\/jats:title>\n            <jats:p>\n              Coronary heart disease risk ratio (CRR) and atherogenic index of plasma (AIP) showed significantly increased atherogenic potentials in subjects compared to controls. Mean\u2009\u00b1\u2009SD CRR of subjects was 0.28\u2009\u00b1\u20090.17, Mean\u2009\u00b1\u2009SD CRR of controls was 0.44\u2009\u00b1\u20090.24 (\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.001); Mean\u2009\u00b1\u2009SD AIP of subjects was 0.32\u2009\u00b1\u20090.42 and mean\u2009\u00b1\u2009SD AIP of controls was 0.16\u2009\u00b1\u20090.26 (\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.003).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Atherogenic indices show increased atherogenic potentials in preeclamptic\/eclamptics.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1177\/1753495x241258676","type":"journal-article","created":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T02:59:54Z","timestamp":1717383594000},"page":"87-93","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Atherogenic indices in preeclamptic and eclamptic patients in North-Central Nigeria"],"prefix":"10.1177","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2514-5284","authenticated-orcid":false,"given":"Zainab Ajoke","family":"Abdulkadir","sequence":"first","affiliation":[{"name":"General Hospital Ilorin, Ilorin, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munirdeen Aderemi","family":"Ijaiya","sequence":"additional","affiliation":[{"name":"University of Ilorin Teaching Hospital, Ilorin, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idowu O","family":"Adebara","sequence":"additional","affiliation":[{"name":"Federal Teaching Hospital Ido-Ekiti, Ado Ekiti, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,6,2]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"234","volume-title":"Textbook of obstetrics","author":"Dutta DC","year":"2011","unstructured":"Dutta DC. Hypertensive disorders in pregnancy. In: Konar HL (eds) Textbook of obstetrics. 7th ed. Kolkata: New Central Book Agency, 2011, pp. 234\u2013255.","edition":"7"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/9781119979449.ch11"},{"key":"e_1_3_3_4_2","first-page":"706","volume-title":"Williams obstetrics","author":"Cunningham FG","year":"2010","unstructured":"Pregnancy hypertension. In: Cunningham FG, Leveno KJ, Bloom SL, Hauth JC, Rouse DJ, Sprong CV (eds) Williams obstetrics. 23rd ed. New York: McGraw-Hill, 2010, pp. 706\u2013756.","edition":"23"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40885-021-00178-y"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.118.313276"},{"key":"e_1_3_3_7_2","first-page":"97","article-title":"Prevalence, risk factors, maternal and perinatal outcome of patients with eclampsia in university of Maiduguri teaching hospital, Maiduguri, Nigeria: a 15-year retrospective review","volume":"40","author":"Geidam AD","unstructured":"Geidam AD, Atterwahmie A, Usman A, et al. Prevalence, risk factors, maternal and perinatal outcome of patients with eclampsia in university of Maiduguri teaching hospital, Maiduguri, Nigeria: a 15-year retrospective review. West Afr J Med 2023 Jan 30; 40: 97\u2013103.","journal-title":"West Afr J Med"},{"key":"e_1_3_3_8_2","first-page":"4382","article-title":"Maternal and perinatal outcome in severe preeclampsia and eclampsia at the rivers state university teaching hospital, Nigeria","volume":"9","author":"Awoyesuku PA","unstructured":"Awoyesuku PA, John DH, Lebara LB. Maternal and perinatal outcome in severe preeclampsia and eclampsia at the rivers state university teaching hospital, Nigeria. Int J Reprod Contracept Obstet Gynecol 2020 Nov; 9: 4382\u20134388. www.ijrcog.org","journal-title":"Int J Reprod Contracept Obstet Gynecol"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.4103\/TJOG.TJOG_45_19"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.4314\/ahs.v18i3.16"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2022.10.007"},{"key":"e_1_3_3_12_2","first-page":"47","article-title":"Perinatal outcomes of severe preeclampsia \/eclampsia and associated factors among mothers admitted in Amhara Region referral hospitals, North West Ethiopia","volume":"12","author":"Melese MF","year":"2018","unstructured":"Melese MF, Badi MB, Aynalem GL. Perinatal outcomes of severe preeclampsia \/eclampsia and associated factors among mothers admitted in Amhara Region referral hospitals, North West Ethiopia. BMC Res Notes 2018; 12: 47.","journal-title":"BMC Res Notes"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.4103\/0300-1652.140377"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.4103\/2278-0521.142317"},{"key":"e_1_3_3_15_2","article-title":"Report of the National High Blood Pressure Education Program Working Group on high blood pressure in pregnancy","volume":"183","author":"National High Blood Pressure Education Program.","year":"2000","unstructured":"National High Blood Pressure Education Program. Report of the National High Blood Pressure Education Program Working Group on high blood pressure in pregnancy. Am J Obstet Gynecol 2000; 183: S1\u2013S22.","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_3_3_16_2","first-page":"1391","article-title":"New AHA recommendations for blood pressure measurement","volume":"72","author":"Smith L","year":"2005","unstructured":"Smith L. New AHA recommendations for blood pressure measurement. Am Fam Physician 2005; 72: 1391\u20131398.","journal-title":"Am Fam Physician"},{"key":"e_1_3_3_17_2","article-title":"Preeclampsia and future cardiovascular health: a systematic review and meta-analysis","volume":"10","author":"Wu P","unstructured":"Wu P, Haththotuwa R, Kwok CS, et al. Preeclampsia and future cardiovascular health: a systematic review and meta-analysis. Circ Cardiovasc Qual Outcomes Feb 2017; 10: e003497.","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41371-023-00812-2"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.5077"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwu145"},{"key":"e_1_3_3_21_2","article-title":"Maternal lipid profile and risk of pre-eclampsia in African pregnant women: a systematic review and meta-analysis","volume":"15","author":"Tesfa E","unstructured":"Tesfa E, Nibret E, Munshea A. Maternal lipid profile and risk of pre-eclampsia in African pregnant women: a systematic review and meta-analysis. PLoS One 2020 Dec 23; 15: e0243538.","journal-title":"PLoS One"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.18203\/2320-1770.ijrcog20191969"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.3109\/10641955.2015.1115060"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-107078"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/hsr2.806"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.15406\/ogij.2019.10.00439"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mvr.2021.104216"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.114.03575"},{"key":"e_1_3_3_29_2","first-page":"1","article-title":"Endothelial dysfunction in hypertension: current concepts and clinical implications","volume":"8","author":"Giovanna G","year":"2022","unstructured":"Giovanna G, Massimo V, Carmine S. Endothelial dysfunction in hypertension: current concepts and clinical implications. Front. Med 2022; 8: 1\u20138.","journal-title":"Front. Med"},{"key":"e_1_3_3_30_2","first-page":"3092","article-title":"The relationship between oxidative stress and atherogenic index (A.I.) in preeclampsia","volume":"2","author":"Bharadwaj R","year":"2014","unstructured":"Bharadwaj R, Mathur K, Sharma D, et al. The relationship between oxidative stress and atherogenic index (A.I.) in preeclampsia. Sch J App Med Sci 2014; 2: 3092\u20133096.","journal-title":"Sch J App Med Sci"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.4236\/ijcm.2013.45042"},{"key":"e_1_3_3_32_2","first-page":"240","article-title":"Atherogenic index of plasma (AIP): a marker of cardiovascular disease","volume":"29","author":"Niroumand S","year":"2015","unstructured":"Niroumand S, Khajedaluee M, Khadem-Rezaiyan M, et al. Atherogenic index of plasma (AIP): a marker of cardiovascular disease. Med J Islam Repub Iran 2015; 29: 240.","journal-title":"Med J Islam Repub Iran"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.21303\/2504-5679.2016.00230"},{"key":"e_1_3_3_34_2","first-page":"6","article-title":"Trends in TC\/HDL and LDL\/HDL ratios across the age span: data from the 2007-2018 national health and nutrition examination survey (NHANES)","volume":"9","author":"Wang I","year":"2021","unstructured":"Wang I. Trends in TC\/HDL and LDL\/HDL ratios across the age span: data from the 2007-2018 national health and nutrition examination survey (NHANES). Asian J Compl Altern Med 2021; 9: 6\u201315.","journal-title":"Asian J Compl Altern Med"},{"key":"e_1_3_3_35_2","first-page":"8","article-title":"Scientific research sample size determination","volume":"11","author":"Muyembe Asenahabi B","year":"2023","unstructured":"Muyembe Asenahabi B, Anselemo Ikoha P. Scientific research sample size determination. Int J Sci Technol 2023; 11: 8\u201312.","journal-title":"Int J Sci Technol"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw152"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.08.006"},{"key":"e_1_3_3_38_2","first-page":"638","article-title":"Maternal serum lipids in women with pre-eclampsia","volume":"4","author":"Siddiqui I","year":"2014","unstructured":"Siddiqui I. Maternal serum lipids in women with pre-eclampsia. AMHSR 2014; 4: 638\u2013641.","journal-title":"AMHSR"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.18410\/jebmh\/2016\/516"},{"key":"e_1_3_3_40_2","article-title":"A study on atherogenic indices of pregnancy induced hypertension patients as compared to normal pregnant women","volume":"9","author":"Singh M","year":"2015","unstructured":"Singh M, Pathak MS, Paul A. A study on atherogenic indices of pregnancy induced hypertension patients as compared to normal pregnant women. JCDR 2015; 9: BC05\u2013BC08.","journal-title":"JCDR"}],"container-title":["Obstetric Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1753495X241258676","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1753495X241258676","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1753495X241258676","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T11:17:50Z","timestamp":1747739870000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1753495X241258676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,2]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1177\/1753495X241258676"],"URL":"https:\/\/doi.org\/10.1177\/1753495x241258676","relation":{},"ISSN":["1753-495X","1753-4968"],"issn-type":[{"value":"1753-495X","type":"print"},{"value":"1753-4968","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,2]]}}}