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A case of a rapid fall in insulin requirements in a woman with type 2 diabetes mellitus, obesity, hypertension and chronic kidney disease at 23 weeks\u2019 gestation with high titres of insulin antibodies is presented. The possibility of exogenous insulin autoimmune syndrome as a cause for hypoglycaemia and reduction in insulin requirements is discussed.<\/jats:p>","DOI":"10.1177\/1753495x261418194","type":"journal-article","created":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T14:22:36Z","timestamp":1770042156000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Reduction in insulin requirements in second trimester in a woman with type 2 diabetes mellitus associated with anti-insulin antibodies: A case of exogenous insulin autoimmune syndrome?"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9887-714X","authenticated-orcid":false,"given":"Adam","family":"Morton","sequence":"first","affiliation":[{"name":"Mater Hospital Brisbane"},{"name":"University of Queensland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishwas","family":"Raghunath","sequence":"additional","affiliation":[{"name":"Mater Hospital Brisbane"},{"name":"Ipswich Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinwen","family":"He","sequence":"additional","affiliation":[{"name":"Mater Hospital Brisbane"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,2,2]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"1","article-title":"Falling insulin requirements in women with pregestational diabetes","volume":"70","author":"Carmi AWY","year":"2020","unstructured":"Carmi AWY, Tali S, et al. 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