{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T11:06:25Z","timestamp":1779188785675,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T00:00:00Z","timestamp":1772928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Obstet Med"],"abstract":"<jats:p>\n                    Haemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening hyperinflammatory syndrome. It is uncommon in the postpartum period and frequently under-recognised. Described here is a 31-year-old woman who developed HLH shortly after an uncomplicated emergency caesarean section. Initial postpartum pyrexia was attributed to\n                    <jats:italic toggle=\"yes\">Staphylococcus aureus<\/jats:italic>\n                    bacteraemia and treated with intravenous antibiotics. Extensive investigations failed to identify an infectious source. An H-score of 216 indicated a high likelihood of HLH, and treatment with intravenous methylprednisolone followed by anakinra resulted in clinical stabilisation and full recovery. This case highlights HLH as an important differential diagnosis in postpartum patients presenting with unexplained fever and haematological abnormalities. Early recognition and prompt initiation of immunosuppressive therapy are critical to improving outcomes in this potentially fatal but treatable condition.\n                  <\/jats:p>","DOI":"10.1177\/1753495x261425028","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T11:04:49Z","timestamp":1773227089000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Post-partum haemophagocytic lymphohistiocytosis triggered by\n                    <i>Staphylococcus aureus<\/i>\n                    bacteraemia or teicoplanin therapy"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-7169-4483","authenticated-orcid":false,"given":"Hannah","family":"Cooke","sequence":"first","affiliation":[{"name":"Great Western Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hala","family":"El-Masri","sequence":"additional","affiliation":[{"name":"Great Western Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabella","family":"Laws","sequence":"additional","affiliation":[{"name":"King\u2019s College Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kriti","family":"Sharma","sequence":"additional","affiliation":[{"name":"Great Western Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khin","family":"Yein","sequence":"additional","affiliation":[{"name":"Great Western Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosemary","family":"Waller","sequence":"additional","affiliation":[{"name":"Great Western Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,3,8]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2665-9913(23)00273-4"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.70013"},{"key":"e_1_3_2_4_2","article-title":"OA10 post-partum haemophagocytic lymphohistiocytosis","volume":"8","author":"Goulden B","year":"2024","unstructured":"Goulden B, Giles I, Wiles K, et al. OA10 post-partum haemophagocytic lymphohistiocytosis. Rheumatol Adv Pract 2024; 8: rkae117.010.","journal-title":"Rheumatol Adv Pract"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.575197"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/1753495X251356108"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2025.102763"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.38690"},{"key":"e_1_3_2_9_2","unstructured":"Getting\u202fIt\u202fRight\u202fFirst\u202fTime (GIRFT). Haemophagocytic lymphohistiocytosis (HLH): Guidance on the diagnosis treatment management and governance. 2024 https:\/\/gettingitrightfirsttime.co.uk\/wp-content\/uploads\/2025\/06\/HLH-Guide-final-version-v1.3-June-2025.pdf"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.614704"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.7070"}],"container-title":["Obstetric Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1753495X261425028","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1753495X261425028","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1753495X261425028","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T10:11:10Z","timestamp":1779185470000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1753495X261425028"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,8]]},"references-count":10,"alternative-id":["10.1177\/1753495X261425028"],"URL":"https:\/\/doi.org\/10.1177\/1753495x261425028","relation":{},"ISSN":["1753-495X","1753-4968"],"issn-type":[{"value":"1753-495X","type":"print"},{"value":"1753-4968","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,8]]},"article-number":"1753495X261425028"}}