{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T14:14:24Z","timestamp":1778076864706,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Obstet Med"],"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To determine the impact of tighter glycaemic targets for gestational diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective data analysis before and after introducing tighter glucose targets.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In 2265 pregnancies there was no change in large-for-gestational age babies (Odds ratio (OR) 1.1; 95% Confidence interval (CI) 0.8\u20131.6) and macrosomia (OR 1.0; 95% CI 0.6\u20131.7) following tighter glucose targets. Gestational hypertension (OR 0.4; 95% CI 0.2\u20130.7), spontaneous vaginal birth (OR 0.6; 95% CI 0.4\u20130.9) reduced and pharmacological treatment increased (OR 2.2; 95% CI 1.7\u20132.8).<\/jats:p>\n                    <jats:p>Composite adverse neonatal outcome (perinatal death, shoulder dystocia, fracture, nerve palsy) (OR 0.6; CI 0.02\u201314.2 p\u2009=\u20090.76)), Apgar&lt;7 at 5\u2005min, neonatal hypoglycaemia, respiratory distress syndrome or neonatal unit admission did not change but neonatal jaundice was reduced (OR 0.4; 95% CI 0.2\u20130.8).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Tighter glycaemic targets had no impact on large-for-gestational age babies or composite adverse neonatal outcomes. There was reduced spontaneous vaginal birth, gestational hypertension, neonatal jaundice and increased pharmacological treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1753495x261445509","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T14:52:07Z","timestamp":1777906327000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of tighter glycaemic targets on pregnancy outcomes in a multi-ethnic cohort with gestational diabetes: A retrospective, single centre observational study"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7303-199X","authenticated-orcid":false,"given":"Mohammed SB","family":"Huda","sequence":"first","affiliation":[{"name":"Royal London Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niki","family":"Margari","sequence":"additional","affiliation":[{"name":"Royal London Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7459-0467","authenticated-orcid":false,"given":"Nafisa","family":"Islam","sequence":"additional","affiliation":[{"name":"Royal London Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah","family":"Jaumdally","sequence":"additional","affiliation":[{"name":"Royal London Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0617-8144","authenticated-orcid":false,"given":"Kate","family":"Wiles","sequence":"additional","affiliation":[{"name":"Royal London Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rehan","family":"Khan","sequence":"additional","affiliation":[{"name":"Royal London Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Jacob","sequence":"additional","affiliation":[{"name":"Royal London Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Greco","sequence":"additional","affiliation":[{"name":"Queen Mary University of London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stamatina","family":"Iliodromiti","sequence":"additional","affiliation":[{"name":"Queen Mary University of London"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita","family":"Sanghi","sequence":"additional","affiliation":[{"name":"Royal London Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shakila","family":"Thangaratinam","sequence":"additional","affiliation":[{"name":"Queen Mary University of London"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO;2-S"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa042973"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0902430"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-2461"},{"key":"e_1_3_3_6_2","article-title":"Different intensities of glycaemic control for women with gestational diabetes mellitus","volume":"4","author":"Martis R","year":"2016","unstructured":"Martis R, Brown J, Alsweiler J, et al. 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