{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T21:29:33Z","timestamp":1769549373461,"version":"3.49.0"},"reference-count":50,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Cardiovascular Disease"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Severe burn injuries result in a massive systemic inflammatory and hypermetabolic response, often disrupting multiple organ systems, including the cardiovascular system. Cardiac troponins are frequently elevated in burn patients, but the interpretation of these elevations is hardly straightforward. Sometimes, elevated troponin means type 1 myocardial infarction (MI) due to an acute coronary event, but it might also reflect type 2 MI due to an imbalance between body oxygen demand and supply, or even non-ischemic myocardial injury from things like overwhelming inflammation, sepsis, or direct thermal effects on the heart itself. This narrative review explores the prevalence, underlying pathophysiological mechanisms, diagnostic challenges, and prognostic implications of troponin elevation in burn patients. We discussed the limitations of applying conventional MI diagnostic criteria in this unique population. The role of electrocardiographic and echocardiographic assessment, as well as the potential utility of high-sensitivity troponin assays, is also discussed. Understanding of how burn pathophysiology relates to myocardial injury is essential for accurate diagnosis, improved management, and better outcomes in this highly vulnerable group of patients.<\/jats:p>","DOI":"10.1177\/17539447251414564","type":"journal-article","created":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T07:26:17Z","timestamp":1769325977000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Troponins and echocardiography: role in detecting myocardial injury in burn patients"],"prefix":"10.1177","volume":"20","author":[{"given":"Mohammed","family":"AbuBaha","sequence":"first","affiliation":[{"name":"Department of Medicine, An-Najah National University, Nablus, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0866-7787","authenticated-orcid":false,"given":"Samia","family":"Aldwaik","sequence":"additional","affiliation":[{"name":"Department of Medicine, An-Najah National University, Nablus P400, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5122-8200","authenticated-orcid":false,"given":"Ameer","family":"Awashra","sequence":"additional","affiliation":[{"name":"Department of Medicine, An-Najah National University, Nablus, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fathi","family":"Milhem","sequence":"additional","affiliation":[{"name":"Department of Medicine, An-Najah National University, Nablus, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-7767-6573","authenticated-orcid":false,"given":"Anwar","family":"Zahran","sequence":"additional","affiliation":[{"name":"Department of Medicine, An-Najah National University, Nablus, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Husam","family":"Hamshary","sequence":"additional","affiliation":[{"name":"Department of Medicine, An-Najah National University, Nablus, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasan","family":"Fuqha","sequence":"additional","affiliation":[{"name":"Department of Medicine, An-Najah National University, Nablus, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Bdair","sequence":"additional","affiliation":[{"name":"Department of Medicine, An-Najah National University, Nablus, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bara","family":"Abubaha","sequence":"additional","affiliation":[{"name":"Department of Medicine, An-Najah National University, Nablus, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Saife","sequence":"additional","affiliation":[{"name":"Department of Medicine, An-Najah National University, Nablus, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdalhakim","family":"Shubietah","sequence":"additional","affiliation":[{"name":"Department of Medicine, An-Najah National University, Nablus, Palestine"},{"name":"Department of Internal Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,1,24]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/jbcr\/irae049"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/BCR.0000000000000355"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0000000000001465"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1995.tb14901.x"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1998.274.3.R577"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0305-4179(01)00051-1"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2007.11.013"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.shk.0000217814.93"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/BCR.0b013e3182685e11"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics14050503"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/jbcr\/irae086"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-018-0515-7"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.08.750"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0b013e31824caa72"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13144037"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-47661-4.00008-3"},{"key":"e_1_3_4_18_2","article-title":"Vascular response to burn shock","volume":"24","author":"Milner SM.","year":"2024","unstructured":"Milner SM. 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