{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T14:19:25Z","timestamp":1780323565056,"version":"3.54.1"},"reference-count":11,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Henan Medical Science and Technology Project","award":["LHGJ20230569"],"award-info":[{"award-number":["LHGJ20230569"]}]},{"name":"Scientific and Technological Projects of Henan province","award":["242102310163"],"award-info":[{"award-number":["242102310163"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Cardiovascular Disease"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:p>This case report describes a rare case of a giant right atrial aneurysm (RAA) in a 7-month-old male infant admitted to Children\u2019s Hospital Affiliated to Zhengzhou University in July 2025. A RAA was detected during a physical examination at 2\u2009months of age with no clinical symptoms present. Follow-up reexamination at 7\u2009months of age revealed progressive enlargement of the RAA, and the infant thus underwent aneurysm resection plus atrial septal defect repair under cardiopulmonary bypass. Postoperative histopathological examination confirmed the diagnosis of RAA. On the second postoperative day, the infant developed neurological complications including lethargy, skew deviation, mild hemiplegia, and focal epilepsy. The hospital immediately implemented a multimodal intervention strategy involving mannitol for dehydration, glucocorticoids for anti-inflammation, antiepileptic medication, and strict fluid management. The infant achieved near-complete recovery of neurological function at discharge on the 21st postoperative day, with significant improvement in brain abnormalities on follow-up at 1\u2009month postoperatively. This case highlights cytotoxic cerebral edema, a rare postoperative neurological complication following RAA resection in children, and emphasizes the importance of early identification and multimodal treatment for such complications, providing valuable clinical evidence for the perioperative management of pediatric cardiac surgery.<\/jats:p>","DOI":"10.1177\/17539447261453502","type":"journal-article","created":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T14:38:22Z","timestamp":1780151902000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Postoperative cytotoxic cerebral edema following surgical resection of a giant right atrial aneurysm in an infant: a rare case report"],"prefix":"10.1177","volume":"20","author":[{"given":"Hui","family":"Yan","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery, Children\u2019s Hospital Affiliated to Zhengzhou University, Henan Children\u2019s Hospital, Zhengzhou Children\u2019s Hospital, Zhengzhou, China"},{"name":"Henan Provincial Clinical Research Center for Pediatric Diseases, Henan Key Laboratory of Pediatric Genetics and Metabolic Diseases, Children\u2019s Hospital Affiliated to Zhengzhou University, Henan Children\u2019s Hospital, Zhengzhou Children\u2019s Hospital, Zhengzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Children\u2019s Hospital Affiliated to Zhengzhou University, Henan Children\u2019s Hospital, Zhengzhou Children\u2019s Hospital, Zhengzhou, China"},{"name":"Henan Provincial Clinical Research Center for Pediatric Diseases, Henan Key Laboratory of Pediatric Genetics and Metabolic Diseases, Children\u2019s Hospital Affiliated to Zhengzhou University, Henan Children\u2019s Hospital, Zhengzhou Children\u2019s Hospital, Zhengzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaiyuan","family":"Li","sequence":"additional","affiliation":[{"name":"Nanchang University Queen Mary School, Nanchang University, Nanchang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruiling","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Children\u2019s Hospital Affiliated to Zhengzhou University, Henan Children\u2019s Hospital, Zhengzhou Children\u2019s Hospital, Zhengzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Zhai","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Children\u2019s Hospital Affiliated to Zhengzhou University, Henan Children\u2019s Hospital, Zhengzhou Children\u2019s Hospital, Zhengzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7287-3702","authenticated-orcid":false,"given":"Zhenliang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Children\u2019s Hospital Affiliated to Zhengzhou University, Henan Children\u2019s Hospital, Zhengzhou Children\u2019s Hospital, No. 33, Longhu Outer Ring Road East, Zhengdong New District, Zhengzhou 450018, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,30]]},"reference":[{"key":"e_1_3_4_2_2","article-title":"Prenatal diagnosis of a right atrial appendage aneurysm: case report and review of the literature","volume":"14","author":"Miranda J","year":"2024","unstructured":"Miranda J, Villalobo DM, Alfieri N, et al. Prenatal diagnosis of a right atrial appendage aneurysm: case report and review of the literature. 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Mean arterial pressure difference before and during cardiopulmonary bypass: what should be the ideal mean perfusion pressure? Cir Cir 2025; 93: 425\u2013433.","journal-title":"Cir Cir"}],"container-title":["Therapeutic Advances in Cardiovascular Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17539447261453502","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/17539447261453502","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17539447261453502","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T13:17:27Z","timestamp":1780319847000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/17539447261453502"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":11,"alternative-id":["10.1177\/17539447261453502"],"URL":"https:\/\/doi.org\/10.1177\/17539447261453502","relation":{},"ISSN":["1753-9447","1753-9455"],"issn-type":[{"value":"1753-9447","type":"print"},{"value":"1753-9455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]},"article-number":"17539447261453502"}}