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Lifestyle, including dietary habits and physical activity, is a modifiable risk factor and thus represents the main target for the prevention and treatment of NAFLD. In this review, we summarize the evidence regarding nutritional aspects (i.e. total energy intake, saturated fat and carbohydrates intake, certain foods or drinks and dietary patterns as a whole) in the treatment of NAFLD. In addition, we analyze the evidence concerning the independent effect of physical activity, including aerobic and resistance training, in the treatment of NAFLD. A therapeutic algorithm according to results from intervention trials is also provided for clinicians and other healthcare professionals involved in the management of NAFLD. <\/jats:p>","DOI":"10.1177\/1756283x16638830","type":"journal-article","created":{"date-parts":[[2016,3,18]],"date-time":"2016-03-18T01:59:35Z","timestamp":1458266375000},"page":"392-407","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":120,"title":["Lifestyle changes for the treatment of nonalcoholic fatty liver disease: a review of observational studies and intervention trials"],"prefix":"10.1177","volume":"9","author":[{"given":"Shira","family":"Zelber-Sagi","sequence":"first","affiliation":[{"name":"School of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa"},{"name":"Department of Gastroenterology, Tel-Aviv Sourasky Medical Center, 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