{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:29:51Z","timestamp":1790616591065,"version":"4.1.0"},"reference-count":189,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therap Adv Gastroenterol"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec><jats:title>Background:<\/jats:title><jats:p> Liver cirrhosis is a major global health burden worldwide due to its high risk of morbidity and mortality. Role of terlipressin for the management of liver cirrhosis\u2013related complications has been recognized during recent years. This article aims to develop evidence-based clinical practice guidance on the use of terlipressin for liver cirrhosis\u2013related complications. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> Hepatobiliary Study Group of the Chinese Society of Gastroenterology of the Chinese Medical Association and Hepatology Committee of the Chinese Research Hospital Association have invited gastroenterologists, hepatologists, infectious disease specialists, surgeons, and clinical pharmacists to formulate the clinical practice guidance based on comprehensive literature review and experts\u2019 clinical experiences. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> Overall, 10 major guidance statements regarding efficacy and safety of terlipressin in liver cirrhosis were proposed. Terlipressin can be beneficial for the management of cirrhotic patients with acute variceal bleeding and hepatorenal syndrome (HRS). However, the evidence regarding the use of terlipressin in cirrhotic patients with ascites, post-paracentesis circulatory dysfunction, and bacterial infections and in those undergoing hepatic resection and liver transplantation remains insufficient. Terlipressin-related adverse events, mainly including gastrointestinal symptoms, electrolyte disturbance, and cardiovascular and respiratory adverse events, should be closely monitored. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> The current clinical practice guidance supports the use of terlipressin for gastroesophageal variceal bleeding and HRS in liver cirrhosis. High-quality studies are needed to further clarify its potential effects in other liver cirrhosis\u2013related complications. <\/jats:p><\/jats:sec>","DOI":"10.1177\/17562848221098253","type":"journal-article","created":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T21:02:50Z","timestamp":1652907770000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["Practice guidance for the use of terlipressin for liver cirrhosis\u2013related complications"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9448-6739","authenticated-orcid":false,"given":"Xingshun","family":"Qi","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, General Hospital of Northern Theater Command, 83 Wenhua Road, Shenyang 110015, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaohui","family":"Bai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, General Hospital of Northern Theater Command, Shenyang, China"},{"name":"Department of Life Sciences and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Life Sciences and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"Difficult and Complicated Liver Diseases and Artificial Liver Center, Beijing You\u2019an Hospital, Capital Medical University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaowei","family":"Dang","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiguo","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal and Hepatology, Beijing You\u2019An Hospital, Capital Medical University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juqiang","family":"Han","sequence":"additional","affiliation":[{"name":"Institute of Liver Disease, The 7th Medical Centre of Chinese People Liberation Army General Hospital, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, General Hospital of Northern Theater Command, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingli","family":"He","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, First Affiliated Teaching Hospital, Xi\u2019an Jiaotong University, Xi\u2019an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanpu","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, The Second Affiliated Hospital of Xi\u2019an Jiaotong University, Xi\u2019an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongxu","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, General Hospital of Northern Theater Command, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bimin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyu","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, General Hospital of Northern Theater Command, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3209-8105","authenticated-orcid":false,"given":"Yiling","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, First Affiliated Hospital of China Medical University, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Hepato-Biliary Surgery, Shenzhen Third People\u2019s Hospital, Shenzhen, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Disease, 900 Hospital of the Joint Logistics Team, Fuzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuquan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Interventional Radiology, Beijing Shijitan Hospital, Capital Medical University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Tangdu Hospital of the Fourth Military Medical University, Xi\u2019an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su","family":"Lin","sequence":"additional","affiliation":[{"name":"Liver Research Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dapeng","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, The Sixth People\u2019s Hospital of Dalian, Dalian, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanping","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruizhao","family":"Qi","sequence":"additional","affiliation":[{"name":"Department of General Surgery, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianshu","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lichun","family":"Shao","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Air Force Hospital of Northern Theater Command, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanhong","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, General Hospital of Western Theater Command, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufu","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, General Hospital of Northern Theater Command, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Teng","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, General Hospital of Northern Theater Command, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunhui","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, General Hospital of Northern Theater Command, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, General Hospital of Northern Theater Command, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunhai","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Sixth People\u2019s Hospital of Shenyang, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangbo","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, General Hospital of Northern Theater Command, Shenyang, China"},{"name":"Department of Life Sciences and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinqiu","family":"Yuan","sequence":"additional","affiliation":[{"name":"Clinical Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanshan","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Xi\u2019an Central Hospital, Xi\u2019an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yida","family":"Yang","sequence":"additional","affiliation":[{"name":"Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingchun","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, General Hospital of Northern Theater Command, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongping","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Liver Disease, The Fifth Medical Center of Chinese PLA General Hospital, 100 West Fourth Ring Middle Road, Beijing 100039, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaozhong","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, General Hospital of Northern Theater Command, 83 Wenhua Road, Shenyang 110015, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weifen","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Changzheng Hospital, Naval Medical University, Shanghai 200003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,5,18]]},"reference":[{"key":"bibr1-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.09.014"},{"key":"bibr2-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(19)30349-8"},{"key":"bibr3-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2012.03.032"},{"key":"bibr4-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2010.02272.x"},{"key":"bibr5-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2014.09.004"},{"key":"bibr6-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e3181572357"},{"key":"bibr7-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2006.112177"},{"key":"bibr8-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2010.235473"},{"key":"bibr9-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28264"},{"key":"bibr10-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1080\/00365520310000393"},{"key":"bibr11-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1080\/00365520500292962"},{"key":"bibr12-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2015.07.004"},{"key":"bibr13-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1287\/mnsc.9.3.458"},{"key":"bibr14-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i1152"},{"key":"bibr15-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2004.03877.x"},{"key":"bibr16-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-7843.2006.pto_299.x"},{"key":"bibr17-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-020-06813-w"},{"key":"bibr18-17562848221098253","volume":"1","author":"Ioannou G","year":"2003","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr19-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l321"},{"key":"bibr20-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0b013e328335a35b"},{"key":"bibr21-17562848221098253","doi-asserted-by":"publisher","DOI":"10.2174\/157488408785747728"},{"key":"bibr22-17562848221098253","doi-asserted-by":"publisher","DOI":"10.2147\/JEP.S146034"},{"key":"bibr23-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0676.2000.020001051.x"},{"key":"bibr24-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0901512"},{"key":"bibr25-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.03.024"},{"key":"bibr26-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-010-9236-9"},{"key":"bibr27-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2015.05.022"},{"key":"bibr28-17562848221098253","doi-asserted-by":"publisher","DOI":"10.3109\/00365529009095539"},{"key":"bibr29-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2015-309262"},{"key":"bibr30-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28906"},{"key":"bibr31-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000013437"},{"key":"bibr32-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2005.03902.x"},{"key":"bibr33-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1080\/003655202317316132"},{"key":"bibr34-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.12195"},{"key":"bibr35-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1007\/s12664-018-0871-8"},{"key":"bibr36-17562848221098253","first-page":"203","volume":"32","author":"Chinese Society of Hepatology, Chinese Medical Association; Chinese Society of GastroenteroIogy, Chinese Medical Association; Chinese Society of Endoscopy, Chinese Medical Association","year":"2016","journal-title":"J Clin Hepatol"},{"key":"bibr37-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1007\/s12664-016-0622-7"},{"key":"bibr38-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1055\/a-1187-1154"},{"key":"bibr39-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2018.5"},{"key":"bibr40-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000001524"},{"key":"bibr41-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2011.480"},{"key":"bibr42-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2010.230292"},{"key":"bibr43-17562848221098253","doi-asserted-by":"crossref","first-page":"iv1","DOI":"10.1136\/gut.51.suppl_4.iv1","volume":"51","author":"British Society of Gastroenterology Endoscopy Committee","year":"2002","journal-title":"Gut"},{"key":"bibr44-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2008.01.005"},{"key":"bibr45-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-76530-3"},{"key":"bibr46-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21907"},{"key":"bibr47-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29370"},{"key":"bibr48-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1912484"},{"key":"bibr49-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1211801"},{"key":"bibr50-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2001.27830"},{"key":"bibr51-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1080\/17474124.2019.1694904"},{"key":"bibr52-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(01)68827-5"},{"key":"bibr53-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.13777"},{"key":"bibr54-17562848221098253","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2020.02.135"},{"key":"bibr55-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(97)80247-4"},{"key":"bibr56-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2001.26754"},{"key":"bibr57-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.292.6537.1701"},{"key":"bibr58-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-020-01466-z"},{"key":"bibr59-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000000703"},{"key":"bibr60-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.05.004"},{"key":"bibr61-17562848221098253","first-page":"1310","volume":"56","author":"Salerno F","year":"2007","journal-title":"Gut"},{"key":"bibr62-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2014.12.029"},{"key":"bibr63-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.07.002"},{"key":"bibr64-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2017.05.041"},{"key":"bibr65-17562848221098253","first-page":"1","volume":"27","author":"Zhang J","year":"2019","journal-title":"Shijie Huaren Xiaohua Zazhi"},{"key":"bibr66-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.gastrohep.2021.02.007"},{"key":"bibr67-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1093\/gastro\/goz043"},{"key":"bibr68-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-019-05858-2"},{"key":"bibr69-17562848221098253","volume":"9","author":"Best LM","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr70-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000010431"},{"key":"bibr71-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-017-4178-8"},{"key":"bibr72-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000000913"},{"key":"bibr73-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1080\/17474124.2017.1356223"},{"key":"bibr74-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13912"},{"key":"bibr75-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(16)30157-1"},{"key":"bibr76-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000000537"},{"key":"bibr77-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0107466"},{"key":"bibr78-17562848221098253","doi-asserted-by":"publisher","DOI":"10.4103\/0253-7613.106436"},{"key":"bibr79-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-010-9725-8"},{"key":"bibr80-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2009.06132.x"},{"key":"bibr81-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23286"},{"key":"bibr82-17562848221098253","first-page":"1970","volume":"89","author":"Zhang ZF","year":"2009","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"bibr83-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1177\/039139880903200303"},{"key":"bibr84-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2006.03086.x"},{"key":"bibr85-17562848221098253","volume":"6","author":"Allegretti AS","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr86-17562848221098253","volume":"9","author":"Israelsen M","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr87-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.02.026"},{"key":"bibr88-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(98)80151-7"},{"key":"bibr89-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-007-9919-9"},{"key":"bibr90-17562848221098253","first-page":"34","volume":"2","author":"Pulvirenti D","year":"2008","journal-title":"Ital J Med"},{"key":"bibr91-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.02.014"},{"key":"bibr92-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1746.2003.02934.x"},{"key":"bibr93-17562848221098253","first-page":"123","volume":"7","author":"Yang Y","year":"2001","journal-title":"J Intern Intensive Med"},{"key":"bibr94-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.02.024"},{"key":"bibr95-17562848221098253","doi-asserted-by":"publisher","DOI":"10.14309\/00000434-201210001-00418"},{"key":"bibr96-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27709"},{"key":"bibr97-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2012.01.012"},{"key":"bibr98-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2007.04.010"},{"key":"bibr99-17562848221098253","doi-asserted-by":"crossref","first-page":"13","DOI":"10.4103\/1687-9090.124035","volume":"7","author":"Badawy S","year":"2013","journal-title":"Egypt J Cardiothorac Anesth"},{"key":"bibr100-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(16)01240-X"},{"key":"bibr101-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/liv.12179"},{"key":"bibr102-17562848221098253","first-page":"30","volume":"64","author":"Goyal O","year":"2016","journal-title":"J Assoc Physicians India"},{"key":"bibr103-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2013.02.242"},{"key":"bibr104-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2008.01828.x"},{"key":"bibr105-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2015.08.003"},{"key":"bibr106-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2008290"},{"key":"bibr107-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/apt.15836"},{"key":"bibr108-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28396"},{"key":"bibr109-17562848221098253","first-page":"1847","volume":"33","author":"Chinese Society of Hepatology Chinese Medical Association","year":"2017","journal-title":"J Clin Hepatol"},{"key":"bibr110-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2020-321790"},{"key":"bibr111-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2004.03226.x"},{"key":"bibr112-17562848221098253","doi-asserted-by":"publisher","DOI":"10.3109\/00365521.2010.510576"},{"key":"bibr113-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21901"},{"key":"bibr114-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(97)80456-4"},{"key":"bibr115-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2011.06.013"},{"key":"bibr116-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2016.168"},{"key":"bibr117-17562848221098253","doi-asserted-by":"crossref","first-page":"S501","DOI":"10.1007\/s12072-015-9700-7","volume":"10","author":"Pande G","year":"2016","journal-title":"Hepatol Int"},{"key":"bibr118-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2019.11.010"},{"key":"bibr119-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/5106958"},{"key":"bibr120-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31071"},{"key":"bibr121-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1997.v113.pm9247479"},{"key":"bibr122-17562848221098253","doi-asserted-by":"publisher","DOI":"10.14218\/JCTH.2019.00048"},{"key":"bibr123-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2006.04182.x"},{"key":"bibr124-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1136\/gut.50.1.90"},{"key":"bibr125-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(12)60002-6"},{"key":"bibr126-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2014.01.024"},{"key":"bibr127-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23264"},{"key":"bibr128-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2002.30082"},{"key":"bibr129-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1002\/hep.25532"},{"key":"bibr130-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.3.1016"},{"key":"bibr131-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.06.019"},{"key":"bibr132-17562848221098253","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2019.01492"},{"key":"bibr133-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0129305"},{"key":"bibr134-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000000635"},{"key":"bibr135-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/liv.13252"},{"key":"bibr136-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.12.061"},{"key":"bibr137-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djy184"},{"key":"bibr138-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)30010-2"},{"key":"bibr139-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000003496"},{"key":"bibr140-17562848221098253","doi-asserted-by":"publisher","DOI":"10.20344\/amp.10892"},{"key":"bibr141-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1186\/s12871-019-0779-6"},{"key":"bibr142-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/aas.13226"},{"key":"bibr143-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2020.01.013"},{"key":"bibr144-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.hpb.2019.10.011"},{"key":"bibr145-17562848221098253","doi-asserted-by":"publisher","DOI":"10.21614\/chirurgia.115.6.707"},{"key":"bibr146-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1007\/s00108-008-2268-8"},{"key":"bibr147-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000002305"},{"key":"bibr148-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1998.00004.x"},{"key":"bibr149-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1159\/000185938"},{"key":"bibr150-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1081\/JDI-120022546"},{"key":"bibr151-17562848221098253","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1399-0012.1998.tb01080.x","volume":"12","author":"Bilbao I","year":"1998","journal-title":"Clin Transplant"},{"key":"bibr152-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2015.10.006"},{"key":"bibr153-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000001571"},{"key":"bibr154-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1002\/lt.24759"},{"key":"bibr155-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2013.02.016"},{"key":"bibr156-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3182120842"},{"key":"bibr157-17562848221098253","first-page":"2041","volume":"58","author":"Furgala A","year":"2011","journal-title":"Hepatogastroenterology"},{"key":"bibr158-17562848221098253","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2013.19.4.417"},{"key":"bibr159-17562848221098253","first-page":"71","volume":"45","author":"Nowak L","year":"2004","journal-title":"Folia Med Cracov"},{"key":"bibr160-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.90407.2008"},{"key":"bibr161-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)79315-6"},{"key":"bibr162-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2000.16601"},{"key":"bibr163-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1996.v111.pm8898643"},{"key":"bibr164-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1080\/14740338.2020.1734558"},{"key":"bibr165-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23893"},{"key":"bibr166-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/jcpt.13031"},{"key":"bibr167-17562848221098253","doi-asserted-by":"publisher","DOI":"10.14712\/23362936.2016.7"},{"key":"bibr168-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000000217"},{"key":"bibr169-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1111\/jcpt.13057"},{"key":"bibr170-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.2003.00719.x"},{"key":"bibr171-17562848221098253","first-page":"1","volume":"31","author":"Qi X","year":"2018","journal-title":"Med Inf"},{"key":"bibr172-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e32833a4822"},{"key":"bibr173-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.03.064"},{"key":"bibr174-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1007\/s11739-011-0534-6"},{"key":"bibr175-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200109000-00017"},{"key":"bibr176-17562848221098253","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.891084"},{"key":"bibr177-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2002.35819"},{"key":"bibr178-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2002.32364"},{"key":"bibr179-17562848221098253","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.913150"},{"key":"bibr180-17562848221098253","doi-asserted-by":"publisher","DOI":"10.4318\/tjg.2012.0490"},{"key":"bibr181-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2007.11.009"},{"key":"bibr182-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1159\/000195676"},{"key":"bibr183-17562848221098253","first-page":"381","volume":"51","author":"Oh JE","year":"2008","journal-title":"Korean J Gastroenterol"},{"key":"bibr184-17562848221098253","first-page":"180","volume":"13","author":"Yefet E","year":"2011","journal-title":"Isr Med Assoc J"},{"key":"bibr185-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1016\/S1590-8658(03)00225-1"},{"key":"bibr186-17562848221098253","first-page":"454","volume":"47","author":"Lee JS","year":"2006","journal-title":"Korean J Gastroenterol"},{"key":"bibr187-17562848221098253","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2013.19.2.179"},{"key":"bibr188-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20044"},{"key":"bibr189-17562848221098253","doi-asserted-by":"publisher","DOI":"10.1097\/00005344-199004000-00009"}],"container-title":["Therapeutic Advances in Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17562848221098253","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/17562848221098253","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17562848221098253","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T22:13:54Z","timestamp":1740780834000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/17562848221098253"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":189,"alternative-id":["10.1177\/17562848221098253"],"URL":"https:\/\/doi.org\/10.1177\/17562848221098253","relation":{},"ISSN":["1756-2848","1756-2848"],"issn-type":[{"value":"1756-2848","type":"print"},{"value":"1756-2848","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"article-number":"17562848221098253"}}