{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T18:28:43Z","timestamp":1790188123561,"version":"4.1.0"},"reference-count":33,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82300638"],"award-info":[{"award-number":["82300638"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Zhongda Hospital Affiliated to Southeast University, Jiangsu Province High-Level Hospital Construction Funds","award":["YKK24268"],"award-info":[{"award-number":["YKK24268"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therap Adv Gastroenterol"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec><jats:title>Background:<\/jats:title><jats:p> Refractory esophageal stricture is the common complication of extensive endoscopic submucosal dissection (ESD), without satisfactory endoscopic treatment strategies. We evaluated the efficacy, safety, and long-term patency of the modified endoscopic radial incision and selective cutting combined with short-term stenting (RISC-STS) for the treatment of refractory esophageal stenosis. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> This was a retrospective study. Patients diagnosed with refractory esophageal stricture from June 2016 to June 2023 were enrolled. Efficacy, safety, and risk factors for dysphagia after RISC-STS operation were assessed. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> Compared with clinical symptoms before RISC-STS, there was no significant improvement in the times of stricture recurred ( p\u2009=\u20090.75). However, the narrowest diameter of esophageal stenosis was significantly larger after RISC-STS treatment ( p\u2009=\u20090.04). Corresponding dysphagia scores after RISC-STS were obviously lowered according to the Mellow\u2013Pinkas grading scale ( p\u2009=\u20090.002). More cases ((14 (60.87%) vs 5 (21.74%)) received valid symptom-relief periods after RISC-STS ( p\u2009=\u20090.0004). The complications of RISC-STS include perforation (4.35%), fever (4.35%), and pain (30.43%). Univariate Cox analysis suggested that resection length &gt;7\u2009cm of scar tissue was a risk factor for refractory dysphagia after RISC-STS. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> The present study revealed that RISC-STS is an effective and safe technique for refractory esophageal stricture with lower restenosis, higher valid symptom-relief rate, and fewer complications. <\/jats:p><\/jats:sec>","DOI":"10.1177\/17562848251315416","type":"journal-article","created":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T11:12:26Z","timestamp":1738321946000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Utility of modified endoscopic radial incision and selective cutting combined with short-term stenting for refractory stricture in patients undergoing endoscopic submucosal dissection of superficial esophageal carcinoma"],"prefix":"10.1177","volume":"18","author":[{"given":"Lu","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiajiao","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjing","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"XiaoChun","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, 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