{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T08:19:34Z","timestamp":1775204374937,"version":"3.50.1"},"reference-count":16,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Competence Network IBD"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therap Adv Gastroenterol"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:p>The Competence Network Inflammatory Bowel Diseases (Kompetenznetz Darmerkrankungen) was established in Germany in 1999 through a 10-year funding programme by the German Ministry of Education and Research. It was created to address the growing gap between the rising prevalence and therapeutic complexity of inflammatory bowel disease (IBD) and the fragmented care structures and isolated academic initiatives of the time. The network\u2019s continuing mission is to improve care for patients with Crohn\u2019s disease and ulcerative colitis by more closely integrating clinical practice, translational science and patient involvement. This review summarises the history, governance, registries, biobanking, clinical trials, educational programmes and collaborations of the Competence Network IBD. Over the past 25\u2009years, the Competence Network IBD has established prospective national registries (e.g. RUN-CD, RUN-UC, VEDO-IBD and FilgoColitis), developed pragmatic real-world cohorts (TARGET and GeCer) and contributed to the UMBRELLA-IBD data warehouse of the Competence Network IBD in Germany. The network played a central role in creating the German IBD DNA collection and supported the Kiel University biobank, both of which link biospecimens with longitudinal clinical data to support genetic and microbiome research. It also conducts and coordinates multicentre clinical trials and has supported the development of the German evidence- and consensus-based IBD guidelines. With more than 800 members from university centres, community practices, nursing and patient organisations, it now provides a robust platform for research and knowledge transfer across all levels of IBD care. The Competence Network IBD demonstrates how long-term interdisciplinary and cross-sectoral collaboration can improve the management of chronic inflammatory diseases. By integrating research infrastructures with education and patient involvement, the network serves as a scalable and sustainable model for national and international collaboration in IBD.<\/jats:p>","DOI":"10.1177\/17562848261431187","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T06:10:32Z","timestamp":1774937432000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Competence network inflammatory bowel diseases in Germany: 25\u2009years of interdisciplinary and cross-sectoral research and knowledge transfer across all levels of IBD care"],"prefix":"10.1177","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2016-6991","authenticated-orcid":false,"given":"Bernd","family":"Bokemeyer","sequence":"first","affiliation":[{"name":"Interdisciplinary Crohn Colitis Centre Minden, M\u00e4rchenweg 17, Minden 32429, Germany"},{"name":"Department Medicine I, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany"},{"name":"Competence Network IBD, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Plachta-Danielzik","sequence":"additional","affiliation":[{"name":"Competence Network IBD, Kiel, Germany"},{"name":"Institute of Human Nutrition and Food Science, Kiel University, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulf","family":"Helwig","sequence":"additional","affiliation":[{"name":"Department Medicine I, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany"},{"name":"Competence Network IBD, Kiel, Germany"},{"name":"Gastroenterology Practice, Oldenburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Beuchert","sequence":"additional","affiliation":[{"name":"Competence Network IBD, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Schreiber","sequence":"additional","affiliation":[{"name":"Department Medicine I, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany"},{"name":"Competence Network IBD, Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,3,30]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00103-016-2317-8"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.10.020"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2015.34"},{"issue":"12","key":"e_1_3_4_5_2","first-page":"1397","article-title":"National research networks in IBD","volume":"42","author":"Bokemeyer B","year":"2004","unstructured":"Bokemeyer B, Schreiber S. 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Z Gastroenterol 2024; 62: 769\u2013858.","journal-title":"Z Gastroenterol"},{"key":"e_1_3_4_8_2","first-page":"1012","article-title":"Real-world evidence data warehouse for pooled analyses in patients with inflammatory bowel diseases in Germany: the \u2018Umbrella-IBD Registry\u2019 of the Competence Network IBD","volume":"11","author":"Bokemeyer B","year":"2023","unstructured":"Bokemeyer B, Plachta-Danielzik S, Wenske T, et al. Real-world evidence data warehouse for pooled analyses in patients with inflammatory bowel diseases in Germany: the \u2018Umbrella-IBD Registry\u2019 of the Competence Network IBD. United Eur Gastroenterol J 2023; 11(Suppl. 8): 1012.","journal-title":"United Eur Gastroenterol J"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/apt.17512"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/apt.17616"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izad138"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjaf051"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjaf052"},{"key":"e_1_3_4_14_2","article-title":"TARGET registry","volume":"61","author":"Plachta-Danielzik S","year":"2023","unstructured":"Plachta-Danielzik S, Bokemeyer B, Tappe U, et al. TARGET registry. 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