{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T06:49:16Z","timestamp":1777013356754,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therap Adv Gastroenterol"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Malnutrition is common in patients with pancreatic head cancer, which can diminish their tolerance to anti-cancer treatments. Pancreatic duct blockage is one of the contributing factors leading to malnutrition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>This study aimed to clarify whether pancreatic stenting offers a survival benefit in patients with unresected pancreatic head cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Retrospective observational study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Patients with newly diagnosed pancreatic cancers who received endoscopic retrograde cholangiopancreatography (ERCP) because of biliary tract obstruction were collected from a hospital-based cancer registry between 2007 and 2021. Individuals who underwent tumor resection or bypass surgery following ERCP were excluded. The primary outcome was the 1-year survival rate in patients with and without a pancreatic stent. Secondary outcomes included overall survival, cancer-specific survival, and changes in weight and nutritional markers following ERCP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Among 562 patients, 39 (6.9%) received pancreatic stent placement. Most of the patients (90%) did not receive tumor resection because of advanced-stage disease. The stent group had a lower 1-year survival rate than the non-stent group (18% vs 30%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.047). The median survival time appeared to be shorter in the stent group (170 vs 217\u2009days;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.077). The adjusted hazard ratio of pancreatic stent placement was 1.42 (95% confidence interval, 0.75\u20132.67;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.282). In addition, changes in weight and nutritional markers after ERCP did not differ significantly between the groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Pancreatic stent placement in unresected pancreatic head cancer with obstructive jaundice does not improve survival or nutritional status.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17562848261437173","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T11:17:37Z","timestamp":1776770257000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Survival impact of pancreatic stenting in unresected pancreatic head cancer with obstructive jaundice: a retrospective cohort study"],"prefix":"10.1177","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6202-1320","authenticated-orcid":false,"given":"Weng-Fai","family":"Wong","sequence":"first","affiliation":[{"name":"Division of Ultrasound, Department of Integrated Diagnostics &amp; Therapeutics, National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Ting","family":"Kuo","sequence":"additional","affiliation":[{"name":"Division of Endoscopy, Department of Integrated Diagnostics &amp; Therapeutics, National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan"},{"name":"Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Lun","family":"Han","sequence":"additional","affiliation":[{"name":"Division of Endoscopy, Department of Integrated Diagnostics &amp; Therapeutics, National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan"},{"name":"Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2953-210X","authenticated-orcid":false,"given":"Chieh-Chang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan"},{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsiu-Po","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital. No. 7, Chung-Shan South Road, Taipei 100225, Taiwan"},{"name":"Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,4,21]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-73525-y"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.14740\/wjon1166"},{"issue":"1","key":"e_1_3_4_4_2","first-page":"6193765","article-title":"Assessment of nutritional status, digestion and absorption, and quality of life in patients with locally advanced pancreatic cancer","volume":"2017","author":"Witvliet-van Nierop JE","year":"2017","unstructured":"Witvliet-van Nierop JE, Lochtenberg-Potjes CM, Wierdsma NJ, et al. Assessment of nutritional status, digestion and absorption, and quality of life in patients with locally advanced pancreatic cancer. 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