{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T06:29:29Z","timestamp":1781504969349,"version":"3.54.1"},"reference-count":33,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ther Adv Neurol Disord"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec><jats:title>Background:<\/jats:title><jats:p> Spinal cord infarction (SCI) is a neurological emergency associated with high rates of persistent neurological deficits. Knowledge about this rare but potentially treatable condition needs to be expanded. <\/jats:p><\/jats:sec><jats:sec><jats:title>Objective:<\/jats:title><jats:p> To describe the characteristics of spontaneous SCI in a large retrospective series of patients treated at two tertiary care centers in Austria. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> We performed a descriptive and comparative analysis of spontaneous SCI treated at the University Hospitals of Salzburg and Graz between the years 2000 and 2020. The analysis included pre- and in-hospital procedures, clinical presentation, etiology, diagnostic certainty, reperfusion therapy, and functional outcome at discharge. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> We identified 88 cases, 61% were ascertained in the second half of the study period. The median age was 65.5\u2009years [interquartile range (IQR)\u2004=\u200456\u201374], 51.1% were women. Anterior spinal artery infarction was the predominant syndrome (82.9%). Demographics, vascular comorbidities, and clinical presentation did not differ between the centers. The most frequent etiology and level of diagnostic certainty were distinct, with atherosclerosis (50%) and definite SCI (42%), and unknown (52.5%) and probable SCI (60%) as front runners in Salzburg and Graz, respectively. Patients arrived after a median of 258.5\u2009min (IQR\u2004=\u2004110\u2013528) at the emergency room. The first magnetic resonance imaging (MRI) of the spinal cord was performed after a median of 148\u2009min (IQR\u2004=\u200490\u2013312) from admission and was diagnostic for SCI in 45%. Two patients received intravenous thrombolysis (2.2%). The outcome was poor in 37\/77 (48%). <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> Demographics, clinical syndromes, and quality benchmarks for spontaneous SCI were consistent at two Austrian tertiary care centers. Our findings provide the foundation for establishing standards for pre- and in-hospital care to improve outcomes. <\/jats:p><\/jats:sec>","DOI":"10.1177\/17562864221076321","type":"journal-article","created":{"date-parts":[[2022,3,11]],"date-time":"2022-03-11T12:00:56Z","timestamp":1647000056000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Spontaneous spinal cord infarction in Austria: a two-center comparative study"],"prefix":"10.1177","volume":"15","author":[{"given":"Slaven","family":"Pikija","sequence":"first","affiliation":[{"name":"Department of Neurology, Christian Doppler Medical Center, Paracelsus Medical University, Salzburg, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander B.","family":"Kunz","sequence":"additional","affiliation":[{"name":"Department of Neurology, Christian Doppler Medical Center, Paracelsus Medical University, Salzburg, Austria"},{"name":"Karl Landsteiner Institute for Neurorehabilitation and Space Neurology, Salzburg, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Nardone","sequence":"additional","affiliation":[{"name":"Karl Landsteiner Institute for Neurorehabilitation and Space Neurology, Salzburg, Austria"},{"name":"Department of Neurology, Hospital of Merano (SABES-ASDAA), Merano, Italy; Spinal Cord Injury and Tissue Regeneration Center, Salzburg, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Enzinger","sequence":"additional","affiliation":[{"name":"Department of Neurology, Medical University of Graz, Graz, Austria"},{"name":"Division of Neuroradiology, Vascular and Interventional Radiology, Department of Radiology, Medical University of Graz, Graz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes 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