{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:58:57Z","timestamp":1792799937665,"version":"4.5.0"},"reference-count":11,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"The Natural Science Foundation of Jiangsu Province","award":["BK20231158"],"award-info":[{"award-number":["BK20231158"]}]},{"name":"Postgraduate Research & Practice Innovation Program of Jiangsu Province","award":["SJCX23_1393"],"award-info":[{"award-number":["SJCX23_1393"]}]},{"name":"The Open Project of Key Laboratory of Colleges and Universities in Jiangsu Province","award":["XZSYSKF2021041"],"award-info":[{"award-number":["XZSYSKF2021041"]}]},{"name":"Medical research project of Jiangsu Provincial Health Commission","award":["M2022118"],"award-info":[{"award-number":["M2022118"]}],"id":[{"id":"https:\/\/ror.org\/03eqskn19","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ther Adv Neurol Disord"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Myasthenia gravis (MG) is an autoimmune disorder characterized by fluctuating muscle weakness. Severe patients may develop life-threatening respiratory failure and experience crisis. Plasma exchange or intravenous immunoglobulin (IVIg) is the first-line treatment option for myasthenia crisis, but some patients still poorly respond to them. Here, we first reported a generalized MG patient from China who was in a state of impending myasthenic crisis and did not respond effectively to IVIg but was successfully rescued by add-on efgartigimod. Especially, we also detected meaningful changes in T-cell and B-cell subsets after efgartigimod, promoting a potential role of efgartigimod in re-establishing immune homeostasis.<\/jats:p>","DOI":"10.1177\/17562864241254895","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T08:08:55Z","timestamp":1716883735000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["Rescue treatment with add-on efgartigimod in a patient with impending myasthenic crisis: a case report"],"prefix":"10.1177","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6253-6167","authenticated-orcid":false,"given":"Zhouao","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Neurology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 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