{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T12:52:52Z","timestamp":1787662372599,"version":"build-2736575974"},"reference-count":29,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Urology"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec><jats:title>Background:<\/jats:title><jats:p> We aim to evaluate the distribution in the upper urinary tract of intravesical-delivered fluids, after inducing vesicoureteral reflux (VUR) with a double J stent. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> In group 1 ( n = 35) patients were maintained in a 20\u00b0 Trendelenburg position and were evaluated after immediate insertion of ureteral stent, while in group 2 ( n = 16) patients were evaluated after several days with ureteral stent placement. Patients in both groups were submitted to a cystogram with progressive volumes of iodine contrast and were evaluated according to VUR of contrast medium to the renal pelvis. Additionally, in group 2 visual confirmation was performed by endoscopic inspection of upper tract mucosal impregnation with methylene blue. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> In group 1, after immediate insertion of ureteral stent reflux occurred in 51.4% ( n = 18\/35), and after several days with ureteral stent placement reflux was observed in 87.5% ( n = 14\/16) of patients. Reflux was progressively more frequent according to increasing bladder volume ( p &lt; 0.001). At 60\u2009ml bladder volume no reflux was observed, while at 120\u2009ml, 180\u2009ml, 240\u2009ml, 300\u2009ml and 360\u2009ml bladder volume reflux was observed in 14%, 25%, 41%, 55% and 63% of patients, respectively. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> Retrograde delivery of fluids such as bacillus Calmette-Gu\u00e9rin to the upper urinary tract through double J stents can be effective; however, it is mainly effective after several days with ureteral stent and relatively large volumes might be instilled into the bladder. <\/jats:p><\/jats:sec>","DOI":"10.1177\/1756287219836895","type":"journal-article","created":{"date-parts":[[2019,3,27]],"date-time":"2019-03-27T20:41:23Z","timestamp":1553719283000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Is ureteral stent an effective way to deliver drugs such as bacillus Calmette-Gu\u00e9rin to the upper urinary tract? An experimental study"],"prefix":"10.1177","volume":"11","author":[{"given":"Fernando","family":"Korkes","sequence":"first","affiliation":[{"name":"Discipline of Urology, Faculdade de Medicina do ABC, Santo Andr\u00e9, SP, Brazil Division of Urology, Hospital Israelita Albert Einstein, S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8653-3913","authenticated-orcid":false,"given":"Willy","family":"Baccaglini","sequence":"additional","affiliation":[{"name":"Discipline of Urology \u2013 Faculdade de Medicina do ABC, Av. Lauro Gomes, 2000 \u2013 Anexo II, Vila Sacadura Cabral \u2013 Santo Andr\u00e9, SP, CEP: 09060-870, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel Aranha","family":"Silveira","sequence":"additional","affiliation":[{"name":"Discipline of Urology, Faculdade de Medicina do ABC, Santo Andr\u00e9, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,3,27]]},"reference":[{"key":"bibr1-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1016\/j.eursup.2008.07.009"},{"key":"bibr2-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2013.03.032"},{"key":"bibr3-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2012.11068.x"},{"key":"bibr4-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)58737-6"},{"key":"bibr5-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)47277-6"},{"key":"bibr6-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20348"},{"key":"bibr7-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1159\/000052391"},{"key":"bibr8-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24135"},{"key":"bibr9-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1159\/000350508"},{"key":"bibr10-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2004.01.046"},{"key":"bibr11-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)38957-7"},{"key":"bibr12-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)64454-0"},{"key":"bibr13-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)36117-7"},{"key":"bibr14-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2011.07.051"},{"key":"bibr15-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)34860-7"},{"key":"bibr16-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000132128.79974.db"},{"key":"bibr17-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)64015-1"},{"key":"bibr18-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)37980-6"},{"key":"bibr19-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(01)01488-1"},{"key":"bibr20-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-012-0949-3"},{"key":"bibr21-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1089\/end.2008.0164"},{"key":"bibr22-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1007\/BF00184116"},{"key":"bibr23-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000147747.89028.64"},{"key":"bibr24-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1590\/S1677-55382006000600005"},{"key":"bibr25-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)45194-9"},{"key":"bibr26-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)35867-6"},{"key":"bibr27-1756287219836895","first-page":"27","volume":"157","author":"Homma Y","year":"1994","journal-title":"Scand J Urol Nephrol Suppl"},{"key":"bibr28-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1520-6777(1999)18:1<3::AID-NAU2>3.0.CO;2-4"},{"key":"bibr29-1756287219836895","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)36572-2"}],"container-title":["Therapeutic Advances in Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1756287219836895","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1756287219836895","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1756287219836895","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T07:28:23Z","timestamp":1740814103000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1756287219836895"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":29,"alternative-id":["10.1177\/1756287219836895"],"URL":"https:\/\/doi.org\/10.1177\/1756287219836895","relation":{},"ISSN":["1756-2872","1756-2880"],"issn-type":[{"value":"1756-2872","type":"print"},{"value":"1756-2880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1]]},"article-number":"1756287219836895"}}