{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T23:35:21Z","timestamp":1792712121661,"version":"4.5.0"},"reference-count":12,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Urology"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p> Pulmonary lymphangioleiomyomatosis (LAM), a rare, progressive disease predominantly affecting the lungs of women of reproductive age, is often associated with renal angiomyolipoma (AML). We report the case of a 29-year-old female patient who presented to our obstetrics department at 37\u2009weeks\u2019 gestation, complaining of abdominal pain, and constipation. Ultrasound noted a viable singleton with a large left-sided abdominal mass. After undergoing a caesarean section, she was referred to our urology department to assess her flank mass further. Computed tomography demonstrated a large, exophytic left renal mass measuring 22 cm x 16 cm x 13\u2009cm, suggestive of an AML and numerous bilateral pulmonary cysts. A diagnosis of LAM and associated unilateral giant renal AML was made. As soon as she had fully recovered from her caesarean section, we removed the huge AML via a standard left-sided open nephrectomy without incident. We report this rare case of giant AML associated with LAM and review the literature about the association of these two conditions. <\/jats:p>","DOI":"10.1177\/17562872211069700","type":"journal-article","created":{"date-parts":[[2022,1,20]],"date-time":"2022-01-20T06:06:35Z","timestamp":1642658795000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Pulmonary lymphangioleiomyomatosis with an associated giant renal angiomyolipoma"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6139-810X","authenticated-orcid":false,"given":"Jeff","family":"John","sequence":"first","affiliation":[{"name":"Division of Urology, Department of Surgery, Frere Hospital and Walter Sisulu University, East London 5200, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro Pietro","family":"Aldera","sequence":"additional","affiliation":[{"name":"Division of Anatomical Pathology, University of Cape Town, Cape Town, South Africa; JDW Pathology Incorporated, Cape Town, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dap","family":"Louw","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery, Frere Hospital and Walter Sisulu University, East London, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Lazarus","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Kesner","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery, Frere Hospital and Walter Sisulu University, East London, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,1,19]]},"reference":[{"key":"bibr1-17562872211069700","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-021-01776-7"},{"key":"bibr2-17562872211069700","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1325159"},{"key":"bibr3-17562872211069700","doi-asserted-by":"publisher","DOI":"10.4322\/acr.2013.040"},{"key":"bibr4-17562872211069700","doi-asserted-by":"publisher","DOI":"10.5334\/jbsr.1536"},{"key":"bibr5-17562872211069700","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2013.08.001"},{"key":"bibr6-17562872211069700","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201709-1965ST"},{"key":"bibr7-17562872211069700","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(03)00006-4"},{"key":"bibr8-17562872211069700","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200409-1298OC"},{"key":"bibr9-17562872211069700","first-page":"298","volume":"7","author":"Chen P","year":"2017","journal-title":"Mol Clin Oncol"},{"key":"bibr10-17562872211069700","first-page":"36","volume":"8","author":"Phillips CK","year":"2006","journal-title":"Rev Urol"},{"key":"bibr11-17562872211069700","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2251011477"},{"key":"bibr12-17562872211069700","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-019-1178-2"}],"container-title":["Therapeutic Advances in Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17562872211069700","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/17562872211069700","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17562872211069700","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T14:12:43Z","timestamp":1740838363000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/17562872211069700"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":12,"alternative-id":["10.1177\/17562872211069700"],"URL":"https:\/\/doi.org\/10.1177\/17562872211069700","relation":{},"ISSN":["1756-2872","1756-2880"],"issn-type":[{"value":"1756-2872","type":"print"},{"value":"1756-2880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"article-number":"17562872211069700"}}