{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T13:36:40Z","timestamp":1753882600721,"version":"3.41.2"},"reference-count":40,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Urology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec><jats:title>Background:<\/jats:title><jats:p> The pharmacological treatment of urinary incontinence (UI) may involve bladder antimuscarinics, which can generate risks in the elderly. <\/jats:p><\/jats:sec><jats:sec><jats:title>Objective:<\/jats:title><jats:p> The aim was to determine the treatment patterns of a group of patients with UI and possible potentially inappropriate prescriptions. <\/jats:p><\/jats:sec><jats:sec><jats:title>Design and methods:<\/jats:title><jats:p> This was a cross-sectional study that identified prescription patterns of medications for outpatient use in patients with UI between December 2020 and November 2021 based on a population database of members of the Colombian Health System. Patients were identified based on the codes of the international classification of diseases, version-10. Sociodemographic and pharmacological variables were considered. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> A total of 9855 patients with UI were identified, with a median age of 72 years, and 74.6% were women. Unspecified UI was the most frequent form (83.2%), followed by specified UI (7.9%), stress UI (6.7%), and UI associated with an overactive bladder (2.2%). A total of 37.2% received pharmacological treatment, mainly with bladder antimuscarinics (22.6%), mirabegron (15.6%), and topical estrogens (7.9%). Pharmacological management predominated in UI associated with overactive bladder, in women and in patients between 50 and 79 years of age. Of the patients who received bladder antimuscarinics, 54.5% were 65 years old or older, and 21.5% also had benign prostatic hyperplasia, sicca syndrome, glaucoma, constipation, or dementia. A total of 2.0% of women had been prescribed systemic estrogens and 1.7% had been prescribed peripheral \u03b1-adrenergic antagonists. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> Differences in the prescriptions were found according to the type of UI, sex, and age group. Potentially inappropriate or risky prescriptions were common. <\/jats:p><\/jats:sec>","DOI":"10.1177\/17562872231179104","type":"journal-article","created":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T09:31:51Z","timestamp":1686907911000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Patterns of use of medications used to treat urinary incontinence and potentially inappropriate prescriptions"],"prefix":"10.1177","volume":"15","author":[{"given":"Luis Fernando","family":"Valladales-Restrepo","sequence":"first","affiliation":[{"name":"Grupo de Investigaci\u00f3n de Farmacoepidemiolog\u00eda y Farmacovigilancia, Universidad Tecnol\u00f3gica de Pereira and Audifarma S.A., Pereira, Colombia"},{"name":"Grupo de Investigaci\u00f3n Biomedicina, Facultad de Medicina, Fundaci\u00f3n Universitaria Aut\u00f3noma de las Am\u00e9ricas, Pereira, Colombia"},{"name":"Semillero de Investigaci\u00f3n en Farmacolog\u00eda Geri\u00e1trica, Facultad de Medicina, Fundaci\u00f3n Universitaria Aut\u00f3noma de las Am\u00e9ricas, Pereira, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo Alejandro","family":"Bedoya-Arias","sequence":"additional","affiliation":[{"name":"Grupo de Investigaci\u00f3n de Farmacoepidemiolog\u00eda y Farmacovigilancia, Universidad Tecnol\u00f3gica de Pereira and Audifarma S.A., Pereira, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brayan Stiven","family":"Aristiz\u00e1bal-Carmona","sequence":"additional","affiliation":[{"name":"Semillero de Investigaci\u00f3n en Farmacolog\u00eda Geri\u00e1trica, Facultad de Medicina, Fundaci\u00f3n Universitaria Aut\u00f3noma de las Am\u00e9ricas, Pereira, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8455-0936","authenticated-orcid":false,"given":"Jorge Enrique","family":"Machado-Alba","sequence":"additional","affiliation":[{"name":"Grupo de Investigaci\u00f3n de Farmacoepidemiolog\u00eda y Farmacovigilancia, Universidad Tecnol\u00f3gica de Pereira and Audifarma S.A., Calle 105 No. 14-140, Pereira 660003, Risaralda, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,6,16]]},"reference":[{"key":"bibr1-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1002\/nau.24509"},{"key":"bibr2-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-009-0976-9"},{"key":"bibr3-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2017.12.031"},{"key":"bibr4-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1080\/13697137.2018.1543263"},{"key":"bibr5-17562872231179104","volume":"12","author":"Alshammari S","year":"2020","journal-title":"Cureus"},{"key":"bibr6-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1111\/bju.13187"},{"key":"bibr7-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2010.03006.x"},{"key":"bibr8-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.15767"},{"key":"bibr9-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2012.02.2575"},{"key":"bibr10-17562872231179104","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2021.788642"},{"key":"bibr11-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000000309"},{"key":"bibr12-17562872231179104","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1093\/ageing\/afx178","volume":"47","author":"O\u2019Mahony D","year":"2018","journal-title":"Age Ageing"},{"key":"bibr13-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2318-13-57"},{"key":"bibr14-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.13713"},{"key":"bibr15-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000468"},{"key":"bibr16-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrtlng.2012.08.003"},{"key":"bibr17-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2013.08.017"},{"key":"bibr18-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0204456"},{"key":"bibr19-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogc.2019.04.010"},{"key":"bibr20-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-020-05315-1"},{"key":"bibr21-17562872231179104","doi-asserted-by":"publisher","DOI":"10.1177\/0300060520931348"},{"key":"bibr22-17562872231179104","unstructured":"Organizaci\u00f3n Mundial de la Salud. 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