{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T02:10:03Z","timestamp":1781921403685,"version":"3.54.5"},"reference-count":24,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Urology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To review outcomes for patients with irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD) who undergo holmium laser enucleation of prostate (HoLEP) for bothersome urinary symptoms related to benign prostatic hyperplasia (BPH).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      We performed a retrospective review of patients who had undergone HoLEP by a single surgeon between January 2021 and August 2023. Preoperative, intraoperative, and postoperative characteristics were compared between patients with an ICD-10 diagnosis of IBS or IBD and those without, using Chi-square and paired\n                      <jats:italic toggle=\"yes\">T<\/jats:italic>\n                      -tests as appropriate.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Out of 918 men, 24 (2.6%) had a diagnosis of IBS, and 36 (3.9%) had a diagnosis of IBD. There were no differences in age, BMI, preoperative American Urological Association symptoms score (AUASS), preoperative Michigan Incontinence Symptom Index (MISI) score, and history of urinary retention or incontinence. The IBS\u2009+\u2009IBD cohort had smaller prostates (100.9 vs 124.2\u2009mL,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.01) and shorter procedure times (57.0 vs 66.5\u2009min,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.02) than controls. IBS patients were more likely to require anticholinergic therapy at a 3-month follow-up (31% vs 13%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.03) and had more postoperative encounters within 90\u2009days of HoLEP (3.7 vs 2.6,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.01). There were no differences regarding changes in AUASS and MISI scores, same-day trial of void and same-day discharge rates, or complication rates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>IBS patients who underwent HoLEP had more symptomatic postoperative courses requiring higher rates of anticholinergic medication use and more provider interactions compared to men without IBS, despite similar AUASS and MISI scores. These trends were not observed in patients with IBD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17562872251317918","type":"journal-article","created":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T04:24:04Z","timestamp":1739420644000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Do Bowel Disorders Affect Holmium Laser Enucleation of Prostate Outcomes? A Retrospective Cohort Study"],"prefix":"10.1177","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6424-052X","authenticated-orcid":false,"given":"Kyle","family":"Tsai","sequence":"first","affiliation":[{"name":"Department of Urology, Northwestern University Feinberg School of Medicine, 676 N. St. Clair, Suite 2300, Chicago, IL 60611, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Perry","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5959-2966","authenticated-orcid":false,"given":"Jenny","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Dean","sequence":"additional","affiliation":[{"name":"Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA"},{"name":"Division of Urology, University of Alberta, Edmonton, AB, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nabila","family":"Khondakar","sequence":"additional","affiliation":[{"name":"Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clayton","family":"Neill","sequence":"additional","affiliation":[{"name":"Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Krambeck","sequence":"additional","affiliation":[{"name":"Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,2,13]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2018.06.010"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10522-015-9554-3"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.02.020"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.12028"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2013.11019.x"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOG.0000000000000070"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2016.141"},{"key":"e_1_3_5_9_2","first-page":"13","article-title":"Holmium laser enucleation of the prostate (HoLEP): a review and update","volume":"26","author":"Das AK","year":"2019","unstructured":"Das AK, Teplitsky S, Humphreys MR. Holmium laser enucleation of the prostate (HoLEP): a review and update. Canadian J Urol 2019; 26(4 Suppl. 1): 13\u201319.","journal-title":"Canadian J Urol"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.2021.0531"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)36966-5"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22468"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.27.9.1014"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410X.1997.00172.x"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2009.02442.x"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2012.11591.x"},{"issue":"2","key":"e_1_3_5_17_2","first-page":"130","article-title":"Change in functional bowel symptoms after prostatectomy: a case-control study","volume":"16","author":"Adibi P","year":"2011","unstructured":"Adibi P, Mazdak H, Derakhshandeh A, et al. Change in functional bowel symptoms after prostatectomy: a case-control study. J Res Med Sci 2011; 16(2): 130\u2013135.","journal-title":"J Res Med Sci"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00182658"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1159\/000052410"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12301-021-00122-4"},{"issue":"4","key":"e_1_3_5_21_2","first-page":"155798832211132","article-title":"The efficacy and safety of HoLEP for benign prostatic hyperplasia with large volume: a systematic review and meta-analysis","volume":"16","author":"Sun F","year":"2022","unstructured":"Sun F, Yao H, Bao X, et al. The efficacy and safety of HoLEP for benign prostatic hyperplasia with large volume: a systematic review and meta-analysis. Am J Men\u2019s Health 2022; 16(4): 15579883221113203.","journal-title":"Am J Men"},{"key":"e_1_3_5_22_2","first-page":"104280","article-title":"Comparative efficacy and safety of holmium laser enucleation of the prostate (HoLEP) using moses technology and standard HoLEP: a systematic review, meta-analysis, and meta-regression","volume":"81","author":"Ramadhani MZ","year":"2012","unstructured":"Ramadhani MZ, Kloping YP, Rahman IA, et al. Comparative efficacy and safety of holmium laser enucleation of the prostate (HoLEP) using moses technology and standard HoLEP: a systematic review, meta-analysis, and meta-regression. Ann Med Surg 2012, 81: 104280.","journal-title":"Ann Med Surg"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.2020.1218"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1590\/s1677-5538.ibju.2019.0411"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12894-019-0570-5"}],"container-title":["Therapeutic Advances in Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17562872251317918","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/17562872251317918","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/17562872251317918","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T21:10:59Z","timestamp":1767647459000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/17562872251317918"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":24,"alternative-id":["10.1177\/17562872251317918"],"URL":"https:\/\/doi.org\/10.1177\/17562872251317918","relation":{},"ISSN":["1756-2872","1756-2880"],"issn-type":[{"value":"1756-2872","type":"print"},{"value":"1756-2880","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"article-number":"17562872251317918"}}