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However, there have been few studies focusing on the role of reTURB after en bloc resection of bladder tumor (ERBT) for NMIBC by far. This study aimed to evaluate whether reTURB can be avoided after ERBT.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Materials and methods:<\/jats:title>\n            <jats:p>We conducted research in PubMed, Web of Science, EMBASE, and the Cochrane Library up to November 14, 2024, to identify studies on the reTURB after initial ERBT. For data conversion and the combined calculation of the incidence rate, we utilized R software (R Foundation for Statistical Computing, Vienna, Austria) and Cochrane Review Manager 5.4 (The Cochrane Collaboration, London, UK) along with the double arcsine method. This systematic review protocol was registered at the International Prospective Register of Systematic Reviews (PROSPERO) under number 1082989.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>\n              A total of 17 studies involving 1051 participants were included. The rates of residual tumor and tumor upstaging detected by reTURB or cystoscopy after ERBT were 9% (95% confidence interval (CI)\u2009=\u20094%\u201316%) and 0% (95% CI\u2009=\u20090%\u20131%). No statistically significant positive effect of reTURB after initial ERBT was exhibited in recurrence-free survival (RFS), tumor recurrence, and progression. The pooled hazard ratios of 1-year and 5-year RFS were 0.77 (95% CI\u2009=\u20090.41\u20131.44,\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.41) and 0.83 (95% CI\u2009=\u20090.58\u20131.20,\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.33). The pooled odds ratio of progression and recurrence were 1.13 (95% CI\u2009=\u20090.53\u20132.41,\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.75) and 0.78 (95%\u2009CI\u2009=\u20090.53\u20131.16,\n              <jats:italic>p<\/jats:italic>\n              \u2009=\u20090.23).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion:<\/jats:title>\n            <jats:p>ERBT can successfully regulate the rate of tumor upstaging and residual tumor to an acceptable level. For patients with NMIBC, subsequent reTURB may not be required following the initial ERBT.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1177\/17562872251367555","type":"journal-article","created":{"date-parts":[[2025,9,7]],"date-time":"2025-09-07T12:57:12Z","timestamp":1757249832000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluating repeat transurethral resection after en bloc resection for non-muscle invasive bladder cancer"],"prefix":"10.1177","volume":"17","author":[{"given":"Jincong","family":"Li","sequence":"first","affiliation":[{"name":"Department of Urology, Peking University People\u2019s Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuxuan","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University People\u2019s Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University People\u2019s Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanlin","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University People\u2019s Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University People\u2019s Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University People\u2019s Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jilin","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University People\u2019s Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shicong","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University People\u2019s Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiqing","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University People\u2019s Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caipeng","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University People\u2019s Hospital, 11 Xizhimen South Street, Haidian District, Beijing 100044, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3899-1500","authenticated-orcid":false,"given":"Tao","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Urology, Peking University People\u2019s Hospital, 11 Xizhimen South Street, Haidian District, Beijing 100044, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,9,7]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-019-02984-4"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgh-2020-004128"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2023.08.016"},{"issue":"1","key":"e_1_3_4_5_2","first-page":"12","article-title":"Global burden and cross-country inequalities in urinary tumors from 1990 to 2021 and predicted incidence changes to 2046","volume":"12","author":"Feng DC","year":"2025","unstructured":"Feng DC, Li DX, Wu RC, et al. 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