{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T08:18:43Z","timestamp":1775204323092,"version":"3.50.1"},"reference-count":22,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Urology"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Ureteral rest refers to the removal of hardware across a ureteral stricture, allowing for stricture maturation and stabilization, before ureteral reconstruction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>We aimed to assess the potential impact of ureteral rest on lower urinary tract symptoms (LUTS) and health-related quality of life (HRQOL) in patients undergoing ureteral rest.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>Prospective, longitudinal, self-controlled study<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We included patients undergoing ureteral reconstruction between April 2022 and April 2025. We defined ureteral rest as replacing an indwelling double-J stent (DJS) with a percutaneous nephrostomy tube (PCN) prior to ureteral reconstruction. Primary outcomes were patient-reported LUTS (via International Prostate Symptom Score) and HRQOL (via Patient-Reported Outcomes Measurement Information System 29 v2.0). The secondary outcome was the incidence of urinary tract infections (UTIs). Questionnaires were completed prior to initiating ureteral rest (with a DJS) and after at least 3\u2009weeks of ureteral rest (with a PCN). Continuous and categorical variables were compared using paired t-tests and chi-squared tests, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Thirty-five patients met our study\u2019s inclusion criteria. With regard to LUTS, patients undergoing ureteral rest were found to have reduced urinary frequency (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.001), straining (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.03), and urgency (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.0002). With regard to HRQOL, patients undergoing ureteral rest were found to have improved sleep disturbance (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.04). There was no difference in UTI rates before and after ureteral rest (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.48).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Patients undergoing ureteral rest prior to ureteral reconstruction may experience improvements in LUTS without compromising HRQOL outcomes or increasing the risk of UTIs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17562872261436896","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T16:22:48Z","timestamp":1774974168000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of lower urinary tract symptoms and health-related quality of life in patients undergoing ureteral rest prior to ureteral reconstruction"],"prefix":"10.1177","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3947-6343","authenticated-orcid":false,"given":"Jonathan","family":"Rosenfeld","sequence":"first","affiliation":[{"name":"Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurash","family":"Naser-Tavakolian","sequence":"additional","affiliation":[{"name":"Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devin","family":"Boehm","sequence":"additional","affiliation":[{"name":"Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Arteaga","sequence":"additional","affiliation":[{"name":"Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aidan","family":"Raikar","sequence":"additional","affiliation":[{"name":"Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaewoo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziho","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Urology, Feinberg School of Medicine, Northwestern University, 676 N. St Clair St., Suite 2300, Chicago, IL 60611, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,3,31]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/iju.15211"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2017.11.110"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2011.01.042"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000003482"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2021.05.032"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2021.01.058"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12894-019-0510-4"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)66434-8"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1159\/000052529"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)36966-5"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-018-1842-3"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4614-6937-7_10"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000048980.33855.90"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12894-022-01004-9"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.2017.0444"},{"issue":"8","key":"e_1_3_4_17_2","first-page":"491","article-title":"Ureteral stents: morbidity and impact on quality of life","volume":"7","author":"Leibovici D","year":"2005","unstructured":"Leibovici D, Cooper A, Lindner A, et al. Ureteral stents: morbidity and impact on quality of life. Isr Med Assoc J 2005; 7(8): 491\u2013494.","journal-title":"Isr Med Assoc J"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2024.05.042"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)36976-8"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000003200"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1089\/end.2004.18.891"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofx163.840"},{"key":"e_1_3_4_23_2","first-page":"104474","article-title":"Comparison complications rate between double-J ureteral stent and percutaneous nephrostomy in obstructive uropathy due to stone disease: a randomized controlled trial","volume":"81","author":"Al-Hajjaj M","year":"2022","unstructured":"Al-Hajjaj M, Sabbagh AJ, Al-Hadid I, et al. Comparison complications rate between double-J ureteral stent and percutaneous nephrostomy in obstructive uropathy due to stone disease: a randomized controlled trial. 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