{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T02:27:53Z","timestamp":1789784873132,"version":"4.0.1"},"reference-count":20,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ther Adv Med Oncol"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Bacterial peritonitis (BP) in patients with gastrointestinal (GI) cancer has been poorly described, and its prevalence is unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>This study aimed to evaluate in patients with both GI cancer and ascites the prevalence of BP, associated features, mechanisms, prognosis, and the diagnostic performance of neutrophil count in ascites.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>A retrospective, multicenter, observational study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>All patients with GI cancer and ascites who underwent at least one paracentesis sample analyzed for bacteriology over a 1-year period were included. BP was defined by a positive ascites culture combined with clinical and\/or biological signs compatible with infection. Secondary BP was defined as BP related to a direct intra-abdominal infectious source.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Five hundred fifty-seven ascites from 208 patients included were analyzed. Twenty-eight patients had at least one episode of BP and the annual prevalence rate of BP was 14%. Among the 28 patients with BP, 19 (65%) patients had proven secondary BP and 17 (59%) patients had multi-microbial BP, mainly due to Enterobacterales. A neutrophil count greater than 110\/mm\n                      <jats:sup>3<\/jats:sup>\n                      in ascites had negative and positive predictive values of 96% and 39%, respectively, for the diagnosis of BP. The median survival of patients with BP was 10\u2009days (interquartile range 6\u201340) after the diagnosis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>BP is not rare in patients with GI cancer and is associated with a poor short-term prognosis. When a patient with GI cancer is diagnosed with BP, a secondary cause should be sought. Further studies are needed to better define the best management of these patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17588359241258440","type":"journal-article","created":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T01:59:20Z","timestamp":1717639160000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Diagnosis and treatment of bacterial peritonitis in patients with gastrointestinal cancer: an observational multicenter study"],"prefix":"10.1177","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7489-9931","authenticated-orcid":false,"given":"Alix","family":"Riescher-Tuczkiewicz","sequence":"first","affiliation":[{"name":"Pancreatology and Digestive Oncology Department, Beaujon Hospital, AP-HP, Paris-Cit\u00e9 University, 100 Boulevard du G\u00e9n\u00e9ral Leclerc, Clichy 92110, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jules","family":"Gr\u00e9gory","sequence":"additional","affiliation":[{"name":"Inserm, INRAE, Center for Research in Epidemiology and Statistics, France and Radiology Department, H\u00f4pital Beaujon, AP-HP"},{"name":"Nord, Universit\u00e9 Paris Cit\u00e9 and Universit\u00e9 Sorbonne Paris Nord, FHU MOSAIC, Clichy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic","family":"Bert","sequence":"additional","affiliation":[{"name":"Bacteriology Department, Beaujon Hospital, AP-HP, Paris-Cit\u00e9 University, Clichy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magaly","family":"Zappa","sequence":"additional","affiliation":[{"name":"Service d\u2019Imagerie M\u00e9dicale, Centre Hospitalier de Cayenne, Cayenne, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Pellat","sequence":"additional","affiliation":[{"name":"Oncology Department, Saint Antoine Hospital, AP-HP, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie","family":"Lalande","sequence":"additional","affiliation":[{"name":"Bacteriology Department, Saint Antoine Hospital, AP-HP, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Gallois","sequence":"additional","affiliation":[{"name":"Digestive Oncology Department, Europ\u00e9en Georges Pompidou Hospital, AP-HP, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Luc","family":"Mainardi","sequence":"additional","affiliation":[{"name":"Bacteriology Department, Europ\u00e9en Georges Pompidou Hospital, AP-HP, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Baptiste","family":"Bachet","sequence":"additional","affiliation":[{"name":"Hepato-Gastroenterology Department, Piti\u00e9 Salp\u00eatri\u00e8re Hospital, AP-HP, Paris, 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