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All patients received IC with either the GP or NAB-TP regimen followed by concurrent chemoradiotherapy (CCRT). Propensity score matching (PSM) was used to balance baseline characteristics between the GP and NAB-TP groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      In total, 908 patients with LA-NPC (197 in the NAB-TP group) were enrolled. Before PSM, no statistically significant differences were observed between the NAB-TP and GP group in 5-year overall survival (OS; 98.67% vs 91.67%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.647), 5-year progression-free survival (PFS; 84.18% vs 66.22%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.587), 5-year locoregional relapse-free survival (LRFS; 88.13% vs 81.44%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.106), or 5-year distant metastasis-free survival (DMFS; 98.05% vs 89.88%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.106). After PSM, no differences were found in 5-year OS (98.60% vs 86.26%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.536), PFS (84.18% vs 66.22%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.587), LRFS (88.82% vs 76.14%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.757), or DMFS (97.95% vs 91.74%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.105). In the matched cohort, the NAB-TP group showed significantly lower incidences of anemia and thrombocytopenia than the GP group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>IC with the NAB-TP combined with CCRT showed comparable survival efficacy for LA-NPC patients compared with the GP, with reduced acute toxicity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/17588359251400977","type":"journal-article","created":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T12:25:04Z","timestamp":1764851104000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["NAB-paclitaxel and cisplatin versus gemcitabine and cisplatin as induction chemotherapy in locoregionally advanced nasopharyngeal carcinoma: a retrospective, propensity score-matched analysis"],"prefix":"10.1177","volume":"17","author":[{"given":"Qin","family":"Wang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China"},{"name":"Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zimeng","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China"},{"name":"Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, 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