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Although most observational studies indicate a significant linear relationship between maternal 25-hydroxyvitamin D and the above outcomes, some randomized controlled trials to date are inconclusive, mostly due to differences in study design and supplementation regimen. The currently available results indicate that vitamin D supplementation during pregnancy reduces the risk of preterm birth, low birth weight, dental caries of infancy, and neonatal infectious diseases such as respiratory infections and sepsis. This narrative review aims to summarize available trial results regarding the effect of low maternal vitamin D levels during pregnancy, in conjunction with neonatal outcomes on the field, with a discourse on the appropriate clinical approach of this important issue.<\/jats:p>","DOI":"10.1177\/1759720x16656810","type":"journal-article","created":{"date-parts":[[2016,7,13]],"date-time":"2016-07-13T10:27:42Z","timestamp":1468405662000},"page":"124-135","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":74,"title":["Maternal vitamin D levels during pregnancy and neonatal health: evidence to date and clinical implications"],"prefix":"10.1177","volume":"8","author":[{"given":"Spyridon N.","family":"Karras","sequence":"first","affiliation":[{"name":"First Department of Internal Medicine, Division of Endocrinology and Metabolism, AHEPA Hospital, Venizelou 34b, Pilea, PO Box 55535, Thessaloniki, 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