{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T21:34:48Z","timestamp":1778276088873,"version":"3.51.4"},"reference-count":191,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Musculoskeletal"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>Primary Sj\u00f6gren\u2019s syndrome (pSS) is a heterogeneous disease characterised by a wide spectrum of manifestations that vary according to the different stages of the disease and among different subsets of patients. The aim of this qualitative literature review is to summarise the recent advances that have been reported in pSS, ranging from the early phases to the established disease and its complications. We analysed the diagnostic, prognostic, and management aspects of pSS, with a look into future clinical and research developments. The early phases of pSS, usually antedating diagnosis, allow us to investigate the pathophysiology and risk factors of the overt disease, thus allowing better and timely patient stratification. Salivary gland ultrasound (SGUS) is emerging as a valid complementary, or even alternative, tool for histopathology in the diagnosis of pSS, due to a standardised scoring system with good agreement and performance. Other promising innovations include the application of artificial intelligence to SGUS, ultrasound-guided core needle biopsy, and a wide array of novel diagnostic and prognostic biomarkers. Stratifying pSS patients through the integration of clinical, laboratory, imaging, and histopathological data; differentiating between activity-related and damage-related manifestations; and identifying patients at higher risk of lymphoma development are essential steps for an optimal management and individualised treatment approach. As new treatment options are emerging for both glandular and systemic manifestations, there is a need for a more reliable treatment response evaluation. pSS is a complex and heterogeneous disease, and many distinct aspects should be considered in the different stages of the disease and subsets of patients. In recent years, efforts have been made to improve our understanding of the disease, and certainly in the coming years, some of these novelties will become part of our routine clinical practice, thus improving the management of pSS patients.<\/jats:p>","DOI":"10.1177\/1759720x221100295","type":"journal-article","created":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T06:48:58Z","timestamp":1653288538000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":21,"title":["Sj\u00f6gren syndrome: looking forward to the future"],"prefix":"10.1177","volume":"14","author":[{"given":"Sara","family":"Zandonella Callegher","sequence":"first","affiliation":[{"name":"Department of Rheumatology, Hospital of Bruneck, Bruneck, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1110-2518","authenticated-orcid":false,"given":"Ivan","family":"Giovannini","sequence":"additional","affiliation":[{"name":"Rheumatology Clinic, Department of Medicine, University of Udine, c\/o Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine","family":"Zenz","sequence":"additional","affiliation":[{"name":"Division of Rheumatology and Immunology, Medical University Graz, Graz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Manfr\u00e8","sequence":"additional","affiliation":[{"name":"Rheumatology Clinic, Department of Medicine, University of Udine, c\/o Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7884-6626","authenticated-orcid":false,"given":"Martin H.","family":"Stradner","sequence":"additional","affiliation":[{"name":"Division of Rheumatology and Immunology, Medical University Graz, Graz, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alojzija","family":"Hocevar","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marwin","family":"Gutierrez","sequence":"additional","affiliation":[{"name":"Division of Musculoskeletal and Rheumatic Diseases, Instituto Nacional de Rehabilitacion, Mexico City, Mexico"},{"name":"Rheumatology Center of Excellence, Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Quartuccio","sequence":"additional","affiliation":[{"name":"Rheumatology Clinic, Department of Medicine, University of Udine, c\/o Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"De Vita","sequence":"additional","affiliation":[{"name":"Rheumatology Clinic, Department of Medicine, University of Udine, c\/o Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0573-464X","authenticated-orcid":false,"given":"Alen","family":"Zabotti","sequence":"additional","affiliation":[{"name":"Rheumatology Clinic, Department of Medicine, University of Udine, c\/o Azienda Sanitaria Universitaria Friuli Centrale, Piazzale Santa Maria della Misericordia 15, 33100 Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,5,23]]},"reference":[{"key":"bibr1-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1007\/s12026-016-8844-4"},{"key":"bibr2-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200111)44:11<2633::AID-ART443>3.0.CO;2-9"},{"key":"bibr3-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-201381"},{"key":"bibr4-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/art.10445"},{"key":"bibr5-1759720X221100295","first-page":"315","volume":"38","author":"Fasano S","year":"2020","journal-title":"Clin Exp Rheumatol"},{"key":"bibr6-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2018.05.005"},{"key":"bibr7-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2016.217"},{"key":"bibr8-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/art.21062"},{"key":"bibr9-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2020-217646"},{"key":"bibr10-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.594096"},{"key":"bibr11-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2013.10.002"},{"key":"bibr12-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdsr.2019.09.006"},{"key":"bibr13-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.20.2337"},{"key":"bibr14-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kez052"},{"key":"bibr15-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.pathol.2019.08.012"},{"key":"bibr16-1759720X221100295","first-page":"351","volume":"10","author":"De Vita S","year":"1992","journal-title":"Clin Exp Rheumatol"},{"key":"bibr17-1759720X221100295","first-page":"1777","volume":"15","author":"de Clerck LS","year":"1988","journal-title":"J Rheumatol"},{"key":"bibr18-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9082492"},{"key":"bibr19-1759720X221100295","first-page":"146","volume":"37","author":"Zabotti A","year":"2019","journal-title":"Clin Exp Rheumatol"},{"key":"bibr20-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2020.602354"},{"key":"bibr21-1759720X221100295","author":"Devauchelle-Pensec V","year":"2019","journal-title":"Rheumatology (Oxford)"},{"key":"bibr22-1759720X221100295","first-page":"215","volume":"36","author":"Baldini C","year":"2018","journal-title":"Clin Exp Rheumatol"},{"key":"bibr23-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24017"},{"key":"bibr24-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kev385"},{"key":"bibr25-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12349"},{"key":"bibr26-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-017-1475-x"},{"key":"bibr27-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1111\/joim.12992"},{"key":"bibr28-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0195113"},{"key":"bibr29-1759720X221100295","doi-asserted-by":"crossref","first-page":"322","DOI":"10.55563\/clinexprheumatol\/13u0rt","volume":"38","author":"Geng Y","year":"2020","journal-title":"Clin Exp Rheumatol"},{"key":"bibr30-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24203"},{"key":"bibr31-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keaa441"},{"key":"bibr32-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10061171"},{"key":"bibr33-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780360309"},{"key":"bibr34-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-210571"},{"key":"bibr35-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2010.06.011"},{"key":"bibr36-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2009.10.004"},{"key":"bibr37-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1586\/1744666X.2014.884461"},{"key":"bibr38-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/243723"},{"key":"bibr39-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keaa105"},{"key":"bibr40-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201948129"},{"key":"bibr41-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2016.01.024"},{"key":"bibr42-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kez335"},{"key":"bibr43-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1038\/gene.2009.20"},{"key":"bibr44-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2019-216588"},{"key":"bibr45-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-23472-7"},{"key":"bibr46-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.594658"},{"key":"bibr47-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-020-00499-2"},{"key":"bibr48-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-019-0150-2"},{"key":"bibr49-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.a.23053"},{"key":"bibr50-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.03.055"},{"key":"bibr51-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1093\/chromsci\/bmw167"},{"key":"bibr52-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2020-218213."},{"key":"bibr53-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/art.37698"},{"key":"bibr54-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2017.04.005"},{"key":"bibr55-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16154-0"},{"key":"bibr56-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.278448"},{"key":"bibr57-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/art.39214"},{"key":"bibr58-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/art.39127"},{"key":"bibr59-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.088054"},{"key":"bibr60-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2018.10.005"},{"key":"bibr61-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/ard.61.6.554"},{"key":"bibr62-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1111\/ors.12405"},{"key":"bibr63-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-210448"},{"key":"bibr64-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2012.08.001"},{"key":"bibr65-1759720X221100295","first-page":"222","volume":"36","author":"Kroese FGM","year":"2018","journal-title":"Clin Exp Rheumatol"},{"key":"bibr66-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2018.04.011"},{"key":"bibr67-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2020.104154"},{"key":"bibr68-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2016.03.007"},{"key":"bibr69-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.coms.2013.09.005"},{"key":"bibr70-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kel266"},{"key":"bibr71-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/art.24903"},{"key":"bibr72-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-208304"},{"key":"bibr73-1759720X221100295","unstructured":"Cafaro G, Croia C, Argyropoulou OD, et al. One year in review 2019: Sj\u00f6gren\u2019s syndrome. Clin Exp Rheumatol 2019; 37: 3\u201315, https:\/\/www.clinexprheumatol.org\/abstract.asp?a=14480 (accessed 20 July 2021)."},{"key":"bibr74-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.2217\/bmm-2017-0297"},{"key":"bibr75-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keaa854"},{"key":"bibr76-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2018.08.007"},{"key":"bibr77-1759720X221100295","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1093\/rheumatology\/kew291","volume":"55","author":"Singh AG","year":"2016","journal-title":"Rheumatology (Oxford)"},{"key":"bibr78-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ket427"},{"key":"bibr79-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e318181e6af"},{"key":"bibr80-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2014-206418"},{"key":"bibr81-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-203305"},{"key":"bibr82-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2009.110619"},{"key":"bibr83-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20173"},{"key":"bibr84-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204615"},{"key":"bibr85-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2014-206008"},{"key":"bibr86-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-208504"},{"key":"bibr87-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2010.143743"},{"key":"bibr88-1759720X221100295","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1136\/ard.2010.143743","volume":"70","author":"Seror R","year":"2011","journal-title":"Ann Rheum Dis"},{"key":"bibr89-1759720X221100295","first-page":"29","volume":"36","author":"Moutsopoulos HM","year":"2018","journal-title":"Clin Exp Rheumatol"},{"key":"bibr90-1759720X221100295","first-page":"150","volume":"36","author":"De Vita S","year":"2018","journal-title":"Clin Exp Rheumatol"},{"key":"bibr91-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/S2665-9913(21)00122-3"},{"key":"bibr92-1759720X221100295","first-page":"198","volume":"36","author":"Brito-Zer\u00f3n P","year":"2018","journal-title":"Clin Exp Rheumatol"},{"key":"bibr93-1759720X221100295","unstructured":"HarmonicSS \u2013 Harmonization and integrative analysis of regional, national and international Cohorts on primary Sj\u00f6gren\u2019s Syndrome (pSS) towards improved stratification, treatment and health policy making, https:\/\/www.harmonicss.eu\/"},{"key":"bibr94-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kez578"},{"key":"bibr95-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9082620"},{"key":"bibr96-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/key392"},{"key":"bibr97-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2021.105132"},{"key":"bibr98-1759720X221100295","first-page":"89","volume":"61","author":"Manoussakis MN","year":"1986","journal-title":"Scand J Rheumatol Suppl"},{"key":"bibr99-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2015.07.002"},{"key":"bibr100-1759720X221100295","first-page":"53","volume":"38","author":"Cafaro G","year":"2020","journal-title":"Clin Exp Rheumatol"},{"key":"bibr101-1759720X221100295","first-page":"85","volume":"38","author":"Acar-Denizli N","year":"2020","journal-title":"Clin Exp Rheumatol"},{"key":"bibr102-1759720X221100295","first-page":"272","volume":"31","author":"Baldini C","year":"2013","journal-title":"Clin Exp Rheumatol"},{"key":"bibr103-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22859"},{"key":"bibr104-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/S2665-9913(19)30042-6"},{"key":"bibr105-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1177\/0961203314554251"},{"key":"bibr106-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.23629"},{"key":"bibr107-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keh714"},{"key":"bibr108-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0226498"},{"key":"bibr109-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/art.22658"},{"key":"bibr110-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ken164"},{"key":"bibr111-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2012.09.008"},{"key":"bibr112-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.reuma.2019.05.004"},{"key":"bibr113-1759720X221100295","first-page":"673","volume":"34","author":"Vreju FA","year":"2016","journal-title":"Clin Exp Rheumatol"},{"key":"bibr114-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.13811"},{"key":"bibr115-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-015-0657-7"},{"key":"bibr116-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24029"},{"key":"bibr117-1759720X221100295","first-page":"2198","volume":"54","author":"Luciano N","year":"2015","journal-title":"Rheumatology (Oxford)"},{"key":"bibr118-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-015-0751-x"},{"key":"bibr119-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12387"},{"key":"bibr120-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2020.101592"},{"key":"bibr121-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2017-211250"},{"key":"bibr122-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2019-215024"},{"key":"bibr123-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2020.581248"},{"key":"bibr124-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22264"},{"key":"bibr125-1759720X221100295","first-page":"140","volume":"37","author":"Inanc N","year":"2019","journal-title":"Clin Exp Rheumatol"},{"key":"bibr126-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2019-216122"},{"key":"bibr127-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0182287"},{"key":"bibr128-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.190849"},{"key":"bibr129-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2017-212268"},{"key":"bibr130-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0162787"},{"key":"bibr131-1759720X221100295","first-page":"228","volume":"38","author":"Diekhoff T","year":"2020","journal-title":"Clin Exp Rheumatol"},{"key":"bibr132-1759720X221100295","first-page":"470","volume":"71","author":"Hocevar A","year":"2019","journal-title":"Arthritis Rheumatol"},{"key":"bibr133-1759720X221100295","volume":"1","author":"Hoc\u02c7evar A","year":"2021","journal-title":"Rheumatology"},{"key":"bibr134-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keh187"},{"key":"bibr135-1759720X221100295","first-page":"1229","volume":"27","author":"Salaffi F","year":"2000","journal-title":"J Rheumatol"},{"key":"bibr136-1759720X221100295","first-page":"210","volume":"38","author":"Ferro F","year":"2020","journal-title":"Clin Exp Rheumatol"},{"key":"bibr137-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.676885"},{"key":"bibr138-1759720X221100295","first-page":"175","volume":"37","author":"Goules AV","year":"2019","journal-title":"Clin Exp Rheumatol"},{"key":"bibr139-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1177\/1120672118791936"},{"key":"bibr140-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/7627329"},{"key":"bibr141-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1080\/09273948.2019.1587470"},{"key":"bibr142-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.18-23984"},{"key":"bibr143-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.3109\/02713683.2011.631721"},{"key":"bibr144-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000001621"},{"key":"bibr145-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.14-15764"},{"key":"bibr146-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2019.08.007"},{"key":"bibr147-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1186\/s40780-018-0099-x"},{"key":"bibr148-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.4103\/jispcd.JISPCD_389_18"},{"key":"bibr149-1759720X221100295","first-page":"e552","volume":"23","author":"Wolff A","year":"2018","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"bibr150-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2017-212672"},{"key":"bibr151-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1111\/coa.12911"},{"key":"bibr152-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/lary.29233"},{"key":"bibr153-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1080\/14728214.2019.1634052"},{"key":"bibr154-1759720X221100295","first-page":"2249","volume":"54","author":"De Vita S","year":"2015","journal-title":"Rheumatology (Oxford)"},{"key":"bibr155-1759720X221100295","first-page":"199","volume":"37","author":"Gandolfo S","year":"2019","journal-title":"Clin Exp Rheumatol"},{"key":"bibr156-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2018-214720"},{"key":"bibr157-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-203991"},{"key":"bibr158-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.174.2.817"},{"key":"bibr159-1759720X221100295","first-page":"490","volume":"32","author":"De Vita S","year":"2014","journal-title":"Clin Exp Rheumatol"},{"key":"bibr160-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2021-eular.2170"},{"key":"bibr161-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/S2665-9913(19)30135-3"},{"key":"bibr162-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/art.41489"},{"key":"bibr163-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2020.102549"},{"key":"bibr164-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2020.09.006"},{"key":"bibr165-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.01699"},{"key":"bibr166-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/4896727"},{"key":"bibr167-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.3390\/biom11020251"},{"key":"bibr168-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kez142"},{"key":"bibr169-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.3390\/genes12060903"},{"key":"bibr170-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.5808\/GI.2018.16.4.e19"},{"key":"bibr171-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/S2665-9913(20)30057-6"},{"key":"bibr172-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1177\/0961203319857132"},{"key":"bibr173-1759720X221100295","first-page":"121","volume":"36","author":"Flores-Ch\u00e1vez A","year":"2018","journal-title":"Clin Exp Rheumatol"},{"key":"bibr174-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1186\/s13293-017-0146-6"},{"key":"bibr175-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2015.03.004"},{"key":"bibr176-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2018.00102"},{"key":"bibr177-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ker407"},{"key":"bibr178-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2019.1649596"},{"key":"bibr179-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.23736\/S0031-0808.20.04079-3"},{"key":"bibr180-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2019.102316"},{"key":"bibr181-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0211142"},{"key":"bibr182-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204634"},{"key":"bibr183-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2021.102648"},{"key":"bibr184-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10040644"},{"key":"bibr185-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.200482"},{"key":"bibr186-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.55563\/clinexprheumatol\/4c36nr"},{"key":"bibr187-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.187.2.8475299"},{"key":"bibr188-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24339"},{"key":"bibr189-1759720X221100295","first-page":"10","volume":"38","author":"Manfr\u00e8 V","year":"2020","journal-title":"Clin Exp Rheumatol"},{"key":"bibr190-1759720X221100295","unstructured":"Assessing the vascularization of salivary glands in patients with Sj\u00f6gren\u2019s syndrome \u2013 an OMERACT Ultrasound group reliability exercise. ACR Meeting Abstracts, https:\/\/acrabstracts.org\/abstract\/assessing-the-vascularization-of-salivary-glands-in-patients-with-sjogrens-syndrome-an-omeract-ultrasound-group-reliability-exercise\/ (accessed 7 September 2021)."},{"key":"bibr191-1759720X221100295","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2018-000789"}],"container-title":["Therapeutic Advances in Musculoskeletal Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1759720X221100295","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1759720X221100295","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1759720X221100295","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:38:32Z","timestamp":1777588712000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1759720X221100295"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":191,"alternative-id":["10.1177\/1759720X221100295"],"URL":"https:\/\/doi.org\/10.1177\/1759720x221100295","relation":{},"ISSN":["1759-720X","1759-7218"],"issn-type":[{"value":"1759-720X","type":"print"},{"value":"1759-7218","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"article-number":"1759720X221100295"}}